Video animation of RNA interference (RNAi)
The researchers discovered the caging behaviour with Shigella, a bacterium that causes sometimes lethal diarrhoea in humans and other primates.
Whether in an RNA World, Peptide World, Lipid World, or other composomal Metabolism-First model
“The protective mechanism is controlled by the starvation-signaling stringent response (SR),”
If the mole rat lived in underground isolation for so long, how did it develop such disease resistance? With humans, for example, isolation from a disease is precisely what makes it deadly.
“Interferon is secreted and picked up by surrounding cells, causing them to turn on hundreds of genes that act to combat the infection.”