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Function, the evolution-free gospel of ENCODE

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There is no better title for this post than the very title some Darwinists chose for themselves:

On the immortality of television sets: “function” in the human genome according to the evolution-free gospel of ENCODE

Darwinists are still struggling to come to terms with the idea, from the ENCODE project, that 80% of the genome is functional. Whatever Dawkins now says, according to their model, only about 10% should be subject to natural selection, leaving 70% unexplained. This cannot be!

Apparently, ENCODE are to be criticised for using an ‘evolution-free’ definition of function. Yep, you heard that right. You thought that function was function was function, but oh no, you must use a evolution-y definition or you will not get the ‘correct’ evolution-y answer. It seems awfully like you need to presuppose Darwinism or you will not find Darwinism. Can that be right?

The excuse for this is some interesting Darwinian philosophy (or do I mean sophistry? – make up your mind below): the authors believe that function means nothing (is purely subjective) unless it is selected for. For example, the heart causes the pericardium (the membrane around the heart) to not collapse by filling space, so we could call that a function, but it is selected for pumping blood.

Well, yes, that’s an interesting point, and that’s where it ends for a Darwinist because Darwinists resist the possibility of purpose. But it is nonsense to an engineer. An engineer would not make the mistake of seeing the pericardium as more important than the heart. A broken watch may still contain many functional components even if overall it does nothing. A TV switched off is still a TV even if it never functions. Is that subjective?

It depends what you mean by subjective. If your only ultimate reference frame is physics (and biology as a derivative of physics), then of course all intelligent agents are in fact subjective! For much of what we know, never mind religion and ethics, even in something solid like the definition of a motor, there is no way of translating it into physical equations (you could describe an instance of a motor but that would not capture all possible motors or what ‘motorness’ is – physics makes motors work but it doesn’t know what they are). However, what if all intelligent agents shared that ‘subjective’ knowledge? Then it isn’t really subjective anymore is it? At very least, a being that knows what a motor is, or that a bacterial flagellum is a motor, is more intelligent than one that does not. When we say there is an intelligence out there, we mean there must be a being like us in this respect. A being who wouldn’t be so stupid as to think that the heart was put in to hold up the pericardium. We might not be able to explain why that is stupid, but that doesn’t stop it from being objectively stupid. See my point? Darwinians effectively deny intelligence full stop, writing it off as subjectivity.

Amongst other things the ENCODE authors are lambasted for not distinguishing between ‘Junk DNA’ and ‘Garbage DNA’. No seriously, ‘junk’ now means stuff that is functional, but not used very often, but could be used, like stuff in your attic is ‘junk’. It is different from ‘garbage’, which is the stuff that you would put straight in the bin. ‘junk’ is now a rather misleading word for ‘functional’. So our genome is full of ‘junk’ that is useful and functional, but to a Darwinian it does not count until it starts getting used so that natural selection can get the credit. How convenient! The possibility of design is sidestepped by careful choice of language. Welcome to 1984! A better word might be ‘archived’ rather than ‘junk’.

This article tells us a lot about what is wrong with the whole project. The way to find out if the genome is functional or not, is to look directly for actual function. No presuppositions, just objectivity. But they criticise the attempts of ENCODE to do that. Instead these guys are focussing on searching for indirect evidence of natural selection, with models replete with assumptions and complexities, all presupposing that Darwinism is true. If the Darwinist approach was followed (thankfully many scientists ignore it!) the simple question “functional or not?” could potentially get buried for decades more, under the continuing assumption that most is not. A few more valuable decades in which Darwinists tell us not to bother go looking for function, so slowing down scientific progress.

I, and many of us, hold to an ID worldview firstly and most securely because of what we know about prebiotic chemistry and thus the origin of the first life form. Based on that, because I know there has been a designer involved, I think probably a lot of ‘junk’ will turn out to be ‘brought down from the attic’ at various stages of an organisms life, especially in the developing stages. Time will tell.

