P-values: Has science got probability wrong?
From professor of pharmacology David Colquhoun at Aeon: The aim of science is to establish facts, as accurately as possible. It is therefore crucially important to determine whether an observed phenomenon is real, or whether it’s the result of pure chance. If you declare that you’ve discovered something when in fact it’s just random, that’s called a false discovery or a false positive. And false positives are alarmingly common in some areas of medical science. … In 2005, the epidemiologist John Ioannidis at Stanford caused a storm when he wrote the paper ‘Why Most Published Research Findings Are False’, focusing on results in certain areas of biomedicine. He’s been vindicated by subsequent investigations. For example, a recent article found that Read More ›