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Paper making the rounds: “Why Early Life Did Not Evolve Through Natural Selection”

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Liane Gabora, a computer science and psychology major, writes in Self-Other Organization: Why Early Life Did Not Evolve Through Natural Selection (published at Philpapers ):

Abstract: The improbability of a spontaneously generated self-assembling molecule has suggested that life began with a set of simpler, collectively replicating elements, such as an enclosed autocatalytic set of polymers (or autocell). Since replication occurs without a self-assembly code, acquired characteristics are inherited. Moreover, there is no strict distinction between alive and dead; one can only infer that an autocell was alive if it replicates. These features of early life render natural selection inapplicable to the description of its change-of-state because they defy its underlying assumptions. Moreover, natural selection describes only randomly generated novelty; it cannot describe the emergence of form at the interface between organism and environment.

Self-organization is also inadequate because it is restricted to interactions amongst parts; it too cannot account for context-driven change. A modified version of selection theory or self-organization would not work because the description of change-of-state through interaction with an incompletely specified context has a completely different mathematical structure, i.e. entails a non-Kolmogorovian probability model. It is proposed that the evolution of early life is appropriately described as lineage transformation through context-driven actualization of potential, with self-organized change-of-state being a special case of no contextual influence, and competitive exclusion of less fit individuals through a selection-like process possibly (but not necessarily) playing a secondary role. It is argued that natural selection played an important role in evolution only after genetically mediated replication was established.

Okay. One detail: We watched the demo. That’s some hat. But where’s the rabbit?  Thoughts?

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"??????" ????? ?????? ??? ????? ?"? ????? ???? ???? ?????? ?? ??????. ???? ?? ?????. Evolution Derives From Gravity The quantity of mass in the universe is constant since the universe started its last self-replication, since its last singularity, its last pre-big bang re-birth conception. All Science Disciplines derive from, start and end, evolve and survive in the direction and manner set by the framework of gravity, the monotheism of the universe. All things, everything in the universe, derive from the gravity of the universe. Every mass format exists, like the universe itself, in one of two states: in an inert state like the material (most probably the gravitons, the elementary particles of the universe) stored in black holes, and in an energetic state, in motion therefore capable of performing work. Due to this mass-energy dualism also the quantity of energy in the universe is constant. Since the last big-bang all mass formats undergo the same cyclic sequence like the universe itself i.e. birth – evolution – survival – replication. In order to survive and to repeat this sequence every mass format must remain in an energetic state. And since the universe mass/energy quantity is constant there is a melee for it by all mass formats, and the unlucky formats are swallowed and digested by the luckier mass formats. It’s indeed, in fact, an eat or be eaten universe… Dov Henis (comments from 22nd century) http://universe-life.com/ http://universe-life.com/2011/07/13/greed-cancer-cells-follow-laws-of-evolution/ ============================================================ THE GREAT science feat in 2013 ?? ???? ????? ????? The 2013 gravity comprehension/definition is the greatest science feat since the early 1920s. Learn what, scientifically, natural gravity is and what evolution is. Think of the consequences re classical science of this comprehension of gravity… ??? ???? ????? ?? ???? Origin And Nature of the Universe, the greatest science feat since the early 1920s. New Science 2013 versus classical science. Classical Science Is Anticipated/Replaced By The 2013 Gravity Comprehension !!! http://universe-life.com/2014/02/24/gravity/ Attn classical science hierarchy, including Darwin and Einstein… “I hope that now you understand what gravity is and why it is the monotheism of the universe…” DH ================================= Gravity is the natural selection of self-attraction by the elementary particles of an evolving system on their cyclical course towards the re- self-replication of the system. Period ( Gravitons are the elementary particles of the universe. RNA nucleotides genes and serotonin are the elementary particles of Earth life) ?? ?????? ?? ?????? ??? ?????? ?????? ???????? ????? ?? ?????? ????? ?? ????? ?????? ????? ???????? ???????? ???? ???????. ????? ( ????????? ??? ????? ????? ?? ?????. ?????, ???????????? ?? ????? ???????????, ??????????, ?? ???????? ???????? ?? ??? ???? ????) Dov Henis(comments from 22nd century) http://universe-life.com/2013/11/14/subverting-organized-religious-science/ http://universe-life.com/2013/09/03/the-shortest-grand-unified-theory/ http://universe-life.com/2013/09/30/science-adjust-vision-concepts-beyond-aaas-trade-union-religion/ PS: Note, again: - Classical Science Is Anticipated/Replaced By The 2013 Gravity Comprehension !!! - Think of the consequences re classical science of this comprehension of gravity… DH ?.?. ???? ???? ?? ?????? ????? ???? ?????? ????/????/???? ??? ????? ?????? ???? ?????. ?? ?? ??- ????? ?? ???????/?????? ?? ????? ????? ????????? ??????? ?? ???"? ?????? ????? ???????/?????? ?? ??? ?"??????/???" ??????? ?????? ??????? ???????? ???? ?? ?"??????", ?????? ?? ???? ??????/?????/????? ?? ???? 2013 ???? ???????, ?????? ?? ???? ???????? ?????? ?? ???? ???????. ??-????? ?? ??? ???? ???? ?????? ?????? /????/???? ?? ?????. ??(????? ????? ?-22) ============================================================================= What would the human world be without god, or without science (May 1/ 3 2014) Scientifically natural gravity is the monotheism of the universe. The reverence- to- god- tradition, religion of the present Western culture, was introduced by Abraham (2117-1942 BCE) from the Casdites-Babylonians, in whom it was evoked by the sight of the apparently "praying" palm trees, with their palm-like leaves, rewarded with "God's gift", in Persian "Bagdad" (bag=god, dad=dat hence date-fruit, data= given/gift. This reverence-culture/ tradition was re- adopted by the Jews exiled into Babylonia (586 BCE) , and later adopted also by the Persians who conquered the Babylonian empire, and later adopted also by Alexander , who conquered the Persian empire, and later adopted also by the Greeks and finally adopted from the Greeks also by the Romans and by their following Western world heritage… - What would a world without god look like? - What would a world without science look like? Science = knowledge about or study of the natural world based on facts learned through experiments and observation God = the perfect and all-powerful spirit or being that is worshipped especially by Christians, Jews, and Muslims as the one who created and rules the universe a spirit or being that has great power, strength, knowledge, etc., and that can affect nature and the lives of people. : one of various spirits or beings worshipped in some religions. Science and god are incompatible. Incompatible. The present world is a god-believer scienceless world, conducted by ruthlessly competing-for- energy interests , with consequent catastrophes to humanity... Dov Henis (comments from 22nd century) http://universe-life.com/ http://universe-life.com/2006/03/12/inception-and-prevalence-of-western-monotheism/ Dov Henis
On The Essence And Matrix Of The Universe-Life The following three sentences are the shortest data-based TOE…seriously. Natural Selection/ Self Replication/ Gravity - Self-replication is the ultimate mode of natural selection is the essence and drive and purpose of the universe. Period. - The pre-Big-Bang singularity is the ultimate self-replication of the cycling mass-energy universe. Period. - Earth’s RNA nucleotides life is just one of the myriad modes of self-replication. Dov Henis (comments from 22nd century) http://universe-life.com/ http://universe-life.com/2012/11/14/701/ -The 20yrs development, and comprehensive data-based scientism worldview, in a succinct format. -The Genome is a base organism evolved, and continuously modified, by the genes of its higher organism as their functional template. - Everything in the universe derives from mass-energy duality, from the universe cycle between the two poles all-mass-all energy. - The Origin Of Gravitons is the ONLY thing unknown-unexplained in the Scientism Universe. Dov Henis
