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Natural selection

Open Mike: Cornell OBI Conference Chapter 13—“Selection Threshold Severely Constrains Capture of Beneficial Mutations”—Concluding Comments excerpt

Researchers: Our findings raise a very interesting theoretical problem — in a large genome, how do the millions of low-impact (yet functional) nucleotides arise? It is universally agreed that selection works very well for high-impact mutations. However, ... Read More ›

Open Mike: Cornell OBI Conference Chapter 13—“Selection Threshold Severely Constrains Capture of Beneficial Mutations”—Abstract

Researchers: In all experiments that employ biologically reasonable parameters, we observe high STb values and a general failure of selection to preferentially amplify the large majority of beneficial mutations. Read More ›

Open Mike: Cornell OBI Conference Chapter 12—“Can Purifying Natural Selection Preserve Biological Information?”—Excerpt

Authors: The primary findings of this study are that the selection threshold problem is real and that it is more serious than generally recognized. These findings are very robust. Read More ›

Open Mike: Cornell OBI Conference Chapter 12—“Can Purifying Natural Selection Preserve Biological Information?”—Abstract

Authors: Indeed, we find that under most realistic circumstances, the large majority of harmful mutations are essentially unaffected by natural selection and continue to accumulate unhindered. This finding has major theoretical implications ... Read More ›

“So what is bad for the next generation may be good for our species in general.”

http://www.bbc.co.uk/news/health-19336438 In the above story, the combination of an empirical investigation of the here-and-now – what creationists like myself like to call “operational science” – together with speculative Darwinian faith, leads to this final take-home quote:  “The high rate of mutations is dangerous for the next generation but is generating diversity from which nature can select and further refine this product we call man,” he said. “So what is bad for the next generation may be good for our species in general.” Got that? It’s similar to the way in which your team losing this week and then repeating the performance next week results in winning the league at the end of the season.