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Genetic Literacy Project: Most epigenetic changes not passed on to offspring

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That’s a good thing but never a sure one:

While most epigenetic information is erased and reprogrammed before it can be passed on to offspring, some epigenetic information may escape erasure and may thus be passed on to an individual’s children (and potentially to subsequent generations). In mammals, there are at least two main periods of demethylation and remethylation — once during the development of germ cells (the precursor cells that will become sperm and eggs), and once in the earliest stages of an embryo’s development. During demethylation, ancestral methylation patterns (key epigenetic marks) are almost completely erased. The regions that are not demethylated may represent “hot spots of transgenerational epigenetic inheritance,” according to a 2019 research review on epigenetic regulation by Wang et al. It’s important to note that there has not yet been clear evidence in humans of transgenerational epigenetic inheritance, and that the topic of how transgenerational epigenetic inheritance might work in humans is highly debated.

Kristen Hovet, “4 things to know about epigenetics, including that most changes are not passed on to offspring” at Genetic Literacy Project

Well, epigenetics is harder to study in humans because human development takes a long time and researchers are not allowed to do the things to humans that they can do to animals. The amount of information about epigenetic changes inherited by humans is likely to grow over time though.

Incidentally, several commenters here seem not to understand why epigenetic change and horizontal gene transfer are not Darwinian evolution. They seem to think that Darwinism just means “evolution.” It does not. Darwinism, as understood today (neo-Darwinism) is natural selection acting on random mutations of a life form’s genome. Epigenetics is non-random change due to identifiable causes. Horizontal gene transfer is the successful absorption of alien genes, not changes in the existing genes. But, for whatever reason, we don’t expect the misunderstandings to clear up any time soon.

See also: Epigenetic Learning Appears Confirmed In Nematodes Weismann Barrier Broken

Paper: Sperm Cells Take Up Genetic Material From Outside Themselves

Did you know that much of the diversity of the human brain results from epigenetics


Epigenetic change: Lamarck, wake up, you’re wanted in the conference room!

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One way to study epigenetics in humans might be to track the mutability of heritable traits on a group level that are exposed to selection pressure over time. For instance, changes in IQ among ethnic groups, like those cited here: Thomas Sowell on IQ and Race jstanley01
Bob O'h: There are no findings that have ever proven evolution to exist at all. There has not been one positive mutation ever witnessed. There is not one complete line of fossils and an absence of mutations as they take place. Put Darwinism through the scientific process, as it actually is believed to exist and prove Darwin right. This has never been done, since part of the process is dealing with something actually observable in nature. BobRyan
Earth to Bob O'H- Modern evolutionary thought still promotes the unscientific notion that evolution proceeds via blind, mindless and purposeless processes. There aren't any actual arguments that support it. There isn't even a methodology to test it. Modern evolutionary thought is in a sad state. Perhaps it is you who needs to learn what modern evolutionary thought is. ET
Darwinism, as understood today (neo-Darwinism) is natural selection acting on random mutations of a life form’s genome.
By that definition nobody who studies biology is a Darwinist, so you've created a straw man. Why do you keep on going on about it? Why not actually learn about what modern evolutionary thought is? Or is ID in such a poor state that you can't find arguments against actual evolutionary biology? Bob O'H

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