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Researchers: Life originated from simple fats, amino acids – but we will likely never know

fatty acids/Adela Rendón, CIC-BioGUNE

From ScienceDaily:

As they were able to see, the catalysis of the reaction took place when the fatty acids formed compartments. As they are in an aqueous medium, and due to the hydrophobic nature of lipids, they tend to join with each other and form closed compartments; in other words, they take on the function of a membrane; “at that time the membranes obviously weren’t biological but chemical ones,” explained Ruiz-Mirazo. In their experiments they were able to see that the conditions offered by these membranes are favourable for amino acids. “The Montpellier group had the prebiotic reactions of the formation of dipeptides very well characterised, so they were able to see that this reaction took place more efficiently in the presence of fatty acids,” he added.

In his studies, in addition to the experimental work, Ruiz-Mirazo is working in another two spheres so in the end he is studying the origin of life from three pillars or perspectives: “firstly, we have the experimental field; another is based on theoretical models and computational simulations, which we use to analyse the results obtained in the experiments, and the third is a little broader, because we are studying from the philosophical viewpoint what life is, the influence that the conception held about life exerts on the experimental field, since each conception leads you to carry out a specific type of experiment,” he explained. “These three methodologies mutually feed each other: an idea that may emerge in the philosophical analysis leads you to carry out a new simulation, and the results of the simulations mark out the path for designing the experiments. Or the other way round. Most likely we will never manage to find the answer to how life began, but we are working on it: all of us living beings on Earth have the same origin and we want to know how it happened.” Paper. (public access) – Sara Murillo-Sánchez, Damien Beaufils, Juan Manuel González Mañas, Robert Pascal, Kepa Ruiz-Mirazo. Fatty acids’ double role in the prebiotic formation of a hydrophobic dipeptide. Chem. Sci., 2016; 7 (5): 3406 DOI: 10.1039/C5SC04796JMore.

One question that simple origin of life theories consistently fail to provide an answer to is, why is spontaneous generation not happening today? A Darwinian once tried telling us that natural selection would weed out “more primitive” life forms just starting to come into existence. But that doesn’t make any sense because there is no evidence that “more primitive” is or ever has been a disadvantage in terms of mere survival. [added:] Most likely, the opposite. We simply do not have evidence that such life forms exist or ever have existed free in nature.

Note: The researchers say,  “Most likely we will never manage to find the answer to how life began, but we are working on it: all of us living beings on Earth have the same origin and we want to know how it happened.” Isn’t this a bit confusing? We likely won’t find out but we are working on it anyway… so why not work on something we can find out?

See also: Life on Earth at 4.1 billion years ago? Origin of life: Something momentous happened 4.5 bya that is *not at all* like what happens today. And no one knows a thing about it. But there are plenty of stories.

Life can arise naturally from chemistry!

Researchers: Bacteria fossils predate the origin of oxygen

Rob Sheldon: Why the sulfur-based life forms never amounted to much

Welcome to “RNA world,” the five-star hotel of origin-of-life theories

What we know and don’t know about the origin of life

Follow UD News at Twitter!

