Many RNA-binding proteins have modular structures and are composed of multiple repeats of just a few basic domains that are arranged in various ways to satisfy their diverse functional requirements. Recent studies have investigated how different modules cooperate in regulating the RNA-binding specificity and the biological activity of these proteins. They have also investigated how multiple modules cooperate with enzymatic domains to regulate the catalytic activity of enzymes that act on RNA. These studies have shown how, for many RNA-binding proteins, multiple modules define the fundamental structural unit that is responsible for biological function.
Bradley M. Lunde, Claire Moore & Gabriele VaraniÃ‚Â
Nature Reviews Molecular Cell Biology 8, 479-490 (June 2007) | doi:10.1038/nrm2178
This paper is yet another of the many examples of howÃ‚Â intelligently designed biological systems appear to be. We are continually told to keep in mind that they are only apparently designed. When will it become acceptable to attribute realÃ‚Â design where it is clearly seen?