Intelligent Design

Larry Moran is a Desperate Man

Spread the love

Larry Moran is desperate.  He said I do not understand Darwinism.  I called him out and challenged him to demonstrate his claim.  He has now put up two posts in response, and they both fail miserably.

In the first post he flails about over the term “Darwinism” and says I mistakenly equate that term with “Neo-Darwinism” and the “Modern Synthesis.”  As evidence of my confusion he points to the UD glossary.  But that very glossary entry states that on this site we use the term “Darwinism” as shorthand for Neo-Darwinism or the modern synthesis, and then goes on to define those terms.

Note that Larry does not say UD’s definition of Neo-Darwinism or the modern synthesis is wrong.*  He says that when I use the word “Darwinism” as shorthand for Neo-Darwinism, it proves I don’t understand the difference between those two terms.  Astoundingly, the very glossary entry he points to proves him wrong.

In the second post he jumps on his favorite hobby horse, junk DNA:

He [i.e., Arrington] said that “Darwinists” predicted junk DNA and he states clearly that junk DNA is supposed to be “practically irrefutable evidence for the Darwinian hypothesis.”   But, as most Sandwalk readers know, nobody predicted junk DNA, certainly not Darwinists. 

(Emphasis added)

No Darwinist ever said the theory predicts junk DNA?  What about world famous Darwinist Francis Collins:

Darwin’s theory predicts that mutations that do not affect function, (namely, those located in “junk DNA” ) will accumulate steadily over time. Mutations in the coding region of genes, however, are expected to be observed less frequently, and only a rare such event will provide a selective advantage and be retained during the evolutionary process.” That is exactly what is observed.

Francis Collins, The Language of God, 2006

How about world famous Darwinist Jerry A. Coyne:

Perfect design would truly be the sign of a skilled and intelligent designer. Imperfect design is the mark of evolution; in fact, it’s precisely what we expect from evolution. . . .when a trait is no longer used or becomes reduced, the genes that make it don’t instantly disappear from the genome: Evolution strops their action by inactivating them, not snipping them out of the DNA. From this we can make a prediction. We expect to find, in the genomes of many species, silenced, or ‘dead,’ genes: genes that once were useful but re no longer intact or expressed. In other words, there should be vestigial genes. . . . the evolutionary prediction that we’ll find pseudogenes has been fulfilled – amply. Virtually ever species harbors dead genes, many of them still active in its relatives. This implies that some of those genes were also active in a common ancestor, and were killed off in some descendants but not in others. Out of about thirty thousand genes, for example, we humans carry more than two thousand pseudogenes. Our genome, – and that of other species – are truly well populated graveyards of dead genes

Jerry Coyne, Why Evolution is True, 2009

Examples could be multiplied, but you get the picture.

How embarrassing that biologist Larry has to be schooled on this subject by a lawyer.  Ouch.  That’s gotta smart.

Finally, notice how Larry lies about what I said just a few short paragraphs after he quotes me.  First he quotes me:

For years Darwinists touted “junk DNA” as not just any evidence but powerful, practically irrefutable evidence for the Darwinian hypothesis. ID proponents disagreed and argued that the evidence would ultimately demonstrate function.  Not only did both hypotheses make testable predictions, the Darwinist prediction turned out to be false and the ID prediction turned out to be confirmed.

Yes, I did write that.

Now notice Larry’s distortion later in the post:

Barry Arrington says that Darwinism predicted junk DNA and that junk DNA is strong evidence of the Darwinian hypothesis

No, I did not say that Darwinism predicted junk DNA.  I said Darwinists said the theory predicted junk DNA, and as I demonstrated above, they did.  And no, I did not say that junk DNA is strong evidence for the Darwinian hypothesis.  Those same Darwinists made that claim.  I said exactly the opposite, i.e., that ID proponents disagreed.

Larry, I have a question for you.  Why do you think making obviously false statements helps your case?  I’m not one of your poor captive students whom you can bully and give failing marks if I don’t toe your line.  This is not your classroom.  You can’t just make up facts to suit you as you go.

