Uncommon Descent Serving The Intelligent Design Community

Huge mystery: Why are embryos timed correctly?

Share
Facebook
Twitter
LinkedIn
Flipboard
Print
Email

If we are committed to the idea that there is no design in nature, there is no comprehensive answer to this question:

So what are the timers that keep things trucking along at the right rate for any given organism, ensuring that it grows to the proper size and with all its parts in place? It’s a question that James Briscoe, a developmental biologist at the Francis Crick Institute in London, would love to answer. Take one lone example among many: motor neurons, the nerves that make muscles contract. These develop from precursor cells over a few days in mice but a week or two in humans — and the same thing happens when the cells are grown in a dish. “We can look at this carefully and demonstrate it’s the same genetic process, the same gene activities, the same mechanisms involved, and it’s just running slower in humans than in mouse embryos,” Briscoe says. “We’re trying to tackle that problem.”

Eryn Brown “How does the embryo make all its parts at just the right moments?” at Knowable Magazine

The research group can iterate in the greatest detail all the examples of the perfect timing throughout nature, via exquisitely designed controls, but dogma requires them to insist that it is all just an accident. A question arises: Will that requirement become a conceptual handicap?

Comments
@16: Note that the first sentence in the abstract is quite intriguing:
The genome is packaged and organized nonrandomly within the 3D space of the nucleus to promote efficient gene expression and to faithfully maintain silencing of heterochromatin.
nonrandomly? directed, guided? to promote? purpose-driven? Full text PDF https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355253/pdf/nihms-1007511.pdfOLV
February 5, 2020
February
02
Feb
5
05
2020
07:11 AM
7
07
11
AM
PDT
Coaching from the sidelines: the nuclear periphery in genome regulation
The genome is packaged and organized nonrandomly within the 3D space of the nucleus to promote efficient gene expression and to faithfully maintain silencing of heterochromatin. The genome is enclosed within the nucleus by the nuclear envelope membrane, which contains a set of proteins that actively participate in chromatin organization and gene regulation. Technological advances are providing views of genome organization at unprecedented resolution and are beginning to reveal the ways that cells co-opt the structures of the nuclear periphery for nuclear organization and gene regulation. These genome regulatory roles of proteins of the nuclear periphery have important influences on development, disease and ageing.
The more we know, the more is there for us to learn. And as science dig deeper into the cell, with the help of more advanced technology, the big picture looks more designed than before. These are not encouraging news for the Darwinian folks.OLV
February 4, 2020
February
02
Feb
4
04
2020
03:32 PM
3
03
32
PM
PDT
Truthfreedom, there is nothing quite like seeing, in the original, statements, such as : 'Remember that science is where you can find the answer to all your questions,' to make you LOL. I just did, when I checked on PavelU's post #10, just above yours, after reading your quote, instead of before it, and it took me quite by surprise. A new 'law of increasing returns' or, maybe a mysterious form of 'anti-entropy'. It's true I do never tire of reading their more inane 'apercus'. It's a pleasure that never dims with time or familiarity.Axel
February 4, 2020
February
02
Feb
4
04
2020
09:11 AM
9
09
11
AM
PDT
What a pleasure to see this discussion. It is a reminder how much absolute free will we have been given. God never forces us to see or acknowledge anything. We always have the choice to believe or disbelieve anything as we want to. However, we do not have the choice to decide what the consequences of the actions that we take based on our beliefs will be. Reality rules in the end. Blaise Pascal put it this way. There is enough information that the seeker will find God, but not enough to force the non-seeker to find Him. All our scientific knowledge is ultimately evidence for God. The person who finds random chance in everything has the right to believe that. I personally find it more of a miracle for the remarkable things in nature to be from an unguided process rather than an intelligent designer. In a similar way I believe that a medieval “forger” making the Shroud of Turin (with all the intricate details) would be more of a miracle that Jesus resurrecting from the dead while wrapped in the cloth. I would end with one warning. Failure to accept reality has consequences – whether you are crossing the street or facing immanent death. God BlessGCS