Origin And Nature Of Earth Life, An Update… Liberate your mind from concepts dictated by religious trade-union AAAS. Life is just another mass format + re-comprehend natural selection + natural selection is ubiquitous, for all mass formats. Life Evolves by Naturally Selected Organic Matter I. Homegrown Organic Matter Found on Mars, But No Life http://news.sciencemag.org/sciencenow/2012/05/homegrown-organic-matter-found-o.html?ref=em II. EarthLife Genesis From Aromaticity/H-Bonding http://universe-life.com/2011/09/30/earthlife-genesis-from-aromaticityh-bonding/ September 30, 2011 A. Purines and pyrimidines are two of the building blocks of nucleic acids. Only two purines and three pyrimidines occur widely in nucleic acids. B. Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring. A purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Purines, including substituted purines and their tautomers, are the most widely distributed kind of nitrogen-containing heterocycle in nature. Aromaticity ( Kekule, Loschmidt, Thiele) is essential for the Krebs Cycle for energy production. C. Natural selection is E (energy) temporarily constrained in an m (mass) format. Natural selection is a universal ubiquitous trait of ALL mass spin formats, inanimate and animate. Life began/evolved on Earth with the natural selection of inanimate RNA, then of some RNA nucleotides, then arriving at the ultimate mode of natural selection – self replication. Aromaticity enables good constraining of energy and good propensity to hydrogen bonding. The address of Earth Life Genesis, of phasing from inanimate to animate natural selection, is Aromaticity.Hydrogen Bonding. Dov Henis (comments from 22nd century) http://universe-life.com/2012/02/03/universe-energy-mass-life-compilation/ tags: life genesis, natural selection, life mass format Dov Henis
New Era For Science Including Genomics ??? From: Dov Henis Sent: Friday, April 13, 2012 10:43 PM To: genome biologists Subject: A new era for science including genomics ??? Please examine carefully… Yesterday, SN , after many years of refusing my similar postings, SN posted my following statement-comment: http://www.sciencenews.org/index/generic/activity/view/id/339659/title/Fruit_fly_biorhythms_differ_indoors_and_out Biorhythms Schmiorythms Circadian Schmircadian sleep origin? Life sleeps because RNAs genesized, evolved from inanimate nucleotides into self-replicating nucleotides, organisms, of course long before metabolism evolved. They were then active ONLY during sunlight hours. Thus sleep is inherent for RNAs, even though, being ORGANISMS, they later adapted to when/extent sleep times are feasible just as we adapt to jetlag or night work time. Dov Henis (comments from 22nd century) Apr. 12, 2012 at 9:10am =========================== From: Dov Henis Sent: Saturday, April 14, 2012 9:05 AM To: genome biologists Subject: FW: A new era for science including genomics ??? Please examine carefully… Unbelievable?! Here’s another one… From: Dov Henis Sent: Sunday, April 08, 2012 9:06 PM To: ‘editors@sciencenews.org’ Subject: On Pavlov and genes… Fatty Diet Leads To Fat-Loving Brain Cells http://www.sciencenews.org/view/generic/id/339458/title/Fatty_diet_leads_to_fat-loving_brain_cells Learn from Pavlov: Fatty diet lead to fat-loving RNA-nucleotides genes, Earthlife base primal ORGANISMS. Dov Henis (comments from 22nd century) http://universe-life.com/2011/12/22/rnas-are-earths-primal-organisms/ =================== Since the above two statements are basis for the following statement, may it also soon pass the SN “peer review”… ?! USA Science? Re-Comprehend Origins And Essence • Higgs Particle? Dark Energy/Matter? Epigenetics? All YOK! • Earth-life is just another, self-replicating, mass format. • All mass formats follow natural selection, i.e. intake of energy or their energy taken in by other mass formats. • Evolution Is The Quantum Mechanics Of Natural Selection. • Quantum mechanics are mechanisms, possible or probable or actual mechanisms of natural selection. • Life’s Evolution is the quantum mechanics of biology. • Every evolution, of all disciplines, is the quantum mechanics of the discipline’s natural selection. See: Update Concepts-Comprehension… http://universe-life.com/2011/12/13/21st-century-science-whence-and-whither/ Earth life genesis from aromaticity-H bonding http://universe-life.com/2011/09/30/earthlife-genesis-from-aromaticityh-bonding/ Universe-Energy-Mass-Life Compilation http://universe-life.com/2012/02/03/universe-energy-mass-life-compilation/ Seed of human-chimp genome diversity http://universe-life.com/2011/07/10/seed-of-human-chimp-genomes-diversity/ ============ Respectfully, Dov Henis (comments from 22nd century) Dov Henis
