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Is there some kind of a world war on in nature?

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Until now, scientists were unable to prove that mammals use RNAi for killing viruses, but ironically, it was Ding’s earlier research into plants, nematodes and fruit flies that helped him find the key: viruses have been outwitting that innate protection in our cells by using proteins to suppress our virus-killing mechanism.

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As to the question in the OP:
Is there some kind of a world war on in nature (between viruses and higher organisms)?
Actually, contrary to popular opinion, the answer is NO to that question. For the vast majority of the times bacteria and viruses are found to be helping us in essential ways:
(Phage) Virus - Assembly Of A Nano-Machine - video http://www.metacafe.com/watch/4023122
Though most people think of viruses as being very harmful to humans, the fact is that the Bacteriophage (Bacteria Eater) virus, in the preceding video, is actually a very beneficial virus for man.
Bacteriophage Excerpt: Bacteriophages are among the most common biological entities on Earth,,,They have been used for over 60 years as an alternative to antibiotics in the former Soviet Union and Eastern Europe.[5] They are seen as a possible therapy against multi drug resistant strains of many bacteria.,,,development of phage therapy was largely abandoned in the West, but continued throughout 1940s in the former Soviet Union for treating bacterial infections, with widespread use including the soldiers in the Red Army—much of the literature was published in Russian or Georgian, and unavailable for many years in the West. Their use has continued since the end of the Cold War in Georgia and elsewhere in Eastern Europe.,,,In August, 2006 the United States Food and Drug Administration (FDA) approved using bacteriophages on cheese to kill the Listeria monocytogenes bacteria, giving them GRAS status (Generally Recognized As Safe).[10] In July 2007, the same bacteriophages were approved for use on all food products.[11] Government agencies in the West have for several years been looking to Georgia and the Former Soviet Union for help with exploiting phages for counteracting bioweapons and toxins, e.g., Anthrax, Botulism. - per wikipedia (Bacteriophage) Viruses in the gut protect from infection - 20 May 2013 Excerpt: Barr and his colleagues,, show that animal mucus — whether from humans, fish or corals — is loaded with bacteria-killing viruses called phages. These protect their hosts from infection by destroying incoming bacteria. In return, the phages are exposed to a steady torrent of microbes in which to reproduce. “It’s a unique form of symbiosis, between animals and viruses,” says Rotem Sorek, a microbial geneticist ,, “It’s groundbreaking,” adds Frederic Bushman, a microbiologist ,, “The idea that phage can be viewed as part of the innate immune system is original and exciting. http://www.nature.com/news/viruses-in-the-gut-protect-from-infection-1.13023 Viruses: A Pirate Phage Commandeers the Immune System of Bacteria - Feb. 27, 2013 Excerpt: The study provides the first evidence that this type of virus, the bacteriophage ("phage" for short), can acquire a wholly functional and adaptive immune system. The phage used the stolen immune system to disable -- and thus overcome -- the cholera bacteria's defense system against phages. Therefore, the phage can kill the cholera bacteria and multiply to produce more phage offspring, which can then kill more cholera bacteria. The study has dramatic implications for phage therapy,,, http://www.sciencedaily.com/releases/2013/02/130227134334.htm
The same is found for bacteria:
NIH Human Microbiome Project defines normal bacterial makeup of the body – June 13, 2012 Excerpt: Microbes inhabit just about every part of the human body, living on the skin, in the gut, and up the nose. Sometimes they cause sickness, but most of the time, microorganisms live in harmony with their human hosts, providing vital functions essential for human survival. http://www.nih.gov/news/health/jun2012/nhgri-13.htm
In fact it can be, and has been, argued that it is only in the few instances when something goes terribly wrong (via 'random' mutation and selection) with the original design that bacteria and viruses attack us:
We are living in a bacterial world, and it's impacting us more than previously thought - February 15, 2013 Excerpt: We often associate bacteria with disease-causing "germs" or pathogens, and bacteria are responsible for many diseases, such as tuberculosis, bubonic plague, and MRSA infections. But bacteria do many good things, too, and the recent research underlines the fact that animal life would not be the same without them.,,, I am,, convinced that the number of beneficial microbes, even very necessary microbes, is much, much greater than the number of pathogens." http://phys.org/news/2013-02-bacterial-world-impacting-previously-thought.html#ajTabs
Michael Behe defends the one 'overlooked' protein/protein binding site generated by the HIV virus (that he missed in his book 'Edge of Evolution), and that Abbie Smith and Ian Musgrave had found, by pointing out it is well within the 2 binding site limit he set in "The Edge Of Evolution" on this following site:
Response to Ian Musgrave's "Open Letter to Dr. Michael Behe," Part 4 "Yes, one overlooked protein-protein interaction developed, leading to a leaky cell membrane --- not something to crow about after 10^20 replications and a greatly enhanced mutation rate." http://behe.uncommondescent.com/2007/11/response-to-ian-musgraves-open-letter-to-dr-michael-behe-part-5/