February 4, 2020
February
02
Feb
4
04
2020
08:20 AM
8
08
20
AM
PDT
What a pleasure to see this discussion. It is a reminder how much absolute free will we have been given. God never forces us to see or acknowledge anything. We always have the choice to believe or disbelieve anything as we want to. However, we do not have the choice to decide what the consequences of the actions that we take based on our beliefs will be. Reality rules in the end. Blaise Pascal put it this way. There is enough information that the seeker will find God, but not enough to force the non-seeker to find Him. All our scientific knowledge is ultimately evidence for God. The person who finds random chance in everything has the right to believe that. I personally find it more of a miracle for the remarkable things in nature to be from an unguided process than from an intelligent designer. In a similar way I believe that a medieval "forger" making the Shroud of Turin (with all the intricate details) would be more of a miracle that Jesus resurrecting from the dead while wrapped in the cloth. I would end with one warning. Failure to accept reality has consequences - whether you are crossing the street or facing immanent death. God BlessGCS
February 4, 2020
February
02
Feb
4
04
2020
08:13 AM
8
08
13
AM
PDT
PavelU
It takes that long because that’s how it is. The scientists at CERN should know why.
Absolute non sequitur! Evolution theory is good for some laughs.Truthfreedom
February 4, 2020
February
02
Feb
4
04
2020
06:50 AM
6
06
50
AM
PDT
PavelU
Remember that science is where you can find the answer to all your questions.
Ummmm. Our questions regarding the OOL have not been answered. 150+ years of nothing. Zero. Zilch. Nada. Only speculations and non-sense. Fairy-tales and just-so stories. Your scientistmist gospel is false. Buh.Truthfreedom
February 4, 2020
February
02
Feb
4
04
2020
06:31 AM
6
06
31
AM
PDT
Eugene @9: It takes that long because that’s how it is. The scientists at CERN should know why. You may want to ask them. They will explain it to you. Remember that science is where you can find the answer to all your questions.PavelU
February 4, 2020
February
02
Feb
4
04
2020
06:11 AM
6
06
11
AM
PDT
Forget the neurons. We don't even know why a stand-alone neuTron takes ~15 minutes to decay. Why not just 1 minute and why not 50 hours? We have no idea.Eugene
February 3, 2020
February
02
Feb
3
03
2020
07:38 PM
7
07
38
PM
PDT
Thus we are stuck with the question of, ‘Since the ultimate and final biological form that any organism may take is not reducible to any of the material particulars of that organism, just how does an organism achieve its final shape during embryological development?” Fortunately, due to advances in science, specifically due to advances in quantum biology and in quantum information theory, we are not in the dark as to answering this question. We now know that an immense amount of ‘positional information’ and/or ‘quantum information’ is coming into the developing embryo ‘from the outside’ by some ‘non-material’ method. At about the 41:00 minute mark of the following video, Dr. Wells, using a branch of mathematics called category theory, demonstrates that, during embryological development, information must somehow be added to the developing embryo, ‘from the outside’, by some ‘non-material’ method.
Design Beyond DNA: A Conversation with Dr. Jonathan Wells – video (41:00 minute mark) – January 2017 https://youtu.be/ASAaANVBoiE?t=2484
Moreover, the amount of ‘positional information’ that is somehow coming into a developing embryo from the outside by some non-material method is immense. Vastly outstripping, by many orders of magnitude, the amount of sequential information that is contained within DNA itself. As Doug Axe states in the following video, “there are a quadrillion neural connections in the human brain, that’s vastly more neural connections in the human brain than there are bits (of information) in the human genome. So,,, there’s got to be something else going on that makes us what we are.”