On The Universe and Life Comprehensions, EOTOE (V) and (VI) EOTOE, Some Implications (v) The Gravitons Nature-Origin Puzzle My model for the EOTOE has been evolutionary biology. Since life must be just another mass format, and due to the oneness of the universe, it is commonsensical that natural selection is ubiquitous and that life, self-replication, is its extension. And it is commonsensical, too, that evolutions, broken symmetry scenarios, are ubiquitous in all processes in all disciplines and that these evolutions are the “quantum mechanics” of the processes. However, there is yet an origin of origins puzzle. Whereas the genesis of genes, life’s primal organisms, is rationally commonsensical, thus highly probably, the “naturally-selected” RNA nucleotides - the existence, origin and nature of the rationally commonsensical conjectured massed graviton are yet much farther from probable than the nucleotides life’s genesis. The gravitons are more enigmatic because science has not yet accumulated the extent and variegated considerations and examinations required to approach the comprehension of the origin of origins of the universe. PS: From http://universe-life.com/2011/12/13/21st-century-science-whence-and-whither/ notwithstanding… “The origin-reason and the purpose-fate of life are mechanistic, ethically and practically valueless. Life is the cheapest commodity on Earth. Human life is just one of many nature’s routes for the natural survival of RNAs, the base primal Earth organisms. It is up to humans themselves to elect the purpose and format of their life as individuals and as group-members.” =========================== EOTOE, Some Implications (VI) Yet something about the gravitons Yet one possible conjecture about the gravitons is that they, too, must have a dual mass-energy nature… From singularity it is a rationally commonsensical conjecture that they are a mass format, the smallest elementary mass particles. Nevertheless from the Big-Bang it is a rationally commonsensical conjecture that they must also be energy, i.e. mass in motion, even at singularity. This is rationally commonsensical since otherwise the Big would not Bang… This raises the origin of origins puzzle to an unknown power… Dov Henis (comments from 22nd century) http://universe-life.com/2011/12/10/eotoe-embarrassingly-obvious-theory-of-everything/ Dov Henis
Gee... in all of that it was never explained how observed immaterial qualities came to the instantiated in tRNA/aaRS. It's kind of important, since life and evolution depend upon it. Upright BiPed
EVERYTHING in the universe evolves by natural selection: An Embarrassingly Obvious Theory Of Everything I. EOTOE, Some Implications (I) A. EOTOE is an Embarrassingly Obvious Theory Of Everything. In essence it states that all things in the universe, nouns and verbs objects and processes, originate and derive from the energy-mass dualism. Origin and essence of this derivation are expressed mathematically by E=Total[m(1+ D)] (D = distance travelled by mass since singularity) Which suggests that the universe cycles between two poles: singularity/all-mass , and maximum-expanded/nearly-all-energy. The “nearly” all-energy leaves behind some mass formats that begin consolidating by gravity, when it eventually overcomes expansion as the mass fueling the expansion is nearly depleted, becoming very small m multiplied by very large D = E . B. Thus the essence/definition of gravitation is: “Gravitation Is the propensity of energy reconversion to mass”. Gravitation is the “monotheism” and the “ genesis” of the universe. Singularity, at D = 0, is the very brief all-mass pole of the universe. The Big-Bang-inflation did not produce matter or anti-matter. It was the beginning of mass reconversion into energy, of increasing D fueled by decreasing m. The conjectured gravitons, smallest basic particles, most probably do exist, but must be with mass, and gravitons microclusters must “big-bang” during the on-going expansion at a resolution of their energy-mass superposition. This is rationally commonsensical, therefore it is scientifically probable. Inflation started with the whole universe m shattering into fragments that evolved into, became, the galaxy clusters. The clusters expansion is fed at a constant rate by m-fuel. Since expansion accelerates, since the clusters depart from each other at an ever increasing velocity, we learn that the rate of m-to-E reconversion