So 2/3 of the time, we have “ de novo emergence from ancestral non-genic sequences, such that homologues genuinely do not exist?” Okay. Somebody better go put their arm around the Selfish Gene. It’s tough being the Last Darwinian. Gene, we did not do this to you. Francis Collins and Craig Venter did this to you. Honest.
Remember the Selfish Gene? Aw, he was just playin’ you guys. You didn’t fall for that, did you?
Researchers: Even between chimps and humans, whose genomes are 99 per cent identical, there are dozens of TFs which recognize diverse motifs between the two species in a way that would affect expression of hundreds of different genes.
Let’s read the Nature abstract: Nature (2019) Article | Published: 15 May 2019 Total synthesis of Escherichia coli with a recoded genome Julius Fredens, Kaihang Wang, Daniel de la Torre, Louise F. H. Funke, Wesley E. Robertson, Yonka Christova, Tiongsun Chia, Wolfgang H. Schmied, Daniel L. Dunkelmann, Václav Beránek, Chayasith Uttamapinant, Andres Gonzalez Llamazares, Thomas […]
Researchers studied the thale cress (an Arabadopsis relative) which can have either a single or a double genome. Genome doubling is not good news: “It’s almost always a bad thing to have too much DNA, but we think that sometimes it makes for a ‘hopeful monster’ that just might flourish.” They seem to have found […]
The genome isn’t what it used to be.
If so, it’s remarkable outcome for genome mapping: So it has been dawning on us is that there is no prior plan or blueprint for development: Instructions are created on the hoof, far more intelligently than is possible from dumb DNA. That is why today’s molecular biologists are reporting “cognitive resources” in cells; “bio-information intelligence”; “cell […]
From ScienceDaily: When a building is damaged, a general contractor often oversees various subcontractors — framers, electricians, plumbers and drywall hangers — to ensure repairs are done in the correct order and on time. Similarly, when DNA is damaged, a molecular general contractor oversees a network of genetic subcontractors to ensure that the diverse cellular […]
The find kind of disappointed researchers who really wanted to know how humans come to use language but it is interesting in itself.
He thinks the Central Dogma of mitochondrial DNA needs to be rethought.
From ScienceDaily: University of Otago researchers have discovered information about a gene that sets primates — great apes and humans — apart from other mammals, through the study of a rare developmental brain disorder. … Dr O’Neill and research collaborators from Max Planck Institute of Psychiatry, Germany, then set forth to test the point that […]
A computer programmer looks at DNA … and finds it to be “amazing” code. From 2006 through 2017, Dutch entrepreneur and software developer Bert Hubert contributed from time to time to a web page where he listed many of the ways the workings of DNA can be likened to coding decisions by programmers. Some of […]
From ScienceDaily: Many wild and cultivated plants arise through the combination of two different species. The genome of these so-called polyploid species often consists of a quadruple set of chromosomes — a double set for each parental species — and thus has about twice as many genes as the original species. About 50 years ago, […]
The world’s simplest animal is trichoplax adhaerens. It is so simple that researchers wisely decided to forego the venerable Biological Species Concept that depends on an animal’s form (tricoplax doesn’t have much of a form) and just use genetics. But when evolutionary biologist Michael Eitel sequenced the genomes of several thousand of them, he was […]
Earlier this month, 15 genomes were released. The Vertebrate Genomes Project aims to sequence every extant vertebrate species—there are about 66,000—and to make them of the highest possible value. … “What we thought was a ‘genome’ back [when G10K was launched] really wasn’t suitable for in-depth studies,” G10K cofounder David Haussler, a computational biologist at […]