“There is also a presumption, typically when we talk about our genome, (that the genome) is a blueprint for making us. And that is actually not a proven fact in biology. That is an assumption. And (one) that I question because I don’t think that 4 billion bases, which would be 8 billion bits of information, that you would actually have enough information to specify a human being. If you consider for example that there are a quadrillion neural connections in the human brain, that’s vastly more neural connections in the human brain than there are bits (of information) in the human genome. So,,, there’s got to be something else going on that makes us what we are.” Doug Axe – Intelligent Design 3.0 – Stephen C. Meyer – video (1 hour 16 minute mark) https://www.youtube.com/watch?v=dvwBaD8-00w&t=4575s
And as the following article states, the information to build a human infant, atom by atom, would take up the equivalent of enough thumb drives to fill the Titanic, multiplied by 2,000.
In a TED Talk, (the Question You May Not Ask,,, Where did the information come from?) – November 29, 2017 Excerpt: Sabatini is charming.,,, he deploys some memorable images. He points out that the information to build a human infant, atom by atom, would take up the equivalent of enough thumb drives to fill the Titanic, multiplied by 2,000. Later he wheels out the entire genome, in printed form, of a human being,,,,: [F]or the first time in history, this is the genome of a specific human, printed page-by-page, letter-by-letter: 262,000 pages of information, 450 kilograms.,,, https://evolutionnews.org/2017/11/in-a-ted-talk-heres-the-question-you-may-not-ask/
On top of all that, as far as quantum information theory itself is concerned, this immense amount of positional information that is somehow coming into the developing embryo from the outside, by some non-material method, in order to bring the developing embryo to be so far out of thermodynamic equilibrium, and in order to achieve its final ‘form’, is found to be quote-unquote, “a property of an observer who describes a system.”
The Quantum Thermodynamics Revolution – May 2017 Excerpt: “Now in (quantum) information theory, we wouldn’t say entropy is a property of a system, but a property of an observer who describes a system.”,,, https://www.quantamagazine.org/quantum-thermodynamics-revolution/
In other words, some ‘outside observer’ who, (due to the quantum non-locality of the quantum coherence and/or entanglement of biological molecules), must necessarily exist outside the space-time of the universe, is now required in order for us to give an adequate causal account so that we may coherently explain how it is even possible for this immense amount of positional information to somehow be coming into the developing embryo ‘from the outside’, by some ‘non-material’ method. As should be needless to say, Darwinian materialists have no clue who this ‘outside observer’, who must necessarily be outside space-time itself, could possible be. Whereas, on the other hand, Christians have predicted such a ‘beyond space and time’ observer to be intimately involved in embryological development for thousands of years,
Psalm 139: 13-16 For you created my inmost being; you knit me together in my mother’s womb. I praise you because I am fearfully and wonderfully made; your works are wonderful, I know that full well. My frame was not hidden from you when I was made in the secret place, when I was woven together in the depths of the earth. Your eyes saw my unformed body; all the days ordained for me were written in your book before one of them came to be.