in the universe is constant. The accelerated expansion derives from the ever decreasing m of each cluster. C. Thus the essence/definition of evolution, natural selection is: Mass formats attaining temporary augmented energy constraint in their successive generations, with energy drained from other mass formats, to temporarily postpone, survive, the reversion of their own constitutional mass to the pool of cosmic energy fueling the galactic clusters expansion. This explains why black holes and humans, in fact all mass formats, must feed themselves in order to survive. This explains that the essence of quantum mechanics of all processes is the detailed procession steps, the evolution details, between physical states ordained for natural selection. D. Thus comes to light the universe inspected progressively in greater detail. Science reveals the universe’s nature-scope and directing drive, followed by technology studying its evolution details-aspects, followed by engineering exploitation of the attained information. This suggests the specific weight, importance, of science, technology and engineering in considering of research or enterprise plans and implementation. Dov Henis (comments from 22nd century) http://universe-life.com/ PS1: Definitely: Dark energy and dark matter YOK! Universe's m reconverts to E at a constant rate… Universe accelerated expansion is per Newton's motion laws, obviously… Also, universe physics constants should vary, probably slightly, between galaxies clusters due to different clusters sizes... Also, the clusters formed by dispersion at inflation… PS2: The singularity constituents must have been the smallest elementary particles. They may be designated gravitons, but they MUST HAVE MASS. They were born at the energy-mass superposition resolution, together with the fragments that became galaxies clusters. At expansion D increases, therefore m decreases, which per Newton mandates mass and matter acceleration. This goes on, most probably, at a constant rate of mass-to-energy reconversion, at an energy-mass resolution, mandated by the equality of both sides of the top equation.. And this resolution is, for each graviton, most probably in a format of a minuscule big-bang. This is a lesser fantasy than the dark matter and energy fantasy. Such mass-energy gravitons may be omnipresent within each galaxies cluster, maintaining each cluster as a primordial Newtonian body and being the fuel-driver of expansion. II. EOTOE, Some Implications (II) This equation describes the presently expanding universe: E=Total[m(1 + D)] D = distance travelled by mass since singularity This equation describes the future contracting universe: E=Total[m(1 + D)] D = reduced expansion distance travelled by mass in the preceding expansion phase Implications: The base units of mass - may be designated gravitons but MUST have mass - are not temporal, they never disappear. In the present expanding universe they are in motion as mD away from the singularity point. Those of them that hit a whatever mass format and move it become inert. This will go on until all or nearly all of them cease moving forward, i.e. until D ceases growing. When D ceases growing gravitation will overcome the inertial motion away from the singularity point and will start pulling them back towards it. It is then that D will start diminishing, to maintain the equation’s equality… And MORE, MUCH MORE: The rational commonsensical, and therefore scientifically probable, implication is that Space is imbued with these massed gravitons that are continuously left behind during Expansion… also as micro clusters sized between gravitons and neutrinos… III. EOTOE, Some Implications (III) Classically: Energy = dynamic quality, the capacity of acting or being active, a fundamental entity of nature that is transferred between componentsts of a system in the production of physical change within the system and usually regarded as the capacity for doing work. Mass = Mass is the quantity of inertia possessed by an object or the proportion between force and acceleration referred to in Newton’s Second Law of Motion. Per EOTOE : E=Total[m(1 + D)] D = distance travelled by mass since singularity Energy is mass in motion. The mass of the universe is either in motion or in the form of inert massed gravitons, with which the universe is imbued. m of the EOTOE equation is only the energetic m, the m which is in motion. The inert gravitons do not play a role in the E,m,D relationship. At the (present) universe expansion phase mass