We are told, “A study in mice shows for the first time that epigenetics — the molecular mechanisms that determine which genes are turned on or off — plays a key role in determining an individual’s innate drive to exercise:
Why is it that some people love to exercise, and others hate it? Most people would assume it’s all due to genetics, but a new Baylor College of Medicine led study in mice shows for the first time that a different molecular level of regulation — epigenetics — plays a key role in determining one’s innate drive to exercise. Epigenetics refers to molecular mechanisms that determine which genes are turned on or off in different cell types. Since epigenetic mechanisms are inherently more malleable than genetics, the findings suggest a potential way to help ‘program’ people to enjoy being more physically active…
“Our findings suggest that epigenetic mechanisms, such as DNA methylation, that are established in the brain during fetal or early postnatal life, play a major role in determining individual propensity for exercise,” Waterland said. “Nowadays, as decreases in physical activity contribute to the worldwide obesity epidemic, it is increasingly important to understand how all of this works.”
Baylor College of Medicine, “Scientists create ‘epigenetic couch potato’ mouse” at ScienceDaily
Discriminating cats everywhere will love the fat new epigenetic mice.
See also: Epigenetic change: Lamarck, wake up, you’re wanted in the conference room!
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