Supplemental notes:
Darwinian Materialism vs. Quantum Biology – Part II – video https://www.youtube.com/watch?v=oSig2CsjKbg How Quantum Mechanics and Consciousness Correlate – video (how consciousness, quantum information theory, and molecular biology correlate – 27 minute mark) https://youtu.be/4f0hL3Nrdas?t=1634
bornagain77
February 3, 2020
February
02
Feb
3
03
2020
06:42 PM
6
06
42
PM
PDT
As to embryological development in particular. EricMH recently brought up the topic of "final causality" vs. "efficient causality"
QUANTUM MECHANICS SHOWS THAT OUR UNIVERSE HAS PURPOSE - ERIC HOLLOWAY - JANUARY 31, 2020 Not only can two physically separated particles influence each other, they can influence each other through time Excerpt: Every day, we say things like, “I drove to the store to get some milk” or “I put on my shoes to go for a walk.” In our world, everything happens for a reason, a human reason. This reason is the cause of the action. But, counterintuitively, it occurs after the action. We only get the milk after having driven to the store. We only go for a walk after putting on the shoes. In philosophy, this sequence is called “final causality.” The world of physics is quite different. There, nothing happens for a reason. Particles have no inclinations or goals. Particle A bumps into particle B because it was first bumped by particle C. All causes precede their effects. In philosophy, this sequence is called efficient causality.,,, Recent open-access research on quantum physics adds an interesting new wrinkle to this dilemma:,,, ,,, two particles that are chronologically separated can influence each other such that particle A cannot be strictly said to have acted before or after particle B. Scientists believe that this result can be extended to causal entanglement. That means particle A can cause an effect in particle B after the effect has already occurred. Mind boggling. This state of affairs looks very similar to the final causality we discussed above. If the finding holds up, the scientists will have demonstrated that the physical realm is not immune to final causality,,, And herein lies the rub. If human observers are necessary for physical final causality to occur, how do humans come to have the capability in the first place? This question points to a yet even higher source of final causality that extends beyond the human realm, and is responsible for the final causality that humans exhibit. https://mindmatters.ai/2020/01/quantum-mechanics-shows-that-our-universe-has-purpose/
Amazingly, "final causality" vs. "efficient causality" plays more or less directly into embryological development. The following article states that without final causality, efficient causality is "worse than helpless" in regards to explaining 'the whole'
Final Causation, var. Final Causality Excerpt: Efficient causation is that kind of causation whereby the parts compose the whole; final causation is that kind of causation whereby the whole calls out its parts. Final causation without efficient causation is helpless; mere calling for parts is what a Hotspur, or any man, may do; but they will not come without efficient causation. Efficient causation without final causation, however, is worse than helpless, by far; it is mere chaos; and chaos is not even so much as chaos, without final causation; it is blank nothing. http://www.commens.org/dictionary/term/final-causation
Along that same line of reasoning, here is an interesting comment from Pastor Joe Boot,
“If you have no God, then you have no design plan for the universe. You have no prexisting structure to the universe.,, As the ancient Greeks held, like Democritus and others, the universe is flux. It’s just matter in motion. Now on that basis all you are confronted with is innumerable brute facts that are unrelated pieces of data. They have no meaningful connection to each other because there is no overall structure. There’s no design plan. It’s like my kids do ‘join the dots’ puzzles. It’s just dots, but when you join the dots there is a structure, and a picture emerges. Well, the atheists is without that (final picture). There is no preestablished pattern (to connect the facts given atheism).” Pastor Joe Boot – quote taken from 13:20 minute mark of the following video: Defending the Christian Faith – Pastor Joe Boot – video https://youtu.be/wqE5_ZOAnKo?t=797
The fact that ‘the whole’ can never be reduced to ‘the parts’, as is assumed within the reductive materialism of Darwinian evolution, also plays out with Gödel’s incompleteness theorem as well it plays out with quantum mechanics: Gödel’s incompleteness theorem can be stated succinctly as such: “Anything you can draw a circle around cannot explain itself without referring to something outside the circle—something you have to assume but cannot prove.”
“Gödel’s incompleteness theorem (1931), proves that there are limits to what can be ascertained by mathematics. Kurt Gödel halted the achievement of a unifying all-encompassing theory of everything in his theorem that: “Anything you can draw a circle around cannot explain itself without referring to something outside the circle—something you have to assume but cannot prove.” – Stephen Hawking & Leonard Miodinow, The Grand Design (2010)
In fact Gödel stated, “For something to be a whole, it has to have an additional object, say, a soul or a mind.”
“In materialism all elements behave the same. It is mysterious to think of them as spread out and automatically united. For something to be a whole, it has to have an additional object, say, a soul or a mind.” – Kurt Gödel – Hao Wang’s supplemental biography of Gödel, A Logical Journey, MIT Press, 1996. [9.4.12]
Gödel’s incompleteness theorem is not just some abstract mathematical proof but has now been extended to quantum physics. In the following article entitled ‘Quantum physics problem proved unsolvable: Gödel and Turing enter quantum physics’, which studied the derivation of macroscopic properties from a complete microscopic description, the researchers remark that even a perfect and complete description of the microscopic properties of a material is not enough to predict its macroscopic behaviour.,,, The researchers further commented that their findings challenge the reductionists’ point of view, as the insurmountable difficulty lies precisely in the derivation of macroscopic properties from a microscopic description.”
