The remarkable process of cell division

_{Denyse O'Leary

February 2, 2022

Cell biology, Intelligent Design}

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Chromosomes are densely packed DNA. The two “sister chromatids” of a chromosome, having been accurately duplicated during prophase and secured by centromeres, are arranged with all the other chromosomes on the spindle axis in metaphase. Soon after they are winched apart in anaphase into daughter cells. This elaborate choreography takes place every time a cell divides. The cell cycle is fascinating to anyone who has witnessed it under a light microscope, as you can see here:
Evolution News, “DNA Packing: One of the Supreme Wonders of Nature” at Evolution News and Science Today (January 31, 2022)

Remarkable movies made with super-resolution atomic force microscopy show the parts of cohesin undergoing conformational changes. These hand-over-hand motions operate in the dark without eyes, using ATP for energy. They get it right every time!
Evolution News, “DNA Packing: One of the Supreme Wonders of Nature” at Evolution News and Science Today (January 31, 2022)

The paper is open access.

You may also wish to read: Everything is coming up non-random (PAV)

Comments

JVL,
Upon what do you base your ‘sense’? That I don’t support theological support for widely held moral values? Do you see largely secular societies in Europe encompassing hideously dangerous policies and laws? Things that have been demonstrated to destabilise their countries? What actual evidence do you have for your slippery slope ‘sense’?
My use of the word "sense" was in regard to relative degrees of apparent vigilance. I base the perception on two things: 1) a post of yours from a month or so ago, where you admonished BA77 to go out and watch a movie or something instead of harping on issues here at UD, and 2) the fact that you don't mention a single problem that Europe might have; only social conditions that are at the moment going the way you like. To have no concerns at all is unusual from my perspective. Is nothing required to maintain the European utopia? No dangers from any angles at all? The "eternal vigilance" problem has been solved?EDTA_{February 4, 2022
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JVL, regardless of whomever your theological rant was directed towards, you still have not even started to explain how it is even remotely possible for mindless Darwinian processes to produce such an astonishing thing as 'DNA packing'.
How DNA is Packaged (Advanced) https://www.youtube.com/watch?v=gbSIBhFwQ4s
Frankly, to suggest that such astonishing complexity can be had by mindless Darwinian processes is, by all rights, to be considered insane. To give you a small clue just how insane this 'mindless' claim is from Darwinian atheists, I will give you the following snippet,
Genes and Organisms: Improvising the Dance of Life - Stephen L. Talbott - Nov. 10, 2015 Excerpt: The performances of countless cells in your body are redirected and coordinated as part of a global narrative for which no localized controller exists. This redirection and coordination includes a unique choreography of gene expression in each individual cell. Hundreds or thousands of DNA sequences move (or are moved) within vast numbers of cell nuclei, and are subjected to extraordinarily nuanced, locally modulated chemical activity so as to contribute appropriately to bodily requirements that are nowhere codified — least of all in those DNA sequences.,,, DNA in its larger matrix You may recall from my earlier article, “Getting Over the Code Delusion” (Talbott 2010), that packing DNA into a typical cell nucleus is like packing about 24 miles of very thin, double-stranded string into a tennis ball, with the string cut up (in the normal human case) into 46 pieces, corresponding to our 46 chromosomes. To locate a protein-coding gene of typical size within all that DNA is like homing in on a one-half-inch stretch within those 24 miles. Or, rather, two relevant half-inch stretches located on different pieces of string, since we typically have two copies of any given gene. Except that sometimes one copy differs from the other and one version is not supposed to be expressed, or one version needs to be expressed more than the other, or the product of one needs to be modified relative to the other. So part of the job may be to distinguish one of those half-inch stretches from the other. “Decisions” everywhere, it seems. But no such decisions are made in a vacuum. As it happens, the chromosome does not consist of a naked DNA double helix. Our DNA, rather, is bound up with a massive, intricate, and dynamic protein-RNA-small molecule complex (called chromatin) that is as fully “informative” for the cell as the DNA sequence itself — and, you might say, much more active and directive.,,, the cell, by managing the shifting patterns of the chromatin infrastructure within which DNA is embedded, brings our chromosomes into movement on widely varying scales. These include large looping movements that put particular genes into connection with essential regulatory sequences and with other, related genes (that is, with other one-half inch stretches of our “24 miles of string in a tennis ball”).,,, A gene is not in any case the kind of rigidly defined entity one might hope to calculate with. As a functional unit appropriate to current circumstances, it must be cobbled together by the cell according to the needs of the moment. There is no neatly predefined path to follow once the cell has located the “right” half inch or so of string, or once it has done whatever is necessary to bring that locus into proper relation with other chromosomal loci participating in the same “dance”. One issue has to do with the fact that there are two strands in the DNA double helix and, starting from any particular point, it is possible to transcibe either of two DNA sequences in either of two directions: “forward” along one strand, or “backward” along the other. This yields two completely different products. One of them is very likely not even a protein-coding RNA, and yet it may still play a vital role in gene expression and in cellular processes more generally. And even when the cell would proceed in one particular direction, it must “choose” the exact point in the genetic sequence at which to begin. Different starting points can yield functionally distinct results. “Many studies focusing on single genes have shown that the choice of a specific transcription start site has critical roles during development and cell differentiation, and aberrations in . . . transcription start site use lead to various diseases including cancer, neuropsychiatric disorders, and developmental disorders”.8,,, http://www.natureinstitute.org/txt/st/org/comm/ar/2015/genes_29.htm
JVL, in case you were wondering, now would be a good time for you to thank God for being 'fearfully and wonderfully made':
Psalm 139:13-14 For You formed my inmost being; You knit me together in my mother’s womb. I praise You, for I am fearfully and wonderfully made. Marvelous are Your works, and I know this very well.
bornagain77_{February 4, 2022