Things are not looking good for you Larry.  Two blog posts in and you have yet to provide a smidgen of evidence for your claim.

 

_________________

*To be sure, as is his wont, he engages is some genetic fallacy smears, but he never says a single word of the UD definition is wrong.

89 Replies to “Larry Moran is a Desperate Man

  1. 1
    Andre says:

    Barry

    To hop onto the Junk DNA Band Wagon here is high priest Dawkins….

    “It stretches even their creative ingenuity to make a convincing reason why an intelligent designer should have created a pseudogene — a gene that does absolutely nothing and gives every appearance of being a superannuated version of a gene that used to do something — unless he was deliberately setting out to fool us…

    Leaving pseudogenes aside, it is a remarkable fact that the greater part (95 percent in the case of humans) of the genome might as well not be there, for all the difference it makes.”

  2. 2
    NickMatzke_UD says:

    Barry,

    What you aren’t getting is that, in the way the term ‘Darwinists’ was traditionally used, typically ‘DARWINISTS’ ASSUMED THAT MOST DNA WAS FUNCTIONAL. Basically they thought natural selection regulated everything, and if something wasn’t performing a useful function, it would be eliminated by natural selection. This described a common position up until the 1960s.

    “Junk DNA” only started to become a popular idea because of reasons like (a) data started coming in indicating that genomes were way bigger than they had to be to specify genes and regulation, (b) genome sizes were ridiculously variable between similar organisms, and (c) the development of neutral theory, which explained how “junk” could accumulate without causing major harm to organisms. NEUTRAL THEORY IS NON-DARWINIAN. NEUTRAL THEORY IS ALSO NOW EXTREMELY WELL ACCEPTED IN EVOLUTIONARY BIOLOGY. SO ITS BIZARRE FOR YOU TO GO AROUND SAYING “DARWINISTS” PREDICTED JUNK DNA.

    You, like most ID/creationists, have your own special definition of “Darwinist”, which is, basically, anyone you don’t like, or anyone who is against ID. Your misunderstanding of the definition of “Darwinist”, and the epic mistakes this leads to (you getting the position of “Darwinists” on Junk DNA exactly backwards) is what Larry is complaining about. Why is it so hard for you to get it?

  3. 3
    Andre says:

    Nick_Matzke

    Lets test your claim

    You, like most ID/creationists, have your own special definition of “Darwinist”, which is, basically, anyone you don’t like, or anyone who is against ID. Your misunderstanding of the definition of “Darwinist”, and the epic mistakes this leads to (you getting the position of “Darwinists” on Junk DNA exactly backwards) is what Larry is complaining about. Why is it so hard for you to get it?

    Is Richard Dawkins a Darwinist? Based on the article I linked he most certainly is.

    http://www.theguardian.com/sci.....n.dawkins1

    So if he is a Darwinist and he said;

    “It stretches even their creative ingenuity to make a convincing reason why an intelligent designer should have created a pseudogene — a gene that does absolutely nothing and gives every appearance of being a superannuated version of a gene that used to do something — unless he was deliberately setting out to fool us…

    Leaving pseudogenes aside, it is a remarkable fact that the greater part (95 percent in the case of humans) of the genome might as well not be there, for all the difference it makes.”

    Then your opening statmenet is obviously false

    What you aren’t getting is that, in the way the term ‘Darwinists’ was traditionally used, typically ‘DARWINISTS’ ASSUMED THAT MOST DNA WAS FUNCTIONAL. Basically they thought natural selection regulated everything, and if something wasn’t performing a useful function, it would be eliminated by natural selection. This described a common position up until the 1960s.

    Why? Because that comment was made by Dawkins in 2009. So clearly you are confused.

  4. 4
    bFast says:

    NM_UD, “NEUTRAL THEORY IS NON-DARWINIAN”
    Wrong! How many times to I have to explain to yous guys that neutral theory answers the question of what happens to mutations that are selectively neutral (or near neutral in the case of near neutral theory). Now it is true that most mutations are selectively neutral, but all mutations must submit to the test of Darwinian selection, therefore neutral theory is a subset of neo-Darwinian theory. To pretend otherwise is just semantics.

