Ann Gauger: The key issue around whether evolution is random

_{Denyse O'Leary

February 17, 2018

Darwinism, Evolution, Intelligent Design}

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Further to the question of whether evolution is random, a reader draws our attention to a 2015 post by Ann Gauger at ENST:

Mutation, drift, selection, and environmental change all play a role. Three out of these four forces are random, without regard for the needs of the organism. Even selection can be random in its direction, depending on the environment.

So tell me. Is evolution random? Most of the processes at work definitely are. Certainly evolution won’t make steady progress in one direction without some other factor at work. What that factor might be remains to be seen. I personally do not think a material explanation will be found, because any process to guide evolution in a purposeful way will require a purposeful designer to create it. (2015)More.

It’s hard to evaluate the options honestly if design cannot be considered in principle.

See also: Researchers: Simple traits may not have simple predictable evolutionary paths Paper: This is in stark contrast to studies of microbial, viral, and immune system selection, for which evolution seems to be highly predictable (13). Why this is the case, when it is not so in organisms such as stick insects and others, is a new challenge for evolutionary biologists.

Comments

Evolution is random to any particular problem to solve, not completely random. This is because the process of evolution cannot conceive of problems like we can.critical rationalist_{February 20, 2018
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Random in this case means happenstance, accidental, not planed. Mutations just happen. But as bornagain77 mentioned above that seems to be untenable given the evidence.ET_{February 19, 2018
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The vast majority of mutations are now shown not to be random as Darwinists had presupposed,,,
New Research Elucidates Directed Mutation Mechanisms - Cornelius Hunter - January 7, 2013 Excerpt: mutations don’t occur randomly in the genome, but rather in the genes where they can help to address the challenge. But there is more. The gene’s single stranded DNA has certain coils and loops which expose only some of the gene’s nucleotides to mutation. So not only are certain genes targeted for mutation, but certain nucleotides within those genes are targeted in what is referred to as directed mutations.,,, These findings contradict evolution’s prediction that mutations are random with respect to need and sometimes just happen to occur in the right place at the right time.,,, http://darwins-god.blogspot.com/2013/01/news-research-elucidates-directed.html "It is difficult (if not impossible) to find a genome change operator that is truly random in its action within the DNA of the cell where it works. All careful studies of mutagenesis find statistically significant non-random patterns” James Shapiro - Evolution: A View From The 21st Century - (Page 82) How life changes itself: the Read-Write (RW) genome. – 2013 Excerpt: Research dating back to the 1930s has shown that genetic change is the result of cell-mediated processes, not simply accidents or damage to the DNA. This cell-active view of genome change applies to all scales of DNA sequence variation, from point mutations to large-scale genome rearrangements and whole genome duplications (WGDs). This conceptual change to active cell inscriptions controlling RW genome functions has profound implications for all areas of the life sciences. http://www.ncbi.nlm.nih.gov/pubmed/23876611 WHAT SCIENTIFIC IDEA IS READY FOR RETIREMENT? Fully Random Mutations – Kevin Kelly – 2014 Excerpt: What is commonly called “random mutation” does not in fact occur in a mathematically random pattern. The process of genetic mutation is extremely complex, with multiple pathways, involving more than one system. Current research suggests most spontaneous mutations occur as errors in the repair process for damaged DNA. Neither the damage nor the errors in repair have been shown to be random in where they occur, how they occur, or when they occur. Rather, the idea that mutations are random is simply a widely held assumption by non-specialists and even many teachers of biology. There is no direct evidence for it. On the contrary, there’s much evidence that genetic mutation vary in patterns. For instance it is pretty much accepted that mutation rates increase or decrease as stress on the cells increases or decreases. These variable rates of mutation include mutations induced by stress from an organism’s predators and competition, and as well as increased mutations brought on by environmental and epigenetic factors. Mutations have also been shown to have a higher chance of occurring near a place in DNA where mutations have already occurred, creating mutation hotspot clusters—a non-random pattern. http://edge.org/response-detail/25264
Secondly, although Darwinists presupposed that biological molecules would be based on ‘random’ Brownian motion and to therefore be “randomly colliding with each other”’,,,,
No, Scientists in Darwin’s Day Did Not Grasp the Complexity of the Cell; Not Even Close – Casey Luskin – June 6, 2013 Excerpt: We have always underestimated cells. Undoubtedly we still do today. But at least we are no longer as naïve as we were when I was a graduate student in the 1960s. Then, most of us viewed cells as containing a giant set of second-order reactions: molecules A and B were thought to diffuse freely, randomly colliding with each other to produce molecule AB — and likewise for the many other molecules that interact with each other inside a cell. This seemed reasonable because, as we had learned from studying physical chemistry, motions at the scale of molecules are incredibly rapid. Consider an enzyme, for example. If its substrate molecule is present at a concentration of 0.5mM,which is only one substrate molecule for every 105 water molecules, the enzyme’s active site will randomly collide with about 500,000 molecules of substrate per second. And a typical globular protein will be spinning to and fro, turning about various axes at rates corresponding to a million rotations per second. But, as it turns out, we can walk and we can talk because the chemistry that makes life possible is much more elaborate and sophisticated than anything we students had ever considered. Proteins make up most of the dry mass of a cell. But instead of a cell dominated by randomly colliding individual protein molecules, we now know that nearly every major process in a cell is carried out by assemblies of 10 or more protein molecules. And, as it carries out its biological functions, each of these protein assemblies interacts with several other large complexes of proteins. Indeed, the entire cell can be viewed as a factory that contains an elaborate network of interlocking assembly lines, each of which is composed of a set of large protein machines.” – Bruce Alberts, “The Cell as a Collection of Protein Machines: Preparing the Next Generation of Molecular Biologists,” Cell, 92 (February 6, 1998): 291-294) Editor-in-Chief of Science (2009-2013). Dr Alberts served two six-year terms as the president of the National Academy of Sciences http://www.evolutionnews.org/2013/06/did_scientists_072871.html Flailing Blindly: The Pseudoscience of Josh Rosenau and Carl Zimmer – Jonathan Wells – April 17, 2014 Excerpt: The new animation (like the old) also includes a kinesin molecule hauling a vesicle, but this time the kinesin’s movements are characterized (in Zimmer’s words) by