Scientific means finding out what is actually there. ENCODE are to be praised for doing that. Darwinism has always been about telling creation myths from the point of view of naturalism (roughly, physics only), and shoehorning every fact into the story. ENCODE are now receiving scorn because they did not wait for the Darwinian imprimatur. Intelligent Design people and creationists (in fact everyone who is not a Darwinist) should take courage from this, jump in and start driving forward ordinary mainstream science, but just make sure they sidestep the attempts to sign them up to that cult.

Comments
wd400, I'm just trying to square your belief that the majority of sequences are non-functional (merely transcribed) with the unfathomed complexity being revealed in the cell. For instance:
DNA - Replication, Wrapping & Mitosis - video http://vimeo.com/33882804 Unwinding the Double Helix: Meet DNA Helicase - Jonathan M. February 20, 2013 - article with video Excerpt: With a rotational speed of up to 10,000 rotations per minute, the helicase rivals the rotational speed of jet engine turbines. http://www.evolutionnews.org/2013/02/unwinding_the_d_1069371.html Harvard Scientists Write the Book on Intelligent Design—in DNA - Dr. Fazale Rana - September 10, 2012 Excerpt: One gram of DNA can hold up to 455 exabytes (one exabyte equals 10^18 bytes). In comparison, a CD-ROM holds about 700 million (7 x 10^8) bytes of data. (One gram of DNA holds the equivalent amount of data as 600 billion CD-ROMs. Assuming a typical book requires 1 megabyte of data-storage capacity, then one gram of DNA could harbor 455 trillion books.) http://www.reasons.org/articles/harvard-scientists-write-the-book-on-intelligent-design-in-dna The data compression of some stretches of human DNA is estimated to be up to 12 codes thick (12 different ways of DNA transcription) (Trifonov, 1989). (This is well beyond the complexity of any computer code ever written by man). John Sanford - Genetic Entropy DNA - The Genetic Code - Optimal Error Minimization & Parallel Codes - Dr. Fazale Rana - video http://www.metacafe.com/watch/4491422 'Quadruple helix' DNA discovered in human cells - January 20, 2013 Excerpt: In 1953, Cambridge researchers Watson and Crick published a paper describing the interweaving 'double helix' DNA structure - the chemical code for all life. Now, in the year of that scientific landmark's 60th Anniversary, Cambridge researchers have published a paper proving that four-stranded 'quadruple helix' DNA structures - known as G-quadruplexes - also exist within the human genome.,,, Physical studies over the last couple of decades had shown that quadruplex DNA can form in vitro - in the 'test tube', but the structure was considered to be a curiosity rather than a feature found in nature. The researchers now know for the first time that they actually form in the DNA of human cells. "This research further highlights the potential for exploiting these unusual DNA structures to beat cancer –,,, "It's been sixty years since its structure was solved but work like this shows us that the story of DNA continues to twist and turn.",,, While quadruplex DNA is found fairly consistently throughout the genome of human cells and their division cycles, a marked increase was shown when the fluorescent staining grew more intense during the 's-phase' - the point in a cell cycle where DNA replicates before the cell divides.,,, It's a philosophical question as to whether they are there by design or not - but they exist and nature has to deal with them.,,, "The 'quadruple helix' DNA structure may well be the key to new ways of selectively inhibiting the proliferation of cancer cells. The confirmation of its existence in human cells is a real landmark." http://phys.org/news/2013-01-quadruple-helix-dna-human-cells.html Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome - Oct. 2009 Excerpt: At the megabase scale, the chromatin conformation is consistent with a fractal globule, a knot-free, polymer conformation that enables maximally dense packing while preserving the ability to easily fold and unfold any genomic locus. http://www.sciencemag.org/cgi/content/abstract/326/5950/289 3-D Structure Of Human Genome: Fractal Globule Architecture Packs Two Meters Of DNA Into Each Cell - Oct. 2009 Excerpt: the information density in the nucleus is trillions of times higher than on a computer chip -- while avoiding the knots and tangles that might interfere with the cell's ability to read its own genome. Moreover, the DNA can easily unfold and refold during gene activation, gene repression, and cell replication. http://www.sciencedaily.com/releases/2009/10/091008142957.htm Biochemical Turing Machines “Reboot” the Watchmaker Argument - Fazale Rana - July 2012 Excerpt: Researchers recognize several advantages to DNA computers.(7) One is the ability to perform a massive number of operations at the same time (in parallel) as opposed to one at a time (serially) as demanded by silicon-based computers. Secondly, DNA has the capacity to store an enormous quantity of information. One gram of DNA can house as much information as nearly 1 trillion CDs. And a third benefit is that DNA computing operates near the theoretical capacity with regard to energy efficiency. http://stevebrownetc.com/2012/07/02/biochemical-turing-machines-%E2%80%9Creboot%E2%80%9D-the-watchmaker-argument/ etc.. etc.. etc..
