From neuroscientist Simon Gandevia at The Conversation:
Spectacular failures to replicate key scientific findings have been documented of late, particularly in biology, psychology and medicine.
A report on the issue, published in Nature this May, found that about 90% of some 1,576 researchers surveyed now believe there is a reproducibility crisis in science.
One contributing factor is easily identified. It is the high rate of so-called false discoveries in the literature. They are false-positive findings and lead to the erroneous perception that a definitive scientific discovery has been made.
This high rate occurs because the studies that are published often have low statistical power to identify a genuine discovery when it is there, and the effects being sought are often small. More.
See also: Peer review unscientific: Tough words from Nature
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