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Researchers: Genes can be suppressed by sound stimulation

“mechanosensitive” genes suppressed by audible sound/Kyoto University, Eiri Ono

From ScienceDaily:

In a new PLOS ONE study, scientists from Kyoto University’s Graduate School of Biostudies have shown that certain ‘mechanosensitive’ genes are suppressed when subjected to audible sound. Moreover, these effects vary depending on cell type, where some don’t show any sensitivity.

“One such gene we examined helps in bone formation, and is known to be upregulated with low-intensity ultrasound pulses,” continues Kumeta. “The other genes were associated with wound healing and the extracellular matrix.”

Series of cells were placed in an incubator outfitted with a full-range loudspeaker. After several hours of exposure to sounds with specific frequencies, expression levels of the target genes were analysed.

The team found that these mechanosensitive genes were suppressed by up to 40% with only one to two hours of exposure. Moreover, after the genes were suppressed, the effects remained for at least four hours.

The response was also dependent on waveforms and decibel levels. When exposing the cells to square or triangle waves, gene suppression was not as significant compared to sine waves on any tested frequency. Additionally, some genes did not show compounded suppression at higher decibels while others were reduced even further. Kumeta says this indicates that sound stimulation induces different responses in the cell.

The results also showed that such stimulations affect cells differently according to cell type. Cells that would eventually become bone or skeletal muscle showed the most suppression, while cells that had already differentiated had almost no response Paper. (public access) – Masahiro Kumeta, Daiji Takahashi, Kunio Takeyasu, Shige H. Yoshimura. Cell type-specific suppression of mechanosensitive genes by audible sound stimulation. PLOS ONE, 2018; 13 (1): e0188764 DOI: 10.1371/journal.pone.0188764 More.

If this gene alteration (“certain ‘mechanosensitive’ genes are suppressed”)is found in nature as well as lab-grown tissues, the next question would be, can it be inherited (epigenetics)? To what effect? If noise pollution is harmful to genes, it is more than a lifestyle choice.

See also: Epigenetics: How famine leaves its mark on genes


Epigenetic change: Lamarck, wake up, you’re wanted in the conference room!

“Astronomers now find they have painted themselves into a corner because they have proven, by their own methods, that the world began abruptly in an act of creation to which you can trace the seeds of every star, every planet, every living thing in this cosmos and on the earth. And they have found that all this happened as a product of forces they cannot hope to discover. That there are what I or anyone would call supernatural forces at work is now, I think, a scientifically proven fact.” ? Robert Jastrow Tom Robbins
AMEN - “At this moment it seems as though science will never be able to raise the curtain on the mystery of creation. For the scientist who has lived by his faith in the power of reason, the story ends like a bad dream. He has scaled the mountains of ignorance; he is about to conquer the highest peak; as he pulls himself over the final rock, he is greeted by a band of theologians who have been sitting there for centuries.” ? Robert Jastrow Tom Robbins
More sounds that produced an interesting effect: “Talitha cumi,” which means, “Little girl, I say to you, arise.” “Lazarus, come out.” “It is finished,” awstar
Now this is INTERESTING!!!!! The differential response to formants is a potentially world-changing finding. In the beginning was the Word, and the Word was with God, and the Word was God. Literally. And God said.... Literally. polistra

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