I just don't see where the presupposition of non-functional sequences in the DNA is justified wd400. It, the presupposition, certainly is not fruitful to spurring further research, and from what I can tell, the necessity of the presupposition arises solely from the neo-Darwinian framework i.e. genetic reductionism. A framework that is fairing none to well these days. Shoot, as if all the preceding was not bad enough to your presupposition that 'filtered accidents' can build unfathomed complexity, I think you guys are about to lose the the 'concept of a gene' entirely!
Landscape of transcription in human cells – Sept. 6, 2012 Excerpt: Here we report evidence that three-quarters of the human genome is capable of being transcribed, as well as observations about the range and levels of expression, localization, processing fates, regulatory regions and modifications of almost all currently annotated and thousands of previously unannotated RNAs. These observations, taken together, prompt a redefinition of the concept of a gene. http://www.nature.com/nature/journal/v489/n7414/full/nature11233.html
bornagain77
February 24, 2013
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JGuy, The 10^-9 mutation rate that is often cited is an estiamte of the rate per nucleotide per generation. In Ohno's time we couldn't get that sort of resolution, so he was talking about the rate per locus per generation. If the exonic bits of an average locus is 3,000 bp then that's a 1e-6 mutation rate per locus. If most mutations are harmless of no consequence the 1e-5 sounds about right. When Ohno was developing these idea evolutionary biologists where a lot more Darwinian than we are today, and though that pretty much everything in the genome would be there for some reason. Ohno was saying that's not possible. Subsequent studies have vindicated him, and, unless you really think transcription is a function then ENCODE does little to change that.wd400
February 24, 2013
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wd400 I'm not an expert in this area, but I see some things as obvious enough. Perhaps, I'm mistaken. Ifso, so-be-it. But I was hoping you would have come to the same thought... Question: Would Ohno's paper have come to a different conclusion regarding the "junkness" of 94% of the DNA if the mutation rate was 10^-9 instead of 10^-5? My thinking is that: Yes, he would have. Why? Because if that is true, that he would have had a different conclusion, then it seems obvious enough (to me at least) that he is avoiding/circumventing the problem, not in conspiracy, but in the sense that he is assuming there actually should be no problem b/c all that other stuff must be junk at the given mutation rate.JGuy
February 24, 2013
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JGuy posted this:
Selection is good at destroying and removing genetic sequences.
