Epigenetics: How many methylation patterns can be attributed to ethnic ancestry?
From Anna Azvolinsky at The Scientist: In a study published last week (January 3) in eLife, Burchard and colleagues showed that about 75 percent of methylation signatures could be explained by the children’s genetic ancestry. The other 25 percent, however, is likely due to social or environmental factors that co-vary with self-identified race/ethnicity. The study is among the first to probe how the epigenome is influenced by genetic ancestry. Additional investigations are needed to better understand to what extent race and ethnicity are interchangeable with genetic ancestry, experts say. … It is challenging to draw conclusions from methylation analyses like this one because “a lot of the variation can be explained by background genetic variation of individuals,” noted Conley. In Read More ›