reconverts to energy at a constant rate, leaving behind inert gravitons. Inert gravitons become energetically active when they are reset in motion, i.e. when acted upon by energy, such as by gravity during the universe re-contraction phase. Dov Henis (comments from the 22nd century) http://universe-life.com On Light And Dark Mass And Energy http://universe-life.com/2011/10/03/on-light-and-dark-mass-and-energy/ IV. EOTOE, Some Implications (IV) This equation describes the future contracting universe: E=Total[m(1 + D)] D = reduced expansion distance travelled by mass in the preceding expansion phase Elaboration and conjectured implications: D is the distance travelled by mass in all spatial directions emanating from the Big-Bang singularity point. During contraction it decreases, accompanied with increasing m effected by the constant E. A commonsensible conjecture is that contraction is initiated following the Big-Bang event, steadily re-forming the Universe Singularity simultaneously with the inflation and expansion, i.e. that universal expansion and contraction are going on simultaneously. Additional conjectured implications are that the Universe is a product of A Universal Black Hole with a Singularity consisting of mass gravitons, and that gravitation is a weak force due to the graviton’s size. Dov Henis (comments from the 22nd century) http://universe-life.com/2011/10/07/eotoe-some-implications-i/ http://universe-life.com/2011/10/14/eotoe-some-implications-2/ http://universe-life.com/2011/10/26/eotoe-some-implications-iii/ Dov Henis
On trade-union science, whence and whither... Imagine, just imagine, the interest and activity big bang in science if/when finally freed from AAAS stock !!! Science is not another, AAAS trade-union peer-reviewed, religion. It takes continuously critical refreshed thinking.... Whence And Whither Extend Darwin-Einstein Horizon, EmD EmD versus Emc http://dovhenis.wordpress.com/2011/06/23/emd-versus-emc/ E = mc2 relates E and m via constant c. However, since E and c are constant m must also be constant…?! Yet for engineering-technology applications the equation is practical, fine. E=Total[m(1 + D)] relates E and m via the variable D. D is the sum total of distance, in ALL spatial directions, travelled by m since start of reconversion of m to E. This relationship is science, not engineering or technology. E is constant, m and D are variables. D cannot be less than zero, and m varies with D. This is universal reality. In this reality there is no missing E. E is there, transformed to mD. mD is E. In this reality there is no missing m. m is there, transformed to mD. mD is E. Think about it. This is the basis-essence of Evolution, of ALL evolutions. Evolutions are the quantum mechanics of all processes. Dov Henis (comments from 22nd century) http://universe-life.com ------------------------------------- “how species come to be…” http://www.sciencenews.org/index/feature/activity/view/id/331382/title/Evolution%E2%80%99s_Wedges http://dovhenis.wordpress.com/2011/07/06/evolution-how-species-come-to-be/ What drives “species come to be” is what drives all life/organisms to come to be, i.e. a proven successful route, circumstantially evolved culture, that enhanced the RNAs’ constrained energy by the culturally enhanced RNAs’ proliferation, followed with accordingly alternatively spliced expression. This is evolution, i.e. enhanced constrained energy to delay-postpone the universal conversion of mass-formats to energy, to the energy that keeps fueling the expansion of the universe. This expansion will be overcome by gravity upon depletion of the universe’s massfuel, and will be followed by empansion for accelerating reverting of energy to mass all the way back to singularity. The universe is an allmass allenergy poles affair. Dov Henis (comments from 22nd century) http://dovhenis.wordpress.com/2011/07/10/seed-of-human-chimp-genomes-diversity/ PS: - It's culture that modifies genetics, that changes gene's expression. NOT vice versa. - Epigenetics YOK. Alternative splicing is epiDNAtic, not epigenetic. - ALL life is RNAs evolution products. RNAs are Earth's prime organism. DH ======================== Update Comprehension Of Universe/Life Evolution, Of RNA/DNA Mismatch-Relationship http://dovhenis.wordpress.com/2011/06/10/update-comprehension-of-universelife-evolution/ Genome is evolved by-for RNAs, like all other Earth organisms: THE National Science And Technology Policy ISSUE In The USA (And Therefore Elsewhere...): The early 20th century brief burst of