NEWS asks, 'why is spontaneous generation not happening today?' All the ingredients for life are present, and the physical forces causing those ingredients to react are still with us. So the question as to why it is not happening today is weird; it surely is! However, the evolved bacteria, plants and animals, that are on the planet today do not take kindly to new cmpetition, and rapidly absorb any new kind of competitor. In the ancient oceans new environments were far less crowded, and competition far less robust, the perfect place for life to evolve. rvb8
With respect to "fats" lipids, see also this if you missed it: http://www.evolutionnews.org/2017/01/interview_bioch103408.html A professor who studied lipids for 30 years says they're phenomenally complex and can't imagine how they could have evolved from original theoretically simple forms. He won't give his name however. Wonder why? es58
BA77: That video of James Tour is remarkably good. I don't know how anyone can believe that life 'just happened' after watching it. Thanks for reminding us of it. PaV
They say:
Most likely we will never manage to find the answer to how life began, but we are working on it: all of us living beings on Earth have the same origin and we want to know how it happened.”
So, they don't think they'll ever know what the answer to how life began, yet, they still want to work at it. Remember how any mention that God designed life was a "science stopper." Obviously, that was, and is, just a bogus argument. These intrepid experimenters have proven that to us. PaV
News @3: Agree. I couldn't have said it better. Thank you both. Have a good weekend. Dionisio
Once again, thanks so much, bornagain77, for the wonderful reference material. A newser can only keep up with, well, news, but you bring it to life for serious thinkers. - d. News
Darwinism and Neo-Darwinism are faith-based philosophical worldviews. No shame in that. I just wish they would admit it. It would free them from having to constantly defend the false notion that evolution is based solely on empirical evidence. That has never been the case. Truth Will Set You Free
James Tour puts these atheistic pipe dreams in proper context:
Origin of Life: An Inside Story - Professor James Tour – May 1, 2016 Excerpt: “All right, now let’s assemble the Dream Team. We’ve got good professors here, so let’s assemble the Dream Team. Let’s further assume that the world’s top 100 synthetic chemists, top 100 biochemists and top 100 evolutionary biologists combined forces into a limitlessly funded Dream Team. The Dream Team has all the carbohydrates, lipids, amino acids and nucleic acids stored in freezers in their laboratories… All of them are in 100% enantiomer purity. [Let’s] even give the team all the reagents they wish, the most advanced laboratories, and the analytical facilities, and complete scientific literature, and synthetic and natural non-living coupling agents. Mobilize the Dream Team to assemble the building blocks into a living system – nothing complex, just a single cell. The members scratch their heads and walk away, frustrated… So let’s help the Dream Team out by providing the polymerized forms: polypeptides, all the enzymes they desire, the polysaccharides, DNA and RNA in any sequence they desire, cleanly assembled. The level of sophistication in even the simplest of possible living cells is so chemically complex that we are even more clueless now than with anything discussed regarding prebiotic chemistry or macroevolution. The Dream Team will not know where to start. Moving all this off Earth does not solve the problem, because our physical laws are universal. You see the problem for the chemists? Welcome to my world. This is what I’m confronted with, every day.“ James Tour – one of the top ten leading chemists in the world The Origin of Life: An Inside Story - March 2016 Lecture video https://www.youtube.com/watch?v=_zQXgJ-dXM4
A few more notes:
Suzan Mazur: Origin of life shifting to “nonmaterial events”? - December 15, 2013 Excerpt: The first paradox is the tendency of organic matter to devolve and to give tar. If you can avoid that, you can start to try to assemble things that are not tarry, but then you encounter the water problem, which is related to the fact that every interesting bond that you want to make is unstable, thermodynamically, with respect to water. If you can solve that problem, you have the problem of entropy, that any of the building blocks are going to be present in a low concentration; therefore, to assemble a large number of those building blocks, you get a gene-like RNA — 100 nucleotides long — that fights entropy. And the fourth problem is that even if you can solve the entropy problem, you have a paradox that RNA enzymes, which are maybe catalytically active, are more likely to be active in the sense that destroys RNA rather than creates RNA. https://uncommondesc.wpengine.com/origin-of-life/origin-of-life-shifting-to-nonmaterial-events/ RNA world: Chemists Propose a Seemingly Unlikely Environment for the Origin of Life - February 27, 2013 Excerpt: Benner and his colleagues consider three major problems with the RNA-world model: *The "asphalt problem": Organic reactions often produce unreactive byproducts. These byproducts are a mixture of pieces of the product or polymerization of the product, but are chemically insignificant and otherwise unpromising. Hence the metaphor of "asphalt." Typically, avoiding the production of such byproducts