… they are here already. Here (Along with grammar in genes.):
The genes that RNA Polymerase II reads before the midblastula transition were often preceded by a promoter that seemed to yell, “Urgent! Don’t even think about pausing.” These promoters contain what’s known as a TATA-box, named for its conserved arrangement of nucleotides, most commonly TATAA.
As cell division slows down during the midblastula transition, cells have the luxury of pausing, perhaps to fine-tune when transcription begins, Zeitlinger says.
These midblastula genes were regulated by promoters that contain a variety of specific promoter elements associated with paused RNA polymerase, including GAGA, Downstream Promoter Element (DPE), Motif Two Element (MTF) and Pause Button (PB).
The team also found a third type of promoter, which contained both the TATA-box and the pausing sequences. At these genes, RNA polymerase II does not pause initially but begins to pause during the midblastula transition.
Zeitlinger hopes learning more about promoters will give clues to the functions of unknown genes.
As someone said about something similar a while back,
“Biologists must constantly keep in mind that what they see was not designed, but rather evolved.”
“Biologists must constantly keep in mind that what they see was not designed, but rather evolved.”
“Biologists must constantly keep in mind…”
Riffing off this guy.
See, the Darwin lobby’s problem isn’t the design theorists. Their problem is that in order to proclaim that it all unfolds with no design, meaning, or purpose, they must persuade us all to think that way about language itself.
Many people who get on fine with Jesus n’ Darwin n’ Oprah are justifiably skeptial when Darwin’s fans push it that far.