    We do understand, you and yours try to pretend that we don’t.

    NM_UD, ““Junk DNA” only started to become a popular idea because of reasons like …” You are correct, and this is known by me, and surely by BA. However, when the junk theory became known, it began to sail rather quickly. It did so because it was a natural prediction of neo-Darwinan theory. The fact that it was not predicted by the theorists earlier only shows that their understanding of the theory lacked richness, not that the theory didn’t predict “junk”. Ie, the theory properly predicted “junk” prior to the theorists figuring out that it did so.

    NM_UD, “You, like most ID/creationists, have your own special definition of “Darwinist”, which is, basically, anyone you don’t like, or anyone who is against ID.”

    No! No! We use the term Darwinist, or neo-Darwinist to indicate all those whose theory falls within the scope of RM+NS. (Where Random is read as random with respect to fitness, or as Dr. MacNeill said, “non-foresighted”.) The term properly extends to any mechanism which ostensibly developed via RM+NS.

  5. 5
    Andre says:

    Then in why evolution is True, Professor Emeritus Jerry Coyne says

    When a trait is no longer used, or becomes reduced, the genes that make it don’t instantly disappear from the genome: evolution stops their action by inactivating them, not snipping them out of the DNA. From this we can make a prediction. We expect to find, in the genomes of many species, silenced, or ‘dead,’ genes: genes that once were useful but are no longer intact or expressed. In other words, there should be vestigial genes…Our genome—and that of other species—are truly well populated graveyards of dead genes.

  6. 6
    Andre says:

    Is Jerry Coyne a darwinist?

    In Biology online he said

    Still, these advances amount to refinements of Darwinism rather than its Kuhnian overthrow. Evolutionary biology hasn’t suffered the equivalent of quantum mechanics. But some biologists, chafing in their Darwinian straitjacket, periodically announce new worldviews that, they claim, will overturn our view of evolution, or at least force its drastic revision. During my career I have heard this said about punctuated equilibrium, molecular drive, the idea of symbiosis as an evolutionary force, evo-devo, and the notion that evolution is driven by the self-organization of molecules. Some of these ideas are worthwhile, others simply silly; but none do more than add a room or two to the Darwinian manse. Often declared dead, Darwinism still refuses to lie down. So by all means let’s retain the term. It is less of a jawbreaker than “modern evolutionary biology,” and has not, as was feared, misled people into thinking that our field has remained static since 1859. What better honorific than “Darwinism” to fête the greatest biologist in history?

  7. 7
    kairosfocus says:

    BA,

    It seems that the rhetorical, dismissive talking points go and come in a cycle of waves.

    Just now, I noted to DK as follows:

    _______

    >> . . . do you seriously expect us to believe something as close to hand as a Wiki article is not understood as to fundamental claims from Darwin forward?

    In effect:

    chance, non-foresighted, blind watchmaker variation [someone once posted 47 engines of variation, and this includes neutral drifting etc] [= CV] +

    differential reproductive success of varieties in environments [= DRS, aka “natural selection”] +

    other filtering out of variations [= OF] –>

    extinction of less successful varieties [= XLSV] –>

    incremental descent with modification [= IDWM] –>

    similarly incremental branching tree evolution [= BTE] –>

    tree of life pattern of life forms [= TOL]

    Or,

    CV + DRS + OF –> XLSV –> IDWM –> BTE –> TOL

    So summed up it is soon evident that the vaunted natural selection is in fact only an after the fact description of the LOSS of varieties and associated information. It is therefore not a SOURCE of information, it is a lossy filter.

    The only actually posited source is chance variation, which is simply not up to the job of accounting for the FSCO/I required to give dozens of main body plans requirinf 10 – 100+ mn bits of information here on earth in a window of 600 MY or less. In the case of humans vs chimps, on the 98% similarity claim, one needs to account for 60 mn bases or 120 mn bits of crucially diverse information in 6 – 10 mn years with pop bases probably of order 10,000 and generation times 5 – 20 years.

    Worse, this does not address the FSCO/I in the root of the tree, in which context existing reproduction is not to be assumed. Indeed, the von Neumann kinematic self replicator coded info using complex system has to be accounted for.