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EDTA: I’m glad for that too. But the price of liberty (and lots of other good things) is indeed eternal vigilance. I don’t sense the same degree of vigilance from you as I do from BA77 and KF for instance. And we have genuine concerns that, with a flimsy foundation for morals, anything could become permissible with little notice. Upon what do you base your 'sense'? That I don't support theological support for widely held moral values? Do you see largely secular societies in Europe encompassing hideously dangerous policies and laws? Things that have been demonstrated to destabilise their countries? What actual evidence do you have for your slippery slope 'sense'?JVL_{February 4, 2022
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Bornagain77: JVL, and your anti-theology rant qualifies in explaining exactly how ‘astonishing’ DNA packing arose by mindless Darwinian processes how exactly? I think, if you actually paid attention, you'll find I was criticising your view and the way you express it and not Christianity itself. You do realize that your personal ‘distaste’ of “God explanations” does not remotely qualify as an actual scientific rebuttal of “God explanations” do you not? Or are you actually that blind to your own personal biases against God? Are you that oblivious to the fact that it's not possible to test the God hypothesis in a lab? Can it be considered science then?JVL_{February 4, 2022
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Chuck. thank you for the "THERE IS" explanation :)))) you must be kidding ... I know, everybody knows... THERE ARE lots of thing inside a cell... did Darwinists show you how it came to existence ? So, one again, what exactly Is taught about cell division in schools?martin_r_{February 3, 2022
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JVL, "...in my father’s lifetime Germans and Italians were killing French and English and Danish, and Belgians and Poles and Dutch and Finns but now they are all working together..." I'm glad for that too. But the price of liberty (and lots of other good things) is indeed eternal vigilance. I don't sense the same degree of vigilance from you as I do from BA77 and KF for instance. And we have genuine concerns that, with a flimsy foundation for morals, anything could become permissible with little notice.EDTA_{February 3, 2022
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Martin_r @ 7 Typically there is a unit on the cell that includes the basics of mitosis and meiosischuckdarwin_{February 3, 2022
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Chuck and Co.
This Is simply basic cell biology. Taught in any advanced high school or college freshman biology class.
what exactly about cell division is taught in advanced high school/college freshman biology class ? as far as i know, it is taught that THERE IS a cell division ... is it also taught how cell division evolved? anything scientific ? Not just-so stories and Darwinian fairy tales ....martin_r_{February 3, 2022
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JVL, and your anti-theology rant qualifies in explaining exactly how 'astonishing' DNA packing arose by mindless Darwinian processes how exactly?
Episode 8/13: Nucleotides // A Course on Abiogenesis by Dr. James Tour https://www.youtube.com/watch?v=CYiguQYCSio How DNA is Packaged (Advanced) https://www.youtube.com/watch?v=gbSIBhFwQ4s
You do realize that your personal 'distaste' of "God explanations" does not remotely qualify as an actual scientific rebuttal of "God explanations" do you not? Or are you actually that blind to your own personal biases against God?
2 Corinthians 4:4 whose minds the god of this age has blinded, who do not believe, lest the light of the gospel of the glory of Christ, who is the image of God, should shine on them.
bornagain77_{February 3, 2022
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CD, does not make it any less of a wonder. Your observationally anchored account of its origin by blind chance and mechanical necessity , is? _____ KFkairosfocus_{February 3, 2022
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This Is simply basic cell biology. Taught in any advanced high school or college freshman biology class.chuckdarwin_{February 3, 2022
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Bornagain77: JVL, Seversky, ChucyD, etc.., Crickets got your tongue? You don't have to wait for one of us to respond to post several of your extensive copy-and-pasted, mined references replies. Why don't you tell us AGAIN about how amazing and incredible the living world is, how ludicrous and stupid it is to conceive of it being undesigned, don't forget a vaguely pertinent Bible quote at the end. Oh and please throw in several reasons why modern science could not have arisen without not just any religious view but Christianity. You may also indulge in the designer-centric view that the universe was created to be discoverable. Or, you could just realise that you've been saying the same things over and over and over again for years and that's the reason that no one actually reads your posts anymore. I must admit, I am a bit curious about your contention that you feel you are in some kind of conflict (between the forces of good and evil? God and the god-less?) so, therefore, you have to be vigilant and attack the heathens whenever they say anything you disagree with. I don't really know what you are afraid of: many European countries are generally non-religious in word and deed and they are doing just fine. For example: the rate of gun crime in America is much higher than it is in any European country. There are no homosexual vs homophobic pitched battles in Europe. We don't have doctors being killed by abortion protestors. Our elections are well run and uncontested to any significant effect. We take in our share of economic and cultural refugees which does cost but it is the right thing to do isn't it? We mostly have what you would call socialistic health care systems which are roundly supported and appreciated by the populace; who wouldn't be in support of a system which promises decent health care even to those who have no job or paid for coverage? We even offer coverage to guests and recent arrivals. Again, the right thing to do surely. Our education systems are good and respected. We have active and strong cultural support and output. Yet the fact that we sanction same-sex marriage and humanitarian values means you assume we're all poised on the edge of some kind of ideological precipice. Here's a thought: in my father's lifetime Germans and Italians were killing French and English and Danish, and Belgians and Poles and Dutch and Finns but now they are all working together, economically and strategically. After millennia of conflict Europe is relatively peaceful and co-operative. That's a good thing isn't it?JVL_{February 3, 2022
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how on earth can cell division be ever explained by Darwinism ??? all scientists got mad ?martin_r_{February 3, 2022
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JVL, Seversky, ChucyD, etc.., Crickets got your tongue? :)
https://c.tenor.com/Y0fH-3sQDQsAAAAC/jake-tapper-jake-tapper-crickets.gif
bornagain77_{February 3, 2022
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