Transcription Factors Controlling Transcription Factors

'It's becoming extremely problematic to explain how the genome could arise and how these multiple levels of overlapping information could arise, since our best computer programmers can't even conceive of overlapping codes. The genome dwarfs all of the computer information technology that man has developed. So I think that it is very problematic to imagine how you can achieve that through random changes in a code.,,, More and more it looks like top down design and not just bottom up chance discovery of making complex systems.' - Dr. John Sanford http://www.youtube.com/watch?v=YemLbrCdM_s Poly-Functional Complexity equals Poly-Constrained Complexity https://docs.google.com/document/d/1xkW4C7uOE8s98tNx2mzMKmALeV8-348FZNnZmSWY5H8/edit bornagain77

Today's belief in ineluctable certainty is the true innovation-killer of our age. In this environment, the best an audacious manager can do is to develop small improvements to existing systems, climbing the hill, as it were, toward a local maximum, trimming fat, occasionally eking out the occasional tiny innovation - like city planners painting bicycle lanes on the streets as a gesture toward solving our energy problems. Any strategy that involves crossing a valley - accepting short-term losses to reach a higher hill in the distance - will soon be brought to a halt by the demands of a system that celebrates short-term gains, tolerates stagnation, but condemns anything else as failure. In short, a world where big stuff can never get done. - Neal Stephenson

Sound familiar? Mung