VIDEO: Doug Axe on making odds on getting to a protein by chance in Amino Acid sequence space
In Illustra Media’s Darwin’s Dilemma, there is a clip on proteins as islands of function in amino acid sequence space: [youtube h38Xi-Jz9yk] Food for thought. As a stimulus to such, let us next note how the bloggist Wintery Knight has given an interesting summary of the challenges involved if a chance-dominated process is invoked for a hypothetical 100-AA polypeptide: Let’s calculate the odds of building a protein composed of a functional chain of 100 amino acids, by chance. (Think of a meaningful English sentence built with 100 scrabble letters, held together with glue) Sub-problems: BONDING: You need 99 peptide bonds between the 100 amino acids. The odds of getting a peptide bond is 50%. The probability of building a chain Read More ›