David Coppedge on cell division as another “hurdle for evolution”

_{Denyse O'Leary

May 8, 2022

Cell biology, Intelligent Design}

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How do cells maintain integrity during division?:

When a stem cell divides, one daughter cell must maintain its stemness (i.e., ability to differentiate into any cell type) while the other specializes. Therein lies another truckload of requirements for coordinated action that, if it goes awry, can spell disaster for an animal or human. Watch this subject grow into a huge problem for evolutionary theory.
Researchers at University of California at Riverside investigated what happens when stem cells divide and specialize. UCR’s reporter Iqbal Pittawala describes how “genome organization influences cell fate.”
“Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical implications for the treatment of human diseases. Central to the cell fate decision process are stem cells residing within each tissue of the body.”
The two daughter cells face a massive organization problem. Even though they contain the same DNA code, they will take on separate roles in the cell. This means that the accessibility of genes between the two cells must radically differ.
Dave Coppedge, “Cell Fate: Another Hurdle for Evolution” at Evolution News and Science Today (May 6, 2022)

Actually, it is only a problem if ruining the careers of those who engage in an honest discussion is no longer an available option.

Comments

OK, great. Evos don't have any clue how much of our genome is junk DNA and they cannot account for the histone octamers that had to arise to organize the genome into something functional.ET_{May 12, 2022
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<Anyone saying the bulk of our or any genome is junk, has to tell us how blind and mindless processes produced the histone octamer spools to organize that junk and functional sequences to maintain viable organisms. Larry Moran can’t do it. He is the worst of the cowards. No one should listen to what he has to say because he ignores the elephant standing on his chest. This is active spooling- dynamic, not static. And without the spools you can’t have a viable organism. Only ignorance says the majority of our genome consists of junk DNA.ET_{May 11, 2022
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Marker:
Evolution has no goal, no direction.
Blind watchmaker evolution has no goal. Genetic algorithms exemplify evolution by means of intelligent design, ie telic processes. They have goals. They are directed.ET_{May 11, 2022
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Fred Hickson:L
ET logic failure.
You are ignorant of logic.
All I’m claiming is mobile genetic elements (which in humans amount to at least half the genome) provide no benefit to the host organism
Your uneducated opinion is meaningless.
All Joe has to do to rebut me is to tell us what did mobile genetic elements ever do for us.
Wrong again. That which can be asserted without evidence can be dismissed without evidence.ET_{May 11, 2022
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FH at 44, The ID explanation is simple: It was all designed. Evolution has no goal, no direction. It's like a driverless car careening down a road, which eventually crashes unless intelligent control can be added.marker_{May 11, 2022
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Martin_r - and never will we see them admit that their confidence (arrogance) was originally misplaced in spite of all the rethinking, surprises, shaking up, contradictions, conflicts, challenges and upendings they report. No, they report the "new insights" with as much hubris as they did the refuted ones. As if nobody was paying attention to their previous claims -- and maybe nobody was. If you keep talking in circles enough, nobody bothers listening any more. What difference does it make if giraffes evolved by stretching their neck for leaves at the top of trees or by a mating-ritual? "They evolved" is the only important "fact" that all supposedly-educated people need to believe in. At the same time, to maintain authority over the "scientifically illiterate", in spite of contradicting themselves, they just need a credentialing organization, with vested interest in self-selecting for Darwinian apostles, to stamp their teachers with "evolution expert" label and people won't question whatever nonsense they come up with.Silver Asiatic_{May 11, 2022
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Hickson
Joe has to do to rebut me is to tell us what did mobile genetic elements ever do for us.
Your self-confidence amazes me ... I have asked this question before, but when i see someone like you, i have to ask again: What makes Darwinists so trustworthy ? Today, every other Darwinian biology paper starts like this: "...current concepts are reviewed..." "...uprooting current thinking...." "... latest findings contradict the current dogma...." “… it challenges a long-held theory …” "... in contrast to the decades-long dogma ..." “… it upends a common view…” “… it needs a rethink … ” “… the findings are surprising and unexpected …. ” “… it shakes up the dogma … ” “… earlier than thought…” “… younger than thought….” “… smarter than thought ….” “… more complex than thought ….” So what makes Darwinists so trustworthy ? They seem to be always wrong ...martin_r_{May 11, 2022
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ET logic failure. All I'm claiming is mobile genetic elements (which in humans amount to at least half the genome) provide no benefit to the host organism and thus deserve the title "Junk". All Joe has to do to rebut me is to tell us what did mobile genetic elements ever do for us. (Apart from the aqueduct, obviously - or should I say obvioulsy.)Fred Hickson_{May 11, 2022
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Fred Hickson:
Mobile genetic elements? Transposons? Retrotransposons?
Transposons carry within their sequence the coding for two of the proteins required for it to move around. Please demonstrate how blind and mindless processes produced such a thing. Or admit that you are clueless.ET_{May 11, 2022
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What's the ID explanation?Fred Hickson_{May 10, 2022
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Only ignorance says the majority of our genome consists of junk DNA.
Mobile genetic elements? Transposons? Retrotransposons?Fred Hickson_{May 10, 2022
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JVL:
“spools to organise that junk” . . . really? What does that mean? Are you saying the junk is organised? Are you saying the ‘junk’ and the functional sequences are organised so the system recognises what is ‘junk’ and what is functional?
