Epigenetics

For about a year now, from reading various news items on newly published science articles, I’ve begun to consider not DNA, but RNA, the real driver of life. I think that DNA’s essential role is that of information storage–a hard drive, while RNA is like the BIOS system–it tells the “system” what it should be doing. I’ve been waiting for the right article to come along to present this newer view of genomic life. Well, it appears that the ‘right article’ has come along. This is from Phys.Org and this is the pdf online version of the article. From the Press Release via Phys.Org: Cells contain machinery that duplicates DNA into a new set that goes into a newly formed Read More ›

The good news from this mouse study is that if epigenetic stress is recognized, it can be reversed. That means, presumably, that it won’t be passed on: In a study published March 15 in Nature Neuroscience, researchers found that early-life stress in mice induces epigenetic changes in a particular type of neuron, which in turn make the animals more prone to stress later in life. Using a drug that inhibits an enzyme that adds epigenetic marks to histones, they also show that the latent effects of early-life stress can be reversed. “It is a wonderful paper because it is really advancing our ability to understand how events that happen early in life leave enduring signatures in the brain so that Read More ›