In fact, I followed this debate very closely and it turns out the trivial gain of just one protein-protein binding site being generated for the non-living HIV virus, that the evolutionists were 'crowing' about, came at a staggering loss of complexity for the living host it invaded (People) with just that one trivial gain of a 'leaky cell membrane' in binding site complexity. Thus the 'evolution' of the virus clearly stayed within the principle of 'Genetic Entropy' (Sanford) since far more functional complexity was lost by the living human cells it invaded than was ever gained by the non-living HIV virus. A non-living virus which depends on those human cells to replicate in the first place. Moreover, while learning that HIV is a 'mutational powerhouse' which greatly outclasses the 'mutational firepower' of the entire spectrum of higher life-forms combined for millions of years, and about the devastating effect HIV has on humans with just that one trivial binding site being generated, I realized if evolution were actually the truth about how life came to be on Earth then the only 'life' that would be around would be extremely small organisms with the highest replication rate, and with the most 'mutational firepower', since only they would be the fittest to survive in the dog eat dog world where blind pitiless evolution rules and only the 'fittest' are allowed to survive. The logic of all this is nicely summed up here:
Richard Dawkins interview with a 'Darwinian' physician goes off track - video Excerpt: "I am amazed, Richard, that what we call metazoans, multi-celled organisms, have actually been able to evolve, and the reason [for amazement] is that bacteria and viruses replicate so quickly -- a few hours sometimes, they can reproduce themselves -- that they can evolve very, very quickly. And we're stuck with twenty years at least between generations. How is it that we resist infection when they can evolve so quickly to find ways around our defenses?" http://www.evolutionnews.org/2012/07/video_to_dawkin062031.html
So thus it is a very good thing that there is not 'some kind of a world war' going on between us viruses and bacteria, and that viruses and bacteria, for the vast majority of times, help us, for we would lose the the world war with them big time in very short order. Of related note to developing effective drugs against viruses and bacteria, using Dr. Behe's 2 protein-protein binding site limit derived in the 'Edge of Evolution', if a drug were developed that would require the generation of 3 novel protein binding sites by the virus or bacteria to overcome, then the drug would, according to Behe's 'Edge of Evolution', deal a death blow to the mutant virus, or bacteria, that was attacking us.
"The immediate, most important implication is that complexes with more than two different binding sites-ones that require three or more proteins-are beyond the edge of evolution, past what is biologically reasonable to expect Darwinian evolution to have accomplished in all of life in all of the billion-year history of the world. The reasoning is straightforward. The odds of getting two independent things right are the multiple of the odds of getting each right by itself. So, other things being equal, the likelihood of developing two binding sites in a protein complex would be the square of the probability for getting one: a double CCC, 10^20 times 10^20, which is 10^40. There have likely been fewer than 10^40 cells in the world in the last 4 billion years, so the odds are against a single event of this variety in the history of life. It is biologically unreasonable." - Michael Behe - The Edge of Evolution - page 146
But developing such a drug that takes advantage of the 'Edge of Evolution' is not as easy as it sounds. Here are a couple of example of how hard it is for humans to 'intelligently design' just one binding site:
Viral-Binding Protein Design Makes the Case for Intelligent Design! - Fazale Rana - June 2011 Excerpt: When considering this study, it is remarkable to note how much effort it took to design a protein that binds to a specific location on the hemagglutinin molecule. As biochemists Bryan Der and Brian Kuhlman point out while commenting on this work, the design of these proteins required: "...cutting-edge software developed by ~20 groups worldwide and 100,000 hours of highly parallel computing time. It also involved using a technique known as yeast display to screen candidate proteins and select those with high binding affinities, as well as x-ray crystallography to validate designs.2" If it takes this much work and intellectual input to create a single protein from scratch, is it really reasonable to think that undirected evolutionary processes could accomplish this task routinely? In other words, the researchers from the University of Washington and The Scripps Institute have unwittingly provided empirical evidence that the high-precision interactions required for PPIs requires intelligent agency to arise. http://www.reasons.org/viral-binding-protein-design-makes-case-intelligent-design-sick-cool Computer-designed proteins programmed to disarm variety of flu viruses - June 1, 2012 Excerpt: The research efforts, akin to docking a space station but on a molecular level, are made possible by computers that can describe the landscapes of forces involved on the submicroscopic scale.,, These maps were used to reprogram the design to achieve a more precise interaction between the inhibitor protein and the virus molecule. It also enabled the scientists, they said, "to leapfrog over bottlenecks" to improve the activity of the binder. http://phys.org/news/2012-06-computer-designed-proteins-variety-flu-viruses.html
bornagain77
October 11, 2013
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Nothing in biology makes sense in light of evolutionary theory.Mung
October 11, 2013
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