Wow. Histone octamers. Look them up. And yes, without them the DNA would be a mess. Seriously, how ignorant are you of cellular biology? Anyone saying the bulk of our or any genome is junk, has to tell us how blind and mindless processes produced the histone octamer spools to organize that junk and functional sequences to maintain viable organisms. Larry Moran can’t do it. He is the worst of the cowards. No one should listen to what he has to say because he ignores the elephant standing on his chest. This is active spooling- dynamic, not static. And without the spools you can't have a viable organism. Only ignorance says the majority of our genome consists of junk DNA.ET_{May 10, 2022
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Carry on, Marker, carry on. You could change the World.Fred Hickson_{May 10, 2022
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live and what? Are answers useful here or not? I'll continue to post information. Finger pointing is useless.marker_{May 10, 2022
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Well, live and let live, marker.Fred Hickson_{May 10, 2022
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blogosphere? Seriously? The Global Cabal of Word Inventors and Repackagers has no hold over me. I have a long list of fake/invented words I will never use. Meanwhile, progress begins with facts. As opposed to fencing off portions of reality.marker_{May 10, 2022
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JVL I will do if you agree to try and explain the wide disparity in genome sizes from a design point of view.
:) This is another point that destroy darwinism :"gradual" acumulation of new mutations/information ", except information require an intelligence source. Answer is very simple: a mind can code softwares with different levels of complexity and on different levels of hardwares(A MIND HAS FLEXIBILITY) , while physical laws being unidimensional can do exactly what Origin of Life experts have been doing for 100 years now: nothing.Lieutenant Commander Data_{May 10, 2022
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Hey, does Fred Hickson get a say here? I mean it's no big deal. This little corner of the blogosphere can raise fences against reality. Carry onFred Hickson_{May 10, 2022
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Marker
An us versus them discussion has no value. I recommend sticking with facts.
Indeed! A discussion can't happen if facts are in dispute. Wouldn't it be great if we all started from some common ground and progressed from there? I am an incurable optimist.Fred Hickson_{May 10, 2022
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Marker
An us versus them discussion has no value. I recommend sticking with facts.
Indeed! A discussion can't happen if facts are in dispute. Wouldn't it be great if we all started from some cook ground and progressed from there? I am an incurable optimist.Fred Hickson_{May 10, 2022
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Martin_r: read carefully mine and Hickson’s posts … perhaps you will understand why i posted the ScienceDaily article … I will do if you agree to try and explain the wide disparity in genome sizes from a design point of view. Deal?JVL_{May 10, 2022
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I am unconcerned with emotion-based responses. The rants can go on for years but facts remain facts.marker_{May 10, 2022
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JVL @29 read carefully mine and Hickson's posts ... perhaps you will understand why i posted the ScienceDaily article ...martin_r_{May 10, 2022
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I recommend sticking with facts.
Rare on UD. Discussions usually based on emotions. Add logic though because that is what ID is all about. Facts + logic. ID is Science+ The "+" is logic.jerry_{May 10, 2022
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Martin_r: new research shows that one piece of junk DNA — the promoter of a virus-based transposon — plays a critical role in cell proliferation and timing of embryo implantation in mice. Oooo, one piece. ONE PIECE! And you think that destroys the whole idea that a large portion of the human genome is junk? Let's consider some other living creatures and their genomes . . . The human genome is about 3 GB of base pairs. About since there is a difference between different individuals between repeated sequences. So did you know that the Polychaos dubium has a genome that is 670 GB? Or the Paris japonica which has a genome which is 150 GB? What about the Tetraodon nigroviridis which has a genome which is 390 MB? https://en.wikipedia.org/wiki/Genome#Genome_size If you have design explanations for these disparities then I'd love to hear them. You may have a good explanation but I am not going to pre-suppose your response.JVL_{May 10, 2022
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An us versus them discussion has no value. I recommend sticking with facts.marker_{May 10, 2022
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The Origin of the Term “Junk DNA”: A Historical Whodunnit Who else than darwinists?Lieutenant Commander Data_{May 10, 2022
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LCD, thanks for that GENE RELOCATION article, very interesting ... However, i doesn't answer my question, how the cell knows what is the location of a particular gene ... i understand, there are some bookmarks, but it still doesn't explain how the cell knows which bookmark stands for a particular gene ... so some 'map of bookmarks' is required in any case... if i am wrong, please correct me ... PS: by the way, i have no doubts that the cell is very smart (or the one who created it)martin_r_{May 10, 2022
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ET: Anyone saying the bulk of our or any genome is junk, has to tell us how blind and mindless processes produced spools to organize that junk and functional sequences to maintain viable organisms. "spools to organise that junk" . . . really? What does that mean? Are you saying the junk is organised? Are you saying the 'junk' and the functional sequences are organised so the system recognises what is 'junk' and what is functional? Perhaps you should keep up on the literature. Those kind of things are clearly and obviously addressed. If you're interested in finding out that is.JVL_{May 10, 2022
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It appears that part of the goal here is to just confuse the issue. I did not invent the term "junk DNA." I did not write articles about it. But here, as opposed to say a journal like Nature, the recommendation is to discard it? Why? Inconvenient? Gets in the way of a belief system? If anyone wants to discard the term, explain why.marker_{May 10, 2022
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