From RealClearScience: “Animal models are limited in their ability to mimic the extremely complex process of human carcinogenesis, physiology and progression,” McMaster University scientists Isabella Mak, Nathan Evaniew, and Michelle Ghert, wrote in 2014. “Therefore the safety and efficacy identified in animal studies is generally not translated to human trials.” While the systems that regulate gene activity are generally the same in mice and humans, there are key biological differences in other areas that prevent successful results from applying to humans. Transcription factor binding sites, where information is passed on, differ for between 41 and 89 percent of the genes that our species share. Moreover, unlike humans, mice used in studies are often highly inbred. The mouse immune system is Read More ›