From Your ORFans Cheerleader
Just a couple of links to enliven your morning… This Science Daily story describes a paper from the latest PLOS Biology, on the role of ORFans in generating species-specific traits in animals. Konstantin Khalturin and his co-authors at the Christian-Albrechts-University in Germany note the “substantial fraction” of ORFans — genes without known homologs — in every genome thus far sequenced, and argue that the origin of unique morphologies may rest in part with these unique genes: Understanding the molecular events that underlie the evolution of morphological diversity is a major challenge in biology….All genome and expressed sequence tag (EST) projects to date in every taxonomic group studied so far have uncovered a substantial fraction of genes that are without known Read More ›

