Uncommon Descent Serving The Intelligent Design Community
Author

Cornelius Hunter

Chaperonins: Open and Shut Case

A protein is created in the cell by copying its DNA gene, making any necessary edits to the copy, and passing the copy to the ribosome machine which uses the genetic code to translate the copy (a series of nucleotides) into the protein structure (a series of amino acids). But the story does not end here. The final step, after translation, is to fold the protein into its three dimensional structure. It is a step that is difficult to monitor and difficult to predict. The chain of amino acids folds up in a tiny fraction of a second and the final shape it assumes is not obvious. And sometimes the folding process is literally hidden as the nascent protein chain Read More ›

The Evolution of Serendipity

A key question for evolution has always been: How does biological variation arise? Darwin’s theory of evolution explained that natural selection killed off the less-fit variations, but how did the variation arise in the first place? In the nineteenth century the mechanisms of biological variation were not well understood and it was possible to imagine a sort of simple, perturbing force at work which gradually altered designs. This model did not match up very well with what Gregor Mendel was discovering about change in pea plants. About the same time that Darwin was working on revisions to his book Mendel was uncovering the fundamental laws of genetics. But Mendelian genetics would call for discrete jumps in biological variation rather than Read More ›

Prestin and Darwin’s Gardener

A fundamental, and often false, prediction of evolution is that functionally unconstrained DNA should not be conserved in distant species. As described here, everything from proteins to long stretches of DNA, though highly similar across different species, defy evolutionsts who search for a functional constraint, as required by their theory. And how do evolutionists respond? They claim that the mystery DNA must have a function, even though myriad tests have found none. If we cannot detect the function, then there must be a problem with the tests. There must be a function which otherwise is undetectable to us. It is a perfect example of how religious belief resists falsification as Antony Flew once illustrated in his gardener parable.  Read more

Proteins That Regulate Protein Production

Most people understand that our genes are stored in our DNA but what is less commonly understood is how the cell determines which genes to use at any one time. The DNA in our cells contain tens of thousands of protein-coding genes whose proteins serve a great variety of purposes. They serve as railroad tracks, precision tunnels, enzymes to speed up reactions and environmental sensors to name just a few. And some proteins go back to the DNA and bind to the double helix, as part of a complex regulatory network that determines which genes to use to make new proteins. In other words, the cell determines which genes, to use to make new proteins, by using existing proteins. But Read More ›

New Intron Research Reveals Same Old Contradictions

In eukaryotes the DNA genes are sometimes interrupted by non coding segments. These intragenic regions, or introns, are cut out of the transcribed DNA before the copy is sent to the ribosome for translation into a protein. Naturally evolutionists have always believed introns are a result of evolution, but their explanations are strained. As one recent paper explained, understanding why such introns exist and their evolutionary origins is “a problem that has proved a conundrum for the past 30 years.”  Read more

Ribosome Checks for Translation Errors

There is a vast network of information flow in a typical cell, and along with that flow there is a vast network of error checking. Damage to DNA sequences is remedied, the transcribing of DNA is checked and corrected, and at the ribosome the translation process is checked and controlled. In fact, recent research has found that the ribosome not only carefully sets up the codon-to-amino-acid translation process for success, but if an error is made the ribosome detects it and takes action after the translation process.  Read more

A New Plant Defense: Switch the Flowering Time

A new amazing strategy has been discovered to add to the list of defenses plants use against herbivores. It has long been known, for instance, that plants detect the secretions from caterpillars and respond with toxins and chemicals that slow the caterpillars’ digestion. Now a new defensive strategy has been discovered: the altering of the flowering time. This has been observed in a tobacco plant which produces new morning-opening flowers when attacked by larvae of the hawkmoth pollinator.  Read more

Evolution’s Kobayashi Maru Scenario

By mandating methodological naturalism evolutionists place themselves into a no-win scenario. Like Star Trek’s Captain Kirk who reprogrammed the computer in order to defeat the Kobayashi Maru scenario training exercise, evolutionists can only cheat their way out of their methodological naturalism mandate. If they give a straight answer they undermine their own claims about evolution. The problem here is not methodological naturalism itself, which is a perfectly reasonable way to do science. The problem is that, in the hands of evolutionists, it becomes dogma rather than guidance. And the problem is not merely a philosophical fine point–in mandating methodological naturalism evolutionists reveal the absurdity of their ideas and simultaneously do substantial harm to science.  Read more