No it isn't. Selection does not act on sequences, it acts on bodies. If the sequence isn't expressed in the phenotype, then the sequence can't be selected for or against.timothya
February 24, 2013
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There is nothing slippery about Darwinism, it's a word with a meaning. Creationists use it as a stand in for evolutionary biology, presumably because it's easier to fight and -ism than an entire field of study. This example proves the point, as many materialists biologists are unhappy with our junky genome and are always looking for ways to add more function. JGuy, You still haven't told me what porblems Ohno was avoiding in using the term junk.wd400
February 24, 2013
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Wow. Just wow. 20 comments in and still nothing from our friends on the other side...englishmaninistanbul
February 24, 2013
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@wd400 comment 14 Like 'evolution', 'Darwinism' is a slippery word. Here it is used for the grand narrative of materialism in biology. That is what Darwin pioneered and why he made such an impact. Natural selection in itself is a trivial concept. His idea was that it could do and had done a lot of creative work. Transcription might not necessarily be function, but it was a surprise to people who were thinking according to the Darwinian big picture. Only 'stupid' people like us expected a lot more activity in the genome, rather than inert junk. To be fair, it remains to be seen how much of this material is truly functional now, especially in embryos, how much could trivially be switched on to become functional (like archived material), and how much is genuinely damaged or useless 'garbage'. Darwin and Intelligent Design continue to make opposite predictions in that regard. Who will win? Time will tell.andyjones
February 24, 2013
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The link wasn't sent to critique a website, but to see scanned paper of Ohno's. In fact, it's easy to find, the paper consumes ~95% of the page while ~5% of the web page is so called junk. :)JGuy
February 24, 2013
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That site appears to be the collected ravings of madman, but there is no sign of the "obvious problem" Ohno was avoiding in using the term 'junk'.wd400
February 23, 2013
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http://www.junkdna.com/ohno.htmlJGuy
February 23, 2013
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How much energy would a cell be wasting then? Hardly any. Especially not comparing one junky-genome to another (the evolutionary process doesn't, after all, allow us to compare with a 'prefect' state, only what exists in a given generation). What "obvious problem" was Ohno avoiding in calling this DNA 'junk'?wd400
February 23, 2013
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But, doesn’t anyone want to tackle the actual critique of ENCODE’s magic number? Is transcription really a function? Is there any good reason to say transcription is a function and DNA replication isn’t (other than that would leave us with a 100% functional genome)
Assume for a moment that 95% of the DNA was junk as Dawkins et.al. have said and assumed. How much energy would a cell be wasting then? Suppose it can be shown that an organism would only need to consume 1/10th as much of the available resources of the environment to survive. I'd say that would be a pretty serious advantage. But the need for less energy would not be the only advantage: the organisms strength to weight ratio would be greater than it's dense counterpart, and the organisms speed & agility would both be greater... among potentially other possible benefits. Selection is good at destroying and removing genetic sequences. So, wouldn't selection travel an easily found path to remove the useless portions? In that case, if it can be shown that so much energy would be saved, then how can it be possible that it is still there and not selected? Saying that, well it's there..would of course not be an explanation. And invoking chance would not make sense given the ease we would expect such junk to be removed. Dawkins said he thinks Darwinist would hope to find function, but that is bologna..who would hope to find more complexity in a problem? The reason it was called junk was to avoid obvious problems - as noted above in comments and in linked source. In the recent video posted on UD, Behe made a strong point regarding this, where he shows that finding solutions that destroys to the end that an organism gained beneficial resistance to malaria was always the case, and added that no examples are found where there was a non destructive solution.JGuy
February 23, 2013
