'Junk DNA' Intelligent Design

Another job for “junk DNA”: Killing cancer in blind mole rats

Researcher: “The paper describes an important new mechanistic insight into the way one can trigger inflammatory signals in cancer cells to either kill them directly or make them vulnerable to cancer-killing therapies,” says cancer biologist Stephen Baylin of Johns Hopkins School of Medicine, who was not involved in the research. “The importance of it is really quite profound.”

Epigenetics Intelligent Design

Epigenetics: Biologists discover 71 new “imprinted” genes in the mouse genome

Researchers: Scientists have yet to work out how one parental version of a given gene can be switched (or faded) on or off and maintained that way while the other is in the opposite state. It is known that much of the on/off switching occurs during the formation of gametes (sperm and egg), but the precise mechanisms remain unclear. This new study points to the intriguing possibility that some imprinted genes may not be marked in gametes, but become active later in development, or even in adulthood.

Cell biology Intelligent Design

How, exactly, do damaged or diseased cells “commit suicide” to protect the body?

Why this matters: Cancer cells avoid destruction by inhibiting a process (which is called necroptosis). And necroptosis happening when it shouldn’t “is linked to the damage from multiple sclerosis, Parkinson’s disease and tissue injury from blood flow loss.” Targeting these processes could be an avenue for treatment.

Cell biology Design inference Intelligent Design

Researchers: A kill cancer code is embedded in every cell

From ScienceDaily: A kill code is embedded in every cell in the body whose function may be to cause the self-destruction of cells that become cancerous, reports a new Northwestern Medicine study. As soon as the cell’s inner bodyguards sense it is mutating into cancer, they punch in the kill code to extinguish the mutating Read More…