Materialism—the view that nature is fundamentally constituted by matter outside and independent of mind—is a metaphysics, in that it makes statements about what nature essentially is. As such, it is also a theoretical inference: we cannot empirically observe matter outside and independent of mind, for we are forever locked in mind. All we can observe are the contents of perception, which are inherently mental. Even the output of measurement instruments is only accessible to us insofar as it is mentally perceived. – Bernardo Kastrup, “Why Materialism Is a Dead-end” at Iai.tv (November 15, 2019)News, “Science-based reasons why materialism is a dead end” at Mind Matters News
Science is a world of ideas, not things. What we observe is by its very nature, mental, not physical.