Here.
In this way, the researchers looked back at selection events that occurred up to 500,000 years ago, revealing the evolutionary forces that shaped the dawn of modern humans, thought to be around 200,000 years ago. Most previous methods for uncovering such changes reach back only about 30,000 years, says Stephen Schaffner, a computational biologist at the Broad Institute in Cambridge, Massachusetts.
The analytical approach that Tang’s team used is promising, he adds. “It’s treating all kinds of selection in a uniform framework, and it’s also treating different eras of selection in a more or less uniform way.” But Schaffner says that further research is needed to confirm that the method is broadly applicable.
Still, even the most powerful genomic-analysis methods can be limited by the vagaries of history. Asian and European people descended from a small number of people who left Africa around 60,000 years ago …
The article is a classic in that it is replete with Darwinbabble which gets more annoying as its gets more obviously useless.
For one thing, Alzheimer is probably mainly noticed in humans. If an alpha wolf or bull moose gets a little ditzy, he is probably just replaced by an ambitious subordinate.
That’s not quite what happens when we must, often with considerable reluctance, accept that a loved one is experiencing long term brain challenges. For example, a typical checklist might include:
Moderate Alzheimer’s is typically the longest stage and can last for many years. As the disease progresses, the person with Alzheimer’s will require a greater level of care.
You may notice the person with Alzheimer’s confusing words, getting frustrated or angry, or acting in unexpected ways, such as refusing to bathe. Damage to nerve cells in the brain can make it difficult to express thoughts and perform routine tasks.
At this point, symptoms will be noticeable to others and may include:
– Forgetfulness of events or about one’s own personal history
– Feeling moody or withdrawn, especially in socially or mentally challenging situations
– Being unable to recall their own address or telephone number or the high school or college from which they graduated
One must already be a human being to have these kinds of problems. Where is the evolution, exactly?
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