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I don't much like the Graur et al. article, because the silly tone of it lets people gloss over the more substantive criticisms. But, doesn't anyone want to tackle the actual critique of ENCODE's magic number? Is transcription really a function? Is there any good reason to say transcription is a function and DNA replication isn't (other than that would leave us with a 100% functional genome) This is also another case when this verbal-tic of calling evolutionary biology "Darwinism" looks particularly stupid - junk DNA, after all, arises because of the weakness of natural selectionwd400
February 23, 2013
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Pav @ 11 & 12. Excellent comments! Makes me wonder if Darwinist actually regret the discovery of DNA. :D And I see that "push-back" isn't just the name of another dieting plan.JGuy
February 23, 2013
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Here's a quote from Stomatoyannoupolos' article that Graur, Zheng, et. al., find so objectionable. At the outset of ENCODE in 2003, it was widely assumed that evolutionary conservation would prove to be the ultimate arbiter of functional elements in the human genome sequence—all that was lacking was a sufficiently deep sampling of vertebrate genomes for comparative analysis. Correspondingly, highly conserved noncoding sequences were frequently equated with regulatory DNA. For a variety of reasons, both of these expectations missed the mark widely. Following on studies of transcriptional regulation in the RET locus (Fisher et al. 2006), The ENCODE Pilot Project raised a general alarm: Most elements defined by biochemical signatures lacked strong evolutionary conservation (The ENCODE Project Consortium 2007). Conversely, most highly conserved elements escaped annotation using biochemical or other functional assays (Attanasio et al. 2008; McGaughey et al. 2008; Taher et al. 2011). These initial findings have been considerably amplified by the vast volume of data accumulated during the current production phase (The ENCODE Project Consortium 2012) and by other functional studies (Blow et al. 2012). IOW, this is "population genetics" standing on its head! Now we know the reason for the push-back.PaV
February 23, 2013
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The ENCODE project has the possibility of demolishing population genetics, and with it, neo-Darwinism. Such a demise would render Darwinism hollowed-out. That is what the authors are pushing back against in their critique of ENCODE. Two articles removed (and it's free) is an article whose coauthor is John Stomatoyannoupolos. He apparently is the "villian" in all of this. Here's what they report : Our results demonstrate that regulatory variation is pervasive throughout the genome, on average mildly deleterious, and individuals likely harbor more functionally important variants in noncoding compared with protein-coding DNA. The bolded section is the true blasphemy Stomatoyannoupolos utters. For, as Graur, Zheng, et. al. mention, to have 'positive selection' occuring throughout the entire genome, a seeming necessity if "deleterious" mutations are to be weeded out, implies a "mutational load" that is prohibitive. Let's remember it was precisely on this basis that Motoo Kimura proffered his "Neutral Theory." If Stomatoyannoupolos (sto-ma-toy-an-nop-o-los) is correct, then Darwinism makes very little sense. And, of course, EVOLUTION IS A FACT. So, Stomatoyannoupolos must be wrong. I must say that having read bits of Graur, Zheng, et.al's article, the contrast they try to develop between "selective function" and "causal function" seems a bit contrived. It leaves you scratching your head some. Years ago, probably on these pages, I said that whole genome analysis would either prove Darwinism right, or prove it wrong. And Graur, et. al.'s article seems evidence that Darwinism has been proven wrong . . . . . . but not accepted. In sum, Kimura looks at protein polymorphisms and says there's too many for positive selection to explain. So he proposes the Neutral Theory. Now, WGA comes along and finds that the total amount of DNA that is "functional" is way more than 'positive selection' can explain. Stomatoyannoupolos is proposing a new understanding of how the genome works because Darwinian positive selection isn't the answer. When will they ever give up??!!PaV
February 23, 2013
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@ba77 regarding you post about humans and chimps, Les Sherlock expands on that a little more over here: the challenge It is indeed an interesting question, I wonder if we will see another revision of timescales to help account for this intriguing problem.bw
February 23, 2013