Quantum physics problem proved unsolvable: Gödel and Turing enter quantum physics – December 9, 2015 Excerpt: A mathematical problem underlying fundamental questions in particle and quantum physics is provably unsolvable,,, It is the first major problem in physics for which such a fundamental limitation could be proven. The findings are important because they show that even a perfect and complete description of the microscopic properties of a material is not enough to predict its macroscopic behaviour.,,, “We knew about the possibility of problems that are undecidable in principle since the works of Turing and Gödel in the 1930s,” added Co-author Professor Michael Wolf from Technical University of Munich. “So far, however, this only concerned the very abstract corners of theoretical computer science and mathematical logic. No one had seriously contemplated this as a possibility right in the heart of theoretical physics before. But our results change this picture. From a more philosophical perspective, they also challenge the reductionists’ point of view, as the insurmountable difficulty lies precisely in the derivation of macroscopic properties from a microscopic description.” http://phys.org/news/2015-12-quantum-physics-problem-unsolvable-godel.html
And indeed this ‘insurmountable difficulty’ plays out in biology. We find that Darwinian mechanisms are simply at a complete loss to explain how the basic ‘form’ of any particular organism may take is achieved. For instance, contrary to what Darwinists presupposed, DNA is not a ‘blueprint’ for an organism,
DNA is life’s blueprint? No, there’s far more to it than that – 10 June 2015 https://www.newscientist.com/article/mg22630251-000-dna-is-lifes-blueprint-no-theres-far-more-to-it-than-that/
Indeed, DNA does not even control its own shape, much less does it control the final shape of a organism,
Tissue-specific spatial organization of genomes – June 21, 2004 Results ,,, Our results demonstrate that the spatial organization of genomes is tissue-specific and point to a role for tissue-specific spatial genome organization in the formation of recurrent chromosome arrangements among tissues. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC463291/
As Dr. Jonathan Wells states, “I now know as an embryologist,,,Tissues and cells, as they differentiate, modify their DNA to suit their needs. It’s the organism controlling the DNA, not the DNA controlling the organism.”
Ask an Embryologist: Genomic Mosaicism – Jonathan Wells – February 23, 2015 Excerpt: humans have a “few thousand” different cell types. Here is my simple question: Does the DNA sequence in one cell type differ from the sequence in another cell type in the same person?,,, The simple answer is: We now know that there is considerable variation in DNA sequences among tissues, and even among cells in the same tissue. It’s called genomic mosaicism. In the early days of developmental genetics, some people thought that parts of the embryo became different from each other because they acquired different pieces of the DNA from the fertilized egg. That theory was abandoned,,, ,,,(then) “genomic equivalence” — the idea that all the cells of an organism (with a few exceptions, such as cells of the immune system) contain the same DNA — became the accepted view. I taught genomic equivalence for many years. A few years ago, however, everything changed. With the development of more sophisticated techniques and the sampling of more tissues and cells, it became clear that genetic mosaicism is common. I now know as an embryologist,,,Tissues and cells, as they differentiate, modify their DNA to suit their needs. It’s the organism controlling the DNA, not the DNA controlling the organism. http://www.evolutionnews.org/2015/02/ask_an_embryolo093851.html
Nor is the basic form of any organism reducible to any of the other material particulars in biology that Darwinists may wish to invoke,
Darwinism (Materialism) vs Biological Form – video https://www.youtube.com/watch?v=JyNzNPgjM4w
bornagain77
February 3, 2020
February
02
Feb
3
03
2020
06:40 PM
6
06
40
PM
PDT
What does time mean in development?
