Fixation: the neutral theory’s Achilles’ heel?
The neutral theory of evolution appears to have won out over its rival, neo-Darwinian selection theory (see here and here). However, the neutral theory makes a very specific prediction about the rate at which mutations are fixed in a population, which I think warrants more testing and scrutiny. The evidence for this prediction which I’ve seen to date is frankly underwhelming. What is the neutral theory of evolution? Let’s begin with a few definitions. What is the neutral theory of evolution? Here’s a short definition given by Professor Terry Speed, formerly of Berkeley University: The Neutral Theory of Molecular Evolution (Kimura) states, in essence, that most of the variation seen at the molecular level is selectively neutral — that is, Read More ›