In recent posts, I have been discussing some important points about the reasonable meaning of homologies and differences in the proteome in the course of natural history. For the following discussion, just to be clear, I will accept a scenario of Common Descent (as explained in many recent posts) in the context of an ID approach. I will also accept the very reasonable concept that neutral or quasi-neutral random variation happens in time, and that negative (purifying) selection is the main principle which limits random variation in functional sequences. My main points are the following: Given those premises, homologies through natural history are certainly an indicator of functional constraints, because they mean that some sequence cannot be significantly transformed by random variation. Another way … Continue reading Homologies, differences and information jumps