Biology is dynamic. Timescales range from frenetic sub-second ion fluxes and enzymatic reactions to the glacial millions of years of evolutionary change. Falling somewhere in the middle of this range are the processes we usually study in development: cell division and differentiation, gene expression, cell-cell signalling, and morphogenesis. But what sets the tempo and manages the order of developmental events? Are the order and tempo different between species? How is the sequence of multiple events coordinated? Here, we discuss the importance of time for developing embryos, highlighting the necessity for global as well as cell-autonomous control. New reagents and tools in imaging and genomic engineering, combined with in vitro culture, are beginning to offer fresh perspectives and molecular insight into the origin and mechanisms of developmental time.
Taken together, studies from a range of systems are beginning to shed light on the molecular and genetic mechanisms that encode and interpret developmental time. Comparisons between species and results from different tissues are identifying the players and mechanisms that account for the order and tempo of developmental events. New reagents, particularly novel imaging reporters, and the development of new techniques, such as in vitro tissue culture methods, are offering a fresh perspective on this long-standing problem. This is sharpening the focus on the underlying principles and relevant questions, answers to which will provide insight into a fundamental aspect of embryo development.
OLV
February 3, 2020
February
02
Feb
3
03
2020
05:26 PM
5
05
26
PM
PDT
The more we know, more is there for us to learn: The Epitranscriptome
The regulation of the transcriptome is key to cellular processes that underpin cell biology, development and tissue function. All classes of cellular RNA are subject to post-transcriptional modification, be it by direct chemical modification, editing or non-templated nucleotide additions. It is now emerging that the modification status of the transcriptome is dynamic and responsive to environmental/developmental cues. Together, this has elicited the realisation of an ‘epitranscriptome’ where post-transcriptional RNA modification coupled with recruitment of effector RNA binding proteins dynamically regulates genomic output. Importantly, mutations in setting or reading RNA modifications are causative of many human diseases or congenital disorders. This meeting aims to explore all aspects of this emerging topic, from methods development to molecular mechanism. Most importantly, the meeting will place an emphasis on the contribution of RNA modification to mammalian development, tissue homeostasis and disease.
Session Topics RNA modification I (m6A) RNA modifications in stem cells and development RNA modification II (m5C, m1A, 3’ terminal additions, etc) RNA modification pathways in physiology and pathology Emerging concepts      OLV
February 3, 2020
February
02
Feb
3
03
2020
04:31 PM
4
04
31
PM
PDT
The most astonishing thing about neurons is that they are manufactured in one factory, then shipped to the correct destination via railroads that are built for the task. Each neuron is tagged (somehow) with its intended destination before the shipping. http://polistrasmill.blogspot.com/2018/06/axon-first.htmlpolistra
February 3, 2020
February
02
Feb
3
03
2020
04:17 PM
4
04
17
PM
PDT
Control Systems Engineers drool at the sight of so much wonder. Simply incredible.
I agree. The intricacy and delicacy of those mechanisms is mind-boggling. According to evolutionists: "nah, random trash".Truthfreedom
February 3, 2020
February
02
Feb
3
03
2020
03:55 PM
3
03
55
PM
PDT
Not only are "Embryos Timed Correctly" but they are also found to be "optimal." As the following recent 2019 article stated, “It’s now known that some form of positional information makes genes variously switch on and off throughout the embryo, giving cells distinct identities based on their location.,,, that cells extract as much useful information from their complex surroundings as is theoretically possible.,,, when researchers have been able to appropriately determine what cells are doing, many have been surprised to see clear indications of optimization.,,,”
The Math That Tells Cells What They Are - March 13, 2019 Excerpt: It’s now known that some form of positional information makes genes variously switch on and off throughout the embryo, giving cells distinct identities based on their location.,,, That mounting evidence is leading some biologists to a bold hypothesis: that where information is concerned, cells might often find solutions to life’s challenges that are not just good but optimal — that cells extract as much useful information from their complex surroundings as is theoretically possible.,,, when researchers have been able to appropriately determine what cells are doing, many have been surprised to see clear indications of optimization.,,, “I don’t think optimization is an aesthetic or philosophical idea. It’s a very concrete idea,” Bialek said.,,, https://www.quantamagazine.org/the-math-that-tells-cells-what-they-are-20190313/
"Optimal" is not just some word that they are carelessly tossing around. When they describe a biological system as being in a 'optimal' state, they mean exactly what they are saying. As the following article states, "In each instance, biophysicists have calculated, the system couldn’t get faster, more sensitive or more efficient without first relocating to an alternate universe with alternate physical constants."
