Further to “Proteome ‘more complex than previously thought’”, from Science:
“The prevalent view was that information transfer was from genome to transcriptome to proteome. What these efforts show is that it’s a two-way road—proteomics can be used to annotate the genome. The importance is that, using these datasets, we can improve the annotation of the genome and the algorithms that predict transcription and translation,” said Steen. “The genomics field can now hugely benefit from proteomics data.”
Hey, aren’t these the cement shoes of the Central Dogma? Remember when One gene coded for one protein?
See also: Information killed the Central Dogma too
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