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This summer’s theory, chlorine-based life, struts the catwalk

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Thumbnail for version as of 00:06, 31 May 2011
chlorine gas/W. Oelen

From Carl Zimmer at Discover Magazine’s “The Loom” blog, we learn, “Last year arsenic-based life, now chlorine-based life” (12011/07/06)

I checked in with Steven Benner, a chemist who has raised a lot of concerns about the arsenic-life research last year. What did he think of the new research?“It looks true,” he said.

Benner also pointed out that using chlorine in DNA is a pretty modest changed compared to what would have been required to substitute arsenic for phosphorus in the backbone of DNA. Swapping in chlorine doesn’t change how the compound reacts with other compounds, doesn’t
change its size much, doesn’t change its stability much, and so on.

On the other hand, it appears to have the advantage of being real.

That’s something, to be sure. Currently, fanzines are arguing as to whether it should be called”chlorine-based” life, anyway. Informative comment thread shows chlorine phenomenon well-known and used for practical purposes in the past.

File under: High hopes, alongside Arsenic-driven origin of life takes hit” and “This guy knows exactly what happened in the history of life on Earth”

Hat tip: Pos-Darwinista

Comments
Yes, some people complained about the post's title at the site, too. - UD NewsNews
July 8, 2011
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It is not chlorine-based life. It is carbon-based life (E. coli), evolved to tolerate using chlorouracil instead of thymine. The paper is here: http://onlinelibrary.wiley.com/doi/10.1002/anie.201100535/abstract "The element chlorine does not occur in the chemical composition of wild-type E. coli, yet has become essential for the proliferation of its descendants CLU2, CLU4, and CLU5. ... In summary, we set out to evolve genomic DNA composed of the three canonical bases adenine, cytosine, and guanine and the artificial base 5-chlorouracil in an Escherichia coli strain lacking thymidylate synthase and requiring thymine. Selection over 25 weeks in a cultivation device that automatically adjusts the lowest tolerable thymine concentration yielded descendants that grew with only chlorouracil. "DrREC
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