William Bialek: More Perfect Than We Imagined - March 23, 2013 Excerpt: Scientists have identified and mathematically anatomized an array of cases where optimization has left its fastidious mark, among them the superb efficiency with which bacterial cells will close in on a food source; the precision response in a fruit fly embryo to contouring molecules that help distinguish tail from head; and the way a shark can find its prey by measuring micro-fluxes of electricity in the water a tremulous millionth of a volt strong — which, as Douglas Fields observed in Scientific American, is like detecting an electrical field generated by a standard AA battery “with one pole dipped in the Long Island Sound and the other pole in waters of Jacksonville, Fla.” In each instance, biophysicists have calculated, the system couldn’t get faster, more sensitive or more efficient without first relocating to an alternate universe with alternate physical constants. http://darwins-god.blogspot.com/2013/03/william-bialek-more-perfect-than-we.html
Moreover, as the following article states, “There are a surprisingly limited number of ways a network could be constructed to perform perfect adaptation.”,,, Moreover, the "amazing and surprising" outcome of the study is applicable to any living organism or biochemical network of any size.,,,”
Math sheds light on how living cells 'think' - May 2, 2018 Excerpt: "Proteins form unfathomably complex networks of chemical reactions that allow cells to communicate and to 'think' --,,, "We could never hope to measure the full complexity of cellular networks -- the networks are simply too large and interconnected and their component proteins are too variable. "But mathematics provides a tool that allows us to explore how these networks might be constructed in order to perform as they do.,,, Dr Araujo's work has focused on the widely observed function called perfect adaptation -- the ability of a network to reset itself after it has been exposed to a new stimulus. "An example of perfect adaptation is our sense of smell," she said. "When exposed to an odour we will smell it initially but after a while it seems to us that the odour has disappeared, even though the chemical, the stimulus, is still present. "Our sense of smell has exhibited perfect adaptation. This process allows it to remain sensitive to further changes in our environment so that we can detect both very faint and very strong odours. "This kind of adaptation is essentially what takes place inside living cells all the time. Cells are exposed to signals -- hormones, growth factors, and other chemicals -- and their proteins will tend to react and respond initially, but then settle down to pre-stimulus levels of activity even though the stimulus is still there. "I studied all the possible ways a network can be constructed and found that to be capable of this perfect adaptation in a robust way, a network has to satisfy an extremely rigid set of mathematical principles. There are a surprisingly limited number of ways a network could be constructed to perform perfect adaptation.,,, Professor Lance Liotta, said the "amazing and surprising" outcome of Dr Araujo's study is applicable to any living organism or biochemical network of any size.,,, https://www.sciencedaily.com/releases/2018/05/180502094636.htm
bornagain77
February 3, 2020
February
02
Feb
3
03
2020
03:53 PM
3
03
53
PM
PDT
This is an excellent topic. Very much ID on steroids. Here's a video of a recent presentation Dr James Briscoe gave in the US. Note at time 00:40 Dr Briscoe says: "as a developmental biologist what I'm interested in is understanding how tissues make the right cells in the right place at the right time and in the right numbers" Control Systems Engineers drool at the sight of so much wonder. Simply incredible.OLV
February 3, 2020
February
02
Feb
3
03
2020
03:15 PM
3
03
15
PM
PDT

Leave a Reply