The Biological Frontier of Physics
Rob Phillips and Stephen R. Quake
May 2006, page 38
… The cell’s nanometer-scale machines are mostly protein molecules, although a few are made from RNA, and they are capable of surprisingly complex manipulations. They perform almost all the important active tasks in the cell: metabolism, reproduction, response to changes in the environment, and so forth. They are incredibly sophisticated, and they, not their manmade counterparts, represent the pinnacle of nanotechnology. Yet scientists have no general theory for their assembly or operation.
[AND YET …]
It is surely one of the triumphs of evolution that Nature discovered how to make highly accurate machines in such a noisy environment.