“barely constrained randomness. Every now and then, a tiny molecule loaded with fuel binds to one of the kinesin “feet.” It delivers a jolt of energy, causing that foot to leap off the molecular cable and flail wildly, pulling hard on the foot that’s still anchored. Eventually, the gyrating foot stumbles into contact again with the cable, locking on once more — and advancing the vesicle a tiny step forward. This updated movie offers a better way to picture our most intricate inner workings…. In the 2006 version, we can’t help seeing intention in the smooth movements of the molecules; it’s as if they’re trying to get from one place to another. In reality, however, the parts of our cells don’t operate with the precise movements of the springs and gears of a clock. They flail blindly in the crowd.”
But that’s not what the biological evidence shows. In fact, kinesin moves quickly, with precise movements, to get from one place to another. A kinesin molecule takes one 8-nanometer “step” along a microtubule for every high-energy ATP molecule it uses, and it uses about 80 ATPs per second. On the scale of a living cell, this movement is very fast. To visualize it on a macroscopic scale, imagine a microtubule as a one-lane road and the kinesin molecule as an automobile. The kinesin would be traveling over 200 miles per hour! https://iconsofevolution.com/flailing-blindly/
,,,Although Darwinists presupposed that biological molecules would be based on ‘random’ Brownian motion and to therefore be “randomly colliding with each other”, the fact of the matter is that Brownian motion in biology is, for all practical purposes, not to be found in biological life. In fact, it is now found that “living organisms have a certain order. A structure to them that’s very different from the random thermodynamic jostling of atoms and molecules in inanimate matter of the same complexity. In fact, living matter seems to behave in its order and its structure just like inanimate cooled down to near absolute zero.”
Jim Al-Khalili, at the 2:30 minute mark of the following video states, “,,and Physicists and Chemists have had a long time to try and get use to it (Quantum Mechanics). Biologists, on the other hand have got off lightly in my view. They are very happy with their balls and sticks models of molecules. The balls are the atoms. The sticks are the bonds between the atoms. And when they can’t build them physically in the lab nowadays they have very powerful computers that will simulate a huge molecule.,, It doesn’t really require much in the way of quantum mechanics in the way to explain it.” At the 6:52 minute mark of the video, Jim Al-Khalili goes on to state: “To paraphrase, (Erwin Schrödinger in his book “What Is Life”), he says at the molecular level living organisms have a certain order. A structure to them that’s very different from the random thermodynamic jostling of atoms and molecules in inanimate matter of the same complexity. In fact, living matter seems to behave in its order and its structure just like inanimate cooled down to near absolute zero. Where quantum effects play a very important role. There is something special about the structure, about the order, inside a living cell. So Schrodinger speculated that maybe quantum mechanics plays a role in life”. Jim Al-Khalili – Quantum biology – video https://www.youtube.com/watch?v=zOzCkeTPR3Q Quantum coherent-like state observed in a biological protein for the first time – October 13, 2015 Excerpt: If you take certain atoms and make them almost as cold as they possibly can be, the atoms will fuse into a collective low-energy quantum state called a Bose-Einstein condensate. In 1968 physicist Herbert Fröhlich predicted that a similar process at a much higher temperature could concentrate all of the vibrational energy in a biological protein into its lowest-frequency vibrational mode. Now scientists in Sweden and Germany have the first experimental evidence of such so-called Fröhlich condensation (in proteins).,,, For their protein, the researchers chose the enzyme lysozyme, .,,, The real-world support for Fröhlich’s theory took so long to obtain because of the technical challenges of the experiment, Katona said. https://phys.org/news/2015-10-quantum-coherent-like-state-biological-protein.html Darwinian Materialism vs Quantum Biology – video https://www.youtube.com/watch?v=LHdD2Am1g5Y
Simply put, due to advances in quantum biology, Darwinian evolution, particularly the reductive materialism upon which Darwinian evolution is based, has now been empirically falsified. If Darwinian evolution were a normal science this should be the death blow to the theory. But alas, Darwinism never really was a normal discipline of science in the first place:
Darwinian Evolution: A Pseudoscience based on Unrestrained Imagination and Bad Liberal Theology - video https://youtu.be/KeDi6gUMQJQ
Verse:
2 Corinthians 10:5 Casting down imaginations, and every high thing that exalteth itself against the knowledge of God, and bringing into captivity every thought to the obedience of Christ;
bornagain77_{February 17, 2018
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Are mutations random? Some or very few of them... Hot-spots are an indication that at least some or the majority of mutations could be not necessarily random, but their occurrence could be somewhat limited... Now, if one looks deeper in the realm of quantum mechanics governed mitosis, then mutations look nothing like a system designed by luck but more like a system that was designed to work perfectly that doesn't always live up to the expectation..J-Mac_{February 17, 2018
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