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Yes JGuy, Dr. Carter is a powerhouse when it comes to this area. Here are a few clips from a presentation he gave: What Is The Genome? It's Certainly Not Junk! - Dr. Robert Carter - video - (Notes in video description) http://www.metacafe.com/w/8905583 Multidimensional Genome – Dr. Robert Carter – video (Notes in video description) http://www.metacafe.com/w/8905048 Moreover, Dr. Carter's work even extends to the point of falsifying neo_Darwinian' (and theistic evolutionists) claims as to coherently explaining what we find in the human genome: Here is a paper which, though technical, shows that the modern genetic evidence we now have actually supports Adam and Eve. Moreover, the evidence it presents from the latest genetic research is completely inexplicable to neo-Darwinism, i.e. neo-Darwinism, once again, completely falls apart upon rigid scrutiny; (and although I don’t agree with the extreme 6000 year Young Earth model used as a starting presumption in the paper for deriving the graphs, the model, none-the-less, can be amended quite comfortably to a longer time period. Which I, personally, think provides a much more ‘comfortable’ fit to the overall body of evidence) The Non-Mythical Adam and Eve! - Refuting errors by Francis Collins and BioLogos http://creation.com/historical-adam-biologos CMI has a excellent video of the preceding paper by Dr. Carter, that makes the technical aspects of the paper much easier to understand; The Non Mythical Adam and Eve (Dr Robert Carter) - video http://www.youtube.com/watch?v=8ftwf0owpzQ Moreover this genetic evidence for 'Adam and Eve', elucidated by Dr. Carter, is corroborated by other lines of genetic evidence: Human Evolution? - The Compelling Genetic Evidence For Adam and Eve Dr. Fazale Rana - video http://www.metacafe.com/watch/4284482 Dr. Fazale Rana defends the integrity of the genetic evidence for Adam and Eve, on the following site, from some pretty high level criticism: Were They Real? The Scientific Case for Adam and Eve by Fazale Rana - November 2010 http://www.thepoachedegg.net/the-poached-egg/2012/01/were-they-real-the-scientific-case-for-adam-and-eve.htmlbornagain77
February 23, 2013
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A couple excerpts from J.Wells book "The Myth of Junk DNA", quoting Richard Dawkins. Bold emphasis added by me:
SEVERAL RECENT books have likewise used junk DNA as evidence for Darwinism and evidence against design or a creator. In 2004, Richard Dawkins wrote: “Genomes are littered with nonfunctional pseudogenes, faulty duplicates of functional genes that do nothing, while their functional cousins (the word doesn’t even need scare quotes) get on with their business in a different part of the genome. And there’s lots more DNA that doesn’t even deserve the name pseudogene. It too is derived by duplication, but not duplication of functional genes. It consists of multiple copies of junk, ‘tandem repeats’, and other nonsense which may be useful for forensic detectives but which doesn’t seem to be used in the body itself. Once again, creationists might spend some earnest time speculating on why the Creator should bother to litter genomes with untranslated pseudogenes and junk tandem repeat DNA.”23
The following quote is perhaps the most interesting to me. Almost everyone exposed to much of Dawkins speakings, has repeatedly heard him refer to evolution as a fact as any other fact we know. That is quite emphatic!...but as we can see, being an emphatic Dawkins just doesn't make it so:
Richard Dawkins continued to rely on junk DNA in his 2009 book The Greatest Show on Earth: The Evidence for Evolution. “It is a remarkable fact,” Dawkins wrote, “that the greater part (95 per cent in the case of humans) of the genome might as well not be there, for all the difference it makes.” In particular, pseudogenes “are genes that once did something useful but have now been sidelined and are never transcribed or translated.” Dawkins concluded: “What pseudogenes are useful for is embarrassing creationists. It stretches even their creative ingenuity to make up a convincing reason why an intelligent designer should have created a pseudogene… unless he was deliberately setting out to fool us.”30
If he asserted this as a remarkable fact so remarkably wrong....how could anyone trust any emphatic assertion from his mouth. Dawkins now ----> http://www.youtube.com/watch?v=_bjKH43pRB0JGuy
February 22, 2013
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BA77 @ 2 Very good of you to bring up those points from Dr Carter et.al. It seems to be something less talked about, but that actually should be more talked about regarding so called "junk" DNA claim. The problem with Darwinism that first required to call so much of DNA "junk". It shows red handed that Darwinian thinking directly stifled real scientific progress. So, it's interesting now. If Darwinist want to backtrack and call those portions of the DNA that they called "junk" (meaning "garbage") as not "garbage" but more in the sense that it is archived useful stuff (LOL!), then they will pour copious amounts of gasoline on the fire of Haldane's dilemma. Can't win for losing. It must be really uncomfortable as a faithful Darwinist.JGuy
