Another Key Evidence For Evolution is Getting Squashed

Here's a interesting talk by Dr. John Sanford. Starting at the 17 minute mark going to the 22 minute mark, he relates how slightly detrimental mutations, that accumulate each time a cell divides, are the primary reason why our physical/material bodies grow old and die.

John Sanford on (Genetic Entropy) Down - Not Up 2-4-2012 (at Loma Linda University) - video http://www.youtube.com/watch?v=PHsu94HQrL0

Notes from video:

*3 new mutations every time a cell divides in your body * Average cell of 15 year old has up to 6000 mutations *Average cell of 60 year old has 40,000 mutations Reproductive cells are 'designed' so that, early on in development, they are 'set aside' and thus they do not accumulate mutations as the rest of the cells of our bodies do. Regardless of this protective barrier against the accumulation of slightly detrimental mutations still we find that,,, *60-175 mutations are passed on to each new generation.

Interestingly, this ‘slightly detrimental’ mutation rate of 60 to 175 per generation is far greater than even what evolutionists agree is an acceptable mutation rate since detrimental mutations will accumulate far faster than ‘natural selection’ (death) can eliminate them from the population:

Human evolution or extinction - acceptable mutation rate per generation (with clips from Dr. John Sanford) - video http://www.youtube.com/watch?v=aC_NyFZG7pM Beyond A 'Speed Limit' On Mutations, Species Risk Extinction Excerpt: Shakhnovich's group found that for most organisms, including viruses and bacteria, an organism's rate of genome mutation must stay below 6 mutations per genome per generation to prevent the accumulation of too many potentially lethal changes in genetic material. http://www.sciencedaily.com/releases/2007/10/071001172753.htm

Music and verse:

Mandisa - Esther - Born For This - music video http://www.youtube.com/watch?v=ZxFCber4TDo Psalm 139:13 For You formed my inward parts; You wove me in my mother's womb.

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a few 'inconvenient truths':

Alexander Tsiaras: Conception to birth -- visualized http://www.youtube.com/watch?v=fKyljukBE70 Mathematician Alexander Tsiaras on Human Development: "It's a Mystery, It's Magic, It's Divinity" - March 2012 Excerpt: 'The magic of the mechanisms inside each genetic structure saying exactly where that nerve cell should go, the complexity of these, the mathematical models on how these things are indeed done, are beyond human comprehension. Even though I am a mathematician, I look at this with the marvel of how do these instruction sets not make these mistakes as they build what is us. It's a mystery, it's magic, it's divinity.' http://www.evolutionnews.org/2012/03/mathematician_a057741.html A Piece from the Developmental Symphony - February 2012 Excerpt: Embryonic development is an astounding process that seems to happen "automatically.",,, The timing of each step is too precise and the complexity is too intricate to assume that these processes are the mere accumulation by happenstance of changes to regulatory genes. Each gene plays its role at a certain time, and like a symphony, each is activated and silenced in turn such that the final result is a grand performance of orchestrated effort that could only have occurred through design. http://www.evolutionnews.org/2012/02/a_piece_from_th055921.html Understanding Ontogenetic Depth, Part II: Natural Selection Is a Harsh Mistress - Paul Nelson - April 7, 2011 http://www.evolutionnews.org/2011/04/understanding_ontogenetic_dept_1045581.html Modern Synthesis of Neo-Darwinism Is Dead - No Evidence For Body Plan Morphogenesis From Embryonic Mutations - Paul Nelson - video http://www.metacafe.com/watch/5548184/modern_synthesis_of_neo_darwinism_is_dead_paul_nelson/ The mouse is not enough - February 2011 Excerpt: Richard Behringer, who studies mammalian embryogenesis at the MD Anderson Cancer Center in Texas said, “There is no ‘correct’ system. Each species is unique and uses its own tailored mechanisms to achieve development. By only studying one species (eg, the mouse), naive scientists believe that it represents all mammals.” http://www.the-scientist.com/news/display/57986/ Revisiting Those Early Developmental Stages: A Response to PZ Myers - Jonathan M. June 22, 2011 Excerpt: Let's take an illustrative example. Anurans and urodeles are both modern amphibian groups which we would consider to be closely related. However, there is significant difference in the source of their primordial germ cells. For instance, in urodeles, they arise from unspecific ectodermal cells at the blastula stage; whereas, in anurans, they arise from specific cells of endodermal origin, the cells possessing cytoplasmic granules that originated in the unfertilized egg. Now, here's the conundrum. The difference relates to organs of extreme importance -- i.e. the germ cells. The difference is not only substantial, but it occurs extremely early in development. http://www.evolutionnews.org/2011/06/revisiting_those_early_develop047571.html

Here is a excellent deconstruction of PZ Myer's favorite Icon Of Evolution (PZ named his, ahem, 'science' blog after it!);

Challenging the Precious Pharyngula - Casey Luskin - July 2011 http://www.evolutionnews.org/2011/07/challenging_the_precious_phary048291.html Icons of Evolution 10th Anniversary: Haeckel's Embryos - January 2011 - video http://www.youtube.com/watch?v=W0kHPw3LaG8

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