I finished reading Provine’s last book a few weeks ago, and have meant to post something about it ever since.
In his book, The ‘Random Genetic Drift’ Fallacy, Provine hammers his main thesis over and over: that is, that genetic changes in small populations occur not because of “random genetic drift,” but because of “inbreeding.”
The entire book is meant to show that the entirety of population genetics is based on a basic misunderstanding by Sewell Wright of what was happening in populations, a misunderstanding that allowed R.A. Fisher’s analysis to prevail, a model of alleles mutating around a specific gene location, or locus, which, IIRC, he called F.
Provine says over and over again that descendants don’t inherit this locus F and its mutants, but actual chromosomes.
Because of a lack of clarity in his central claim, I would advise anyone reading the book to read Chapter Six after Chapter One, and then to go back and read the intervening chapters, and then the final chapter.
I was planing out laying out Provine’s fundamental assertions, and the implications that go with it, but while looking around for some reviews of Provine’s work I found one that was so keen, and that captured all the elements of the book—a review by a population geneticist who knew Provine—that I’ll just include a link.
Here it is. You can see that Provine thinks that the fundamental assertion of the Modern Synthesis, made by Fisher, misses the mark.