February 22, 2013
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Andy, This is a brilliant article. I learned a lot from reading it. Thank you.vjtorley
February 22, 2013
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Wolfgang Pauli, thou shouldst be living now... Now they've done the maths, they still don't want to know. Ironically, it is they who should be banned from any teaching post relating to empirical science, since they so doggedly hold it back, yet batten, as parasites on the discoveries of genuine scientists; most notably, of course, in the sphere of quantum physics - which their self-applied blinkers would never have allowed them to contemplate in very principle, never mind, research the informed conjectures. It is no coincidence that all the late, great paradigm-changers of the last century were ABSOLUTELY convinced of Intelligent Design, Einstein in particular, seemingly, having nothing but the most profound contempt for the fatuity of his Consensus peers. I use that term, 'peers', of course, very loosely. Ironically, it he, the awe-filled panentheist, that the dunderheads most often accuse of being a pantheist!Axel
February 22, 2013
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Dawkins, 2009: on "junkDNA" "it’s full of junk, which is just as Darwinism predicted… how embarrassing for those creationists who say it shouldn’t be!" Dawkins, 2012: on non-junkDNA… "it’s not full of junk, which is just as Darwinism predicted… nothing for the creationists to take advantage of here, move along!" Richard Dawkins ENCODE 2013 "Junk DNA" http://www.youtube.com/watch?feature=player_detailpage&v=_bjKH43pRB0#t=94sbornagain77
February 22, 2013
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Great entry, Andy, thanks. And thanks also for highlighting this supposedly peer-reviewed article which perfectly illustrates what happens when you try to disguise idealogy with science... and fail, badly. Dan Graur, Yichen Zheng, Nicholas Price, Ricardo B. R. Azevedo, Rebecca A. Zufall and Eran Elhaik have let their emotions and evolutionist faith cloud their judgement about ENCODE's findings... in the name of science too. It's toe-curlingly dreadful. They do neither themselves, nor science any favours with such desperate attempts to put so-called junk DNA back in the garbage again. Just goes to show how important junk DNA is to evolution. Once we discover and indisputably establish function in all DNA (worth more than a million rabbits in the Cambrian!), will the aforementioned scientists agree that neo-darwinism has been falsified? I seriously doubt it.Chris Doyle
February 22, 2013
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Some Darwinists have tried to have it both ways and say that some Darwinists predicted that the majority of DNA would be functional, but,,, Carter: Why Evolutionists Need Junk DNA - December 2009 Excerpt: Junk DNA is not just a label that was tacked on to some DNA that seemed to have no function, but it is something that is required by evolutionary theory. Mathematically, there is too much variation, too much DNA to mutate, and too few generations in which to get it all done. This was the essence of Haldane's work. Without junk DNA, evolutionary theory cannot currently explain how everything works mathematically. Think about it; in the evolutionary model there have only been 3-6 million years since humans and chimps diverged. With average human generation times of 20-30 years, this gives them only 100,000 to 300,000 generations to fix the millions of mutations that separate humans and chimps. This includes at least 35 million single letter differences, over 90 million base pairs of non-shared DNA, nearly 700 extra genes in humans (about 6% not shared with chimpanzees), and tens of thousands of chromosomal rearrangements. Also, the chimp genome is about 13% larger than that of humans, but mostly due to the heterochromatin that caps the chromosome telomeres. All this has to happen in a very short amount of evolutionary time. They don't have enough time, even after discounting the functionality of over 95% of the genome--but their position becomes grave if junk DNA turns out to be functional. Every new function found for junk DNA makes the evolutionists' case that much more difficult. Robert W. Carter - biologist http://indicium.us/2009/12/carter-why-evolutionists-need-junk-dna.html A short history of how junk DNA was mathematically necessitated by Darwinian thought: https://docs.google.com/document/d/14-TXfGxPu-3YeCHtLmxTmL4UZN90Odt135c59yTIFsw/editbornagain77
February 22, 2013
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AJ: Very interesting take. And, you are right to prioritise OOL as the pivot where the whole issue turns on. There is a reason why modern design thought in science began there on the bio side. KFkairosfocus
February 22, 2013
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