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Darwinism and the breakdown in communications

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From ScienceDaily:

Japanese researchers from Osaka University have uncovered a way in which our cells regulate the repair of broken DNA. Their results, published in the journal “Cell Reports,” show a common molecule regulates multiple repair mechanisms and help shed light on how the cell maintains the integrity of the human genome when it is damaged.

The human body consists of trillions of cells, and within each are billions of DNA molecules. Strict maintenance of the molecules is essential to maintain a healthy cell and thus a healthy body.

This maintenance is challenged by the daily bombardment of chemicals, UV light, radical oxgen and radiation that can damage the DNA molecules. If left unrepaired, the damage could lead to genomic instability and cell death. Thankfully, evolution has created in the cell innate repair mechanisms to fix any damaged DNA. Paper. (public access) – Shin-Ya Isobe, Koji Nagao, Naohito Nozaki, Hiroshi Kimura, Chikashi Obuse. Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair. Cell Reports, 2017; 20 (2): 297 DOI: 10.1016/j.celrep.2017.06.056 More.

Note: “Thankfully, evolution has created in the cell innate repair mechanisms to fix any damaged DNA.” If “Evolution” “has created” these innate repair mechanisms, it must be functioning as some kind of an intelligent force.

Note also the assumption just shoved under the rug here: Life forms seek to repair themselves.

Inanimate objects do not seek to repair themselves. What is the nature of the difference between life and non-life that life seeks to continue in its live, healthy state? More, the mere fact that a life form would like to repair itself does not mean that it will have a repair kit handy. That is a separate issue that can’t be papered over by throwaway remarks such as “evolution has created…” Words should mean something.

These researchers should just go ahead and do their work, but we need to see that Darwinian assumptions are breaking down under the weight of  the language  nlanguage needede these situations.

See also: The “beautiful mechanism” by which an egg becomes an embryo

and

What can we hope to learn about animal minds?

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Comments
Thankfully, evolution has created in the cell innate repair mechanisms to fix any damaged DNA
There's another oddity in this: undamaged DNA kept getting damaged, so evolution damaged it some more and things got better.Jon Garvey
July 19, 2017
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The dogma of evolution is anti-science.tribune7
July 18, 2017
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The reason for the different HDR reporter assay results in the two studies remains unknown [...] It will be interesting to determine the 53BP1-independent function and regulation of SCAI. [...] it is important to identify the kinases responsible for phosphorylation of S/TP sites. The involvement of Plks in the regulation of pathway selection through 53BP1 phosphorylation should be investigated in a future study. Our initial characterizations of SCAI function in DNA repair, along with those by Hansen et al. (2016)), will stimulate future experimental analyses for understanding the regulation of these robust and flexible repair pathways.
Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair Shin-Ya Isobe, Koji Nagao, Naohito Nozaki, Hiroshi Kimura, Chikashi Obuse DOI: http://dx.doi.org/10.1016/j.celrep.2017.06.056 Cell Reports Volume 20, Issue 2, p297–307
Complex, functionally specified informational complexity. :)Dionisio
July 18, 2017
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DNA double-strand breaks (DSBs) are repaired by either the homology-directed repair (HDR) or the non-homologous end-joining (NHEJ) pathway. [...] the molecular mechanism underlying pathway choice remains unclear. [...] SCAI inhibits RIF1 function to allow BRCA1-mediated repair, which possibly includes alt-NHEJ and resection-dependent NHEJ in G1, as well as HDR in S/G2.
Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair Shin-Ya Isobe, Koji Nagao, Naohito Nozaki, Hiroshi Kimura, Chikashi Obuse DOI: http://dx.doi.org/10.1016/j.celrep.2017.06.056 Cell Reports Volume 20, Issue 2, p297–307
Complex, functionally specified informational complexity. :)Dionisio
July 18, 2017
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Evolution evolved to prevent evolution. Makes sense to me.Mung
July 18, 2017
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