Genomics Intelligent Design

Tim Standish on those five new alternate genetic codes in bacteria: It’s way more complicated than they are making out.

Standish: Changing codon meaning isn’t merely a tweak. As one of the authors notes, “It’s just mind-boggling that an organism could survive that.” But he is dead wrong when he says, “Stop codon shifts are considerably less ‘dramatic’”. Changing a stop codon seems significantly more challenging than changing any other codon meaning because the mechanism for stop codon recognition is totally different and involves more than RNA-RNA interactions.