scientific evolution started expiring 90 years ago, at the birth of the "scientists" (what does this mean?) trade-union AAAS. True to the AAAS trade-union interests the scientific evolution has grown into the technology-industrial evolution, with evolved counter-enlightenment, greed culture. Re Science Education, it's about WHAT, not about HOW, is taught. "Scientists" tradeunion-politically-controled "science" cannot be advanced/updated regardless of education system... See the C signature link... Unravel Some Of Nature's Complexities, A + B + C (adnauseam, ad shown where these data-based statements are wrong) A. UNRAVEL COMPLEXITIES OF GENETICS. Extend Evolution/Natural Selection Backward To Genes/Genomes, BOTH ARE ORGANISMS. Again, Correct Some Figments Of Science Imagination: 1. Dark energy and matter YOK. Per E=Total[m(1 + D)] all the energy and matter of the universe are accounted for. Adopt space-massdistance concept, mass-to-energy reconversion. 2. Higgs Particle YOK. Mass forms below some value of the above D. 3. Galactic clusters formed by conglomeration? Galactic clusters formed by Big-Bang's dispersion, evidenced by their Newtonian behaviour including expansion acceleration. 4. The universe expansion is fueled by the mass-to-enrgy reconversion. Eventually, as expansion will slow down, will run out of massfuel, gravity will overcome expansion and initiate empansion back to singularity. The universe is a cyclic array of energy-mass dualism, between all-energy and all-mass poles, under omnipresent gravity. 5. Natural Selection is a trait of organisms, life? No. Natural selection is ubiquitous for ALL mass formats, all spin arrays. It derives from the expansion of the universe. All mass formats, regardless of size and type, from black holes to smallest particles, strive to increase their constrained energy in attempt to postpone their own reconversion to energy, to the energy that fuels cosmic expansion. 6. Life is an enigma? Life is just another type of mass array, a self-replicating mass array. Earth life is a replicating RNAs mass. It has always been and still is an RNA world. ALL Earth's organisms are evolved RNAs, evolved for maintaining-enhancing Earth's biosphere, for prolonging RNAs survival. 7. Cells are Earth-life's primal organisms? NO. Earth's life day one was the day on which RNA began replicating. RNAs, genes, are ORGANISMS. And so are their evolved templates, (RNA and DNA) genomes, ORGANISMS, as evidenced by life's chirality and by life's sleep. 8. Circadian Schmircadian sleep origin? Sleep is inherent for life via the RNAs, the primal Earth ORGANISMS originated and originally active only under direct sunlight, in their pre-metabolism genesis era. 9. Epigenetics are heritable gene functions changes not involving changes in DNA sequence? The "heritable or enduring changes" are epiDNAtics, not epigenetics. Alternative splicing is not epigenetics, even if/when not involving alteration of the DNA sequence. Earth life is an RNA world. 10.Genetics drive biology and culture modifications? NO. It is culture that modifies genetics, not genetics that modifies culture. Culture modifies genetics simply via the evolutionary natural selection process of the RNA ORGANISMS. Likewise many natural genetic changes are due to aging and/or circumstantial effects on the genes and/or genomes ORGANISMS, similar to aging and/or evolutionary processes in monocell communities or in multicelled organisms. SCIENCE SHOULD UNFREEZE. SCIENCE SHOULD ADJUST ITS VISION, COMPREHENSION AND CONCEPTS. Dov Henis (Comments From 22nd Century) Seed of Human-Chimp Genomes Diversity http://dovhenis.wordpress.com/2011/07/10/seed-of-human-chimp-genomes-diversity/ 03.2010 Updated Life Manifest http://dovhenis.wordpress.com/2011/07/13/03-2010-updated-life-manifest/ Evolution, Natural Selection, Derive From Cosmic Expansion http://darwiniana.com/2010/09/05/the-question-reductionists-fear/ Rethink Evolution/Natural Selection http://darwiniana.com/2011/03/29/comment-from-dov-henis/comment-page-1/ ========================== B. Quantum Mechanics Of Life Life's Evolution Is The Quantum Mechanics Of Biology http://universe-life.com/2011/03/27/quantum-mechanics-of-life/ http://universe-life.com/2011/01/24/quantum-mechanics-and-entanglement/ The universe, and life within it, are not just conglomerations of mechanisms. The universe, and life within it, have come into being by the nature of energy-mass dualism, and their fate, their final outcome, is governed by this dualism. The genesis and, most