A Question for Joe Felsenstein (and Everyone Else)

Joe Felsenstein, and most other evolutionists, tell us that science must be restricted to law-like causes and explanations. In a word, they require the scientific method to be restricted to naturalism. While this methodological naturalism seems like a reasonable way to do science, it is an incomplete instruction. There remains the question of what to do when methodological naturalism doesn’t work.  Read more

The Problem(s) With Penguins

Penguins have always been a problem for evolution. Their flippers, for instance, are supposed to be the vestiges of wings. “Say again …?” you say? That’s right, according to evolution penguins are supposed to have evolved from an earlier bird with wings. The bird morphed into a penguin and the wings morphed into the penguin’s flippers. Anyone who has seen a penguin swim knows its flippers are not just a happenstance design. The penguin is an incredible swimmer and the last thing that comes to mind is that its flippers somehow evolved from a wing. Of course for evolutionists this transition is a fact, even though they don’t know how it happened. Now penguins have been discovered to defy the Read More ›

A De Novo Gene: Unlikely and Very Unlikely

If you scramble about 90% of a protein sequence—randomly replacing amino acids with different ones—would the protein still work? That is what evolutionists are implying in order to make sense of their theory. The problem is that evolution’s explanations for de novo genes are unlikely and very unlikely. In the case of the T-urf13 de novo gene, the two choices seem to be (i) a one in ten million shot that protein coding sequences just happened to be lying around waiting for use or (ii) only about 10% of the T-urf13 sequence really matters and you can scramble the rest with no effect.  Read more

Global Warming Quandary Resolved

New research out this week has resolved a long-standing, and important, quandary about the causes of global warming. While several models point to anthropogenic CO2 and other greenhouse gases as the leading cause of global warming, the warming trends do not quite match the history of anthropogenic CO2. In fact, shrinking glaciers and other undeniable evidences of warming trace back to about the mid seventeenth century. But this predates the significant rise in anthropogenic CO2 that came later in later centuries. Now environmental researchers have solved the puzzle. While CO2 is undoubtedly an important factor in certain warming events, by far the most significant cause is the hot air emitted by evolutionists. In other words, anthropogenic theory rather than anthropogenic Read More ›

A Non Genetic Protein Translation Mechanism Adds More Complexity to Cellular Adaptation

Biology’s sophisticated adaptation machine has now been discovered to be even more sophisticated. In recent years the types of adaptation often claimed to be examples of evolution in action have been found to be driven by complex mechanisms that respond to environmental pressures. It was yet another falsification of evolutionary expectations. Organisms responded far more quickly than neo Darwinism predicted, and this was because the responses were not the result of evolution’s blind variation, but rather of directed mechanisms. Gene regulation and even gene modification mechanisms have been discovered which not only implement helpful adaptations, but they implement adaptations that are heritable.  Read more

De Novo Genes and Normal Science

Science can be wrong about some things and still make great discoveries and inventions. One can believe the earth is flat or that electrons are nothing more than tiny billiard balls and still make progress. The history of science is a fascinating story of erroneous theories and beliefs intertwined with remarkable progress. And even today’s life science research journals are full of asinine statements, arising from a belief in evolution, mingled with perfectly good scientific research. Most scientists can distinguish between the hard data gathered in the laboratory and the obligatory evolutionary framework into which the data are forced and presented. You focus on the former in order to make progress and tolerate the latter in order to get funded. Read More ›

De Novo Genes: The Evolutionary Explanation

Cells have remarkable adaptation capabilities. They can precisely adjust which segments of the genome are copied for use in the cell. They can edit and regulate those DNA copies according to their needs. And they can even modify the DNA itself, such as with adaptive mutations, to accommodate environmental pressures. And in addition to these examples, cells can create completely new, de novo, genes in an evolutionary instant. It is yet another biological capability that reveals the scientific weakness of evolutionary theory.  Read more