Stem-cell scientists redefine how blood is made, toppling conventional ‘textbook’ view
The findings, published online in the journal Science, prove “that the whole classic ‘textbook’ view we thought we knew doesn’t actually even exist,” says principal investigator John Dick, Senior Scientist at Princess Margaret Cancer Centre, University Health Network (UHN), and Professor in the Department of Molecular Genetics, University of Toronto.
“Instead, through a series of experiments we have been able to finally resolve how different kinds of blood cells form quickly from the stem cell — the most potent blood cell in the system — and not further downstream as has been traditionally thought,” says Dr. Dick, who holds a Canada Research Chair in Stem Cell Biology and is also Director of the Cancer Stem Cell Program at the Ontario Institute for Cancer Research. He talks about the research at www.youtu.be/D08FMKDppVQ .
The research also topples the textbook view that the blood development system is stable once formed. Not so, says Dr. Dick. “Our findings show that the blood system is two-tiered and changes between early human development and adulthood.”
In short, it is all more complex than thought. All just happened by accident, though, right?
Zachriel, Bimbette, from Airhead TV, is on Line 2, and well, she’s just really confused and wants to talk to you. Looking earnest and concerned about people who doubt Top Ideas isn’t working for her like it used to.
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