Fine tuning Genetics Intelligent Design

Study: Enzymes act very specifically to control double-strand breaks

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It’s “an array of tools, each one finely tuned”:

Our cells are constantly dividing, and as they do, the DNA molecule — our genetic code — sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous. This kind of double-strand break can lead to genome rearrangements that are hallmarks of cancer cells, said James Daley, PhD, of the Long School of Medicine at The University of Texas Health Science Center at San Antonio.

Dr. Daley is first author of research, published June 18 in the journal Nature Communications, that sheds light on a double-strand break repair process called homologous recombination. Joined by senior authors Patrick Sung, DPhil, and Sandeep Burma, PhD, and other collaborators, Dr. Daley found that among an array of mechanisms that initiate homologous recombination, each one is quite different. Homologous recombination is initiated by a process called DNA end resection where one of the two strands of DNA at a break is chewed back by resection enzymes.

“What’s exciting about this work is that it answers a long-held mystery among scientists,” Dr. Daley said. “For a decade we have known that resection enzymes are at the forefront of homologous recombination. What we didn’t know is why so many of these enzymes are involved, and why we need three or four different enzymes that seem to accomplish the same task in repairing double-strand breaks.” …

“It’s like an engine mechanic who has a set of tools at his disposal,” Dr. Sung said. “The tool he uses depends on the issue that needs to be repaired. In like fashion, each DNA repair tool in our cells is designed to repair a distinctive type of break in our DNA.”

University of Texas Health Science Center at San Antonio, “When it comes to DNA repair, it’s not one tool fits all” at ScienceDaily

Paper. (open access)

Isn’t it amazing how all this fine-tuning “just happened.” Clearly, there is an order behind nature that did not just happen. If mathematics governs the universe, we should be trying to find out what really happened. It should be possible to find out if these complex structural developments are based on laws, not randomness.

3 Replies to “Study: Enzymes act very specifically to control double-strand breaks

  1. 1
    jawa says:

    Another proof that evolution is magic and Auntie Nature is very smart.
    🙂
    Engineers must learn much from this: stop designing and let time and chance take care of your projects. 🙂

  2. 2
    es58 says:

    “It’s like an engine mechanic who has a set of tools at his disposal,” Dr. Sung said. “The tool he uses depends on the issue that needs to be repaired. In like fashion, each DNA repair tool in our cells is *designed* to repair a distinctive type of break in our DNA.”

    Oh what a give away!

    Someone might be in danger of being cancelled

  3. 3
    martin_r says:

    Let me repeat what this Darwinian clown said: “our genetic code — sometimes gets broken.”

    yeah…

    This claim is pretty misleading… Even if the DNA molecule sometimes gets broken (only sometimes), there are literally MILLIONS of other problems with DNA molecule integrity – EVERY DAY, IN EVERY CELL”

    from Wikipedia:

    “DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.[1] In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day”

    “resulting in as many as 1 million individual molecular lesions per cell per day””

    “resulting in as many as 1 million individual molecular lesions per cell per day””

    “resulting in as many as 1 million individual molecular lesions per cell per day””

    First of all, HOW AN ERROR CAN BE IDENTIFIED, WHEN THERE IS NO FORESIGHT ? COULD SOME DARWINIAN CLOWN EXPLAIN IT TO ME ?

    Anyway, the double-strand-break is only part of the problem …

    There are claims, that Intelligent Design Theory can’t make any prediction:

    DNA proofreading/repair = this is exactly what would a ID Theory predict.

    HOW A DARWINIAN UNGUIDED PROCESS WITH NO FORESIGHT COULD DEVELOP “a collection of processes by which a cell identifies and corrects damage to the DNA” ?????????????

    Darwinians should see a doctor. The sooner the better…

    Without various DNA proofreading/repair mechanisms, THERE WILL BE NO LIFE !!!!!

    Look at how many errors need to be fixed everyday, in every cell !!!!!!

    Human body has TRILLIONS of cells, and in every single cell there are MILLIONS of errors per day!!!
    DO THE MATH!!!!

    NO DNA REPAIR, NO LIFE… DNA PROOFREADING/REPAIR HAS TO BE IN PLACE FROM THE BEGINNING…

    THE EXISTENCE OF DNA PROOFREADING/REPAIR SYSTEM IS UNDENIABLE PROOF OF CREATED LIFE.

    DO YOU REALIZE THAT YOU DARWINIAN CLOWNS ?

    PS:
    some types of DNA repair are even backed up. When the first round of repair somehow fails, there is a second round of repair to make sure it really gets repaired…

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