probable cyclic, existence of the universe are governed by the energy-mass relationship. Energy-mass relationship governs also the routes, the mechanisms, of cosmic and life evolutions. Mechanisms do not set/determine the classical physics fate states. Mechanisms are routes of evolution between classical physics fate states. Quantum mechanics are mechanisms, probable, possible and actual mechanisms of getting from one to other classical physics states WITHIN the expanse from cosmic singularity to the maximum expanded universe and back to singularity states. The universe is the archetype of quantum within classical physics. This is the fractal oneness of the universe. Astronomically there are two physics. A classical Newtonian physics behaviour of and between galactic clusters, and a quantum physics behaviour WITHIN the galactic clusters. Life's Evolution Is The Quantum Mechanics Of Biology. UNRAVEL COMPLEXITIES OF GENETICS. Extend Evolution/Natural Selection Backward To Genes/Genomes. BOTH ARE ORGANISMS. The origin-reason and the purpose-fate of life are mechanistic, ethically and practically valueless. Life is the cheapest commodity on Earth. Human life is just one of many nature's routes for the natural survival of RNAs, the base Earth organism. It is up to humans themselves to elect the purpose and format of their life as individuals and as group-members. Dov Henis (Comments From 22nd Century) Inception And Prevalence Of Western Monotheism http://darwiniana.com/2011/04/20/comment-on-old-testament/ ============================= C. Adaptation And Genetics Identify USA Science Problems Enough Is Enough! Concluding phrase of "A New Evolutionary History of Primates" http://www.sciencedaily.com/releases/2011/03/110317172047.htm "genetic underpinnings of human adaptation" This phrase displays basic ignorance of the relationship between genetics and physiology/system adaptation. It should be replaced with "adaptation underpinnings of human genetics". UNRAVEL COMPLEXITIES OF GENETICS. Extend Evolution/Natural Selection Backward To Genes/Genomes, BOTH ARE ORGANISMS. IT IS ADAPTATION (CULTURE) THAT INDUCES GENES' EXPRESSION MODIFICATION, NOT GENETICS THAT INDUCES ADAPTATION. Modified genetic expression proceeds to energetically favor/enable adaptation. Dov Henis (comments from 22nd century) http://universe-life.com/ http://universe-life.com/2011/01/25/hope-for-2011-science/ http://dovhenis.wordpress.com/2011/07/12/prsdnt-obama-academy-help-is-not-aaas-help/ http://universe-life.com/2006/03/13/science-creed-manifest-scm/ PS: How have the USA government and nation/public come to allow a plainly obvious ("scientists", whatever it means) trade-union, AAAS, to be involved in a host of national policies and budgets matters? The motives/interests of the AAAS, just another trade-union, are NOT always/necessarily congruent with the nation's/public welfare and it definitely hinders very effectively advancement of basic science...DH Dov Henis
First Let’s Learn What Life And Genes Are: (Extend evolution way down to genes, life’s base ORGANISMS. Culture modifies genetics, not vice versa...) Pavlov’s Smile: RNAs Are Earth’s Primal Organisms Culture>genes>addiction (2 July 2009) http://universe-life.com/2011/09/24/pavlovs-smile/ Why Pavlov smiled in 2008? Pavlov demonstrated effecting placebo phenomena in multi celled organisms by manipulation of their drives-reactions. Now placebo and imagination phenomena are demonstrated also in Earth’s smallest, base organisms, in the genes and genomes of multi-celled organisms, in our primal 1st stratum and 2nd stratum base organisms. A very good reason to smile. Now an interesting chain is exposed to our view, the Genes-Virtual Reality Chain, a most intriguing cultural evolution chain extending from the genesis of our genes to nowadays, throughout life, a virtual reality existence, and by virtual reality phenomena, exploitations and manipulations. Dov Henis (comments from 22nd century) http://universe-life.com From “Life Genesis From Aromaticity/H-Bonding” http://universe-life.com/2011/09/30/earthlife-genesis-from-aromaticityh-bonding/ Natural selection is E (energy) temporarily constrained in an m (mass) format. Natural selection is a universal ubiquitous trait of ALL mass spin formats, inanimate and animate. Life began/evolved on Earth with the natural selection of inanimate RNA, then of some RNA nucleotides, then arriving at the ultimate mode of natural selection, self-replication. Dov Dov Henis

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