requires very specific and controlled conditions, or post-reaction purification steps. *The "water problem": Many of the bonds in RNA will undergo hydrolysis. This occurs when water reacts with the bond, causing it to break apart. In a lab, the problem is easily addressed by using a different solvent. However, the environment of the early Earth could not draw on the resource of various organic solvents. *The "impossible bond problem": The authors refer here to the difficulty in forming certain bonds in RNA. Usually this follows from thermodynamic issues that prohibit bonds from spontaneously forming. Conspicuously missing from the authors' list of critiques are the "chirality problem" and the "information problem." Later in the paper, however, they concede that their model does not solve the enigma of chirality, and they allude to a potential "fatal flaw" in their proposition, namely that the kinds of RNA molecules that catalyze the destruction of RNA are more likely to emerge than RNA molecules that catalyze the synthesis of RNA. - http://www.evolutionnews.org/2013/02/death_valley_da068661.html Chemistry by Chance: A Formula for Non-Life by Charles McCombs, Ph.D. Excerpt: The following eight obstacles in chemistry ensure that life by chance is untenable. 1. The Problem of Unreactivity 2. The Problem of Ionization 3. The Problem of Mass Action 4. The Problem of Reactivity 5. The Problem of Selectivity 6. The Problem of Solubility 7. The Problem of Sugar 8. The Problem of Chirality The chemical control needed for the formation of a specific sequence in a polymer chain is just not possible through random chance. The synthesis of proteins and DNA/RNA in the laboratory requires the chemist to control the reaction conditions, to thoroughly understand the reactivity and selectivity of each component, and to carefully control the order of addition of the components as the chain is building in size. http://www.icr.org/article/chemistry-by-chance-formula-for-non-life/ Abiogenesis: The Faith and the Facts - Dr. Edward Peltzer - video http://www.youtube.com/watch?v=6xj4UH0RwcM Dr. Edward Peltzer explores the possibilities that 1. Life is the result of unguided chemical reactions and random processes 2. Life is the result of purposeful physical laws and initial conditions 3. The laws of nature and fine-tuning of the initial conditions are sufficient to account for the origin of life 4. natural processes alone prohibit the origin of life After reviewing the evidence for each option Dr. Peltzer comes to the conclusion that chemical cross-reactions, including the Maillard reaction, would have prevented a purely naturalistic origin of life. His research thus supports the Law of Biogenesis, that life proceeds only from pre-existing life.
Of supplemental note: Here is a recent article by Dr. Tour on Chiral Induced Spin Selectivity (CISS) :
Chiral Induced Spin Selectivity (CISS) James Tour – December 2016 Excerpt: Kwabena Boahen estimated that a microelectronics processor functioning with the capacity of a human brain would need at least ten megawatts to operate. This is equivalent to the output of a small hydroelectric power plant. The human brain needs only about ten watts.6 Might CISS (Chiral Induced Spin Selectivity) help to explain biology’s secret to efficiency? http://inference-review.com/article/chiral-induced-spin-selectivity
Perhaps if men really want to know where life came from they ought to look to the one who defeated death on the cross? Video, Article & Verse:
Shroud of Turin: From discovery of Photographic Negative, to 3D Information, to Quantum Hologram https://www.youtube.com/watch?v=F-TL4QOCiis&index=5&list=PLtAP1KN7ahia8hmDlCYEKifQ8n65oNpQ5 Astonishing discovery at Christ's tomb supports Turin Shroud - NOV 26TH 2016 Excerpt: The first attempts made to reproduce the face on the Shroud by radiation, used a CO2 laser which produced an image on a linen fabric that is similar at a macroscopic level. However, microscopic analysis showed a coloring that is too deep and many charred linen threads, features that are incompatible with the Shroud image. Instead, the results of ENEA “show that a short and intense burst of VUV directional radiation can color a linen cloth so as to reproduce many of the peculiar characteristics of the body image on the Shroud of Turin, including shades of color, the surface color of the fibrils of the outer linen fabric, and the absence of fluorescence”. 'However, Enea scientists warn, "it should be noted that the total power of VUV radiations required to instantly color the surface of linen that corresponds to a human of average height, body surface area equal to = 2000 MW/cm2 17000 cm2 = 34 thousand billion watts makes it impractical today to reproduce the entire Shroud image using a single laser excimer, since this power cannot be produced by any VUV light source built to date (the most powerful available on the market come to several billion watts )”. Comment The ENEA study of the Holy Shroud of Turin concluded that it would take 34 Thousand Billion Watts of VUV radiations to make the image on the shroud. This output of electromagnetic energy remains beyond human technology. https://www.ewtn.co.uk/news/latest/astonishing-discovery-at-christ-s-tomb-supports-turin-shroud John 1:3-4 Through Him all things were made, and without Him nothing was made that has been made. In Him was life, and that life was the light of men.

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