    VC is right to highlight that an actual, empirically warranted comprehensive macro level theory of body plan origin by evolution that — without imposition of ideological a priori evolutionary materialism — is testable and tested, does not exist.

    Johnson’s remark is apt:

    For scientific materialists the materialism comes first; the science comes thereafter. [Emphasis original] We might more accurately term them “materialists employing science.” And if materialism is true, then some materialistic theory of evolution has to be true simply as a matter of logical deduction, regardless of the evidence.

    [–> notice, the power of an undisclosed, question-begging, controlling assumption . . . often put up as if it were a mere reasonable methodological constraint; emphasis added. Let us note how Rational Wiki, so-called, presents it:

    “Methodological naturalism is the label for the required assumption of philosophical naturalism when working with the scientific method. Methodological naturalists limit their scientific research to the study of natural causes, because any attempts to define causal relationships with the supernatural are never fruitful, and result in the creation of scientific “dead ends” and God of the gaps-type hypotheses.”

    Of course, this ideological imposition on science that subverts it from freely seeking the empirically, observationally anchored truth about our world pivots on the deception of side-stepping the obvious fact since Plato in The Laws Bk X, that there is a second, readily empirically testable and observable alternative to “natural vs [the suspect] supernatural.” Namely, blind chance and/or mechanical necessity [= the natural] vs the ART-ificial, the latter acting by evident intelligently directed configuration. [Cf Plantinga’s reply here and here.]

    And as for the god of the gaps canard, the issue is, inference to best explanation across competing live option candidates. If chance and necessity is a candidate, so is intelligence acting by art through design. And if the latter is twisted into a caricature god of the gaps strawman, then locked out, huge questions are being oh so conveniently begged.]

    That theory will necessarily be at least roughly like neo-Darwinism, in that it will have to involve some combination of random changes and law-like processes capable of producing complicated organisms that (in Dawkins’ words) “give the appearance of having been designed for a purpose.”

    . . . . The debate about creation and evolution is not deadlocked . . . Biblical literalism is not the issue. The issue is whether materialism and rationality are the same thing. Darwinism is based on an a priori commitment to materialism, not on a philosophically neutral assessment of the evidence. Separate the philosophy from the science, and the proud tower collapses. [Emphasis added.] [The Unraveling of Scientific Materialism, First Things, 77 (Nov. 1997), pp. 22 – 25.]

    It is time for a serious re-think.>>
    _________

    KF

  8. 8
    bornagain says:

    as to Moran’s claim,

    “nobody predicted junk DNA, certainly not Darwinists.”

    Dawkins, 2009: on “junkDNA”

    “Junk DNA is just what a Darwinist would expect,”

    Dawkins, 2012: on non-junkDNA (after ENCODE)…

    “”junk DNA” isn’t junk at all but is instead “exactly what a Darwinist would hope for,”
    http://www.evolutionnews.org/2.....64521.html

    Further notes:

    Jonathan Wells on his book, The Myth of Junk DNA – yes, it is a Darwinist myth and he nails it as such – March 2011
    Excerpt: Some people revise history by claiming that no mainstream biologists ever regarded non-protein-coding DNA as “junk.”
    This claim is easily disproved: Francis Crick and Leslie Orgel published an article in Nature in 1980 (284: 604-607) arguing that such DNA “is little better than junk,” and “it would be folly in such cases to hunt obsessively” for functions in it. Since then, Brown University biologist Kenneth R. Miller, Oxford University biologist Richard Dawkins, University of Chicago biologist Jerry A. Coyne, and University of California–Irvine biologist John C. Avise have all argued that most of our DNA is junk, and that this provides evidence for Darwinian evolution and against intelligent design. National Institutes of Health director Francis Collins argued similarly in his widely read 2006 book The Language of God.
    It is true that some biologists (such as Thomas Cavalier-Smith and Gabriel Dover) have long been skeptical of “junk DNA” claims, but probably a majority of biologists since 1980 have gone along with the myth. The revisionists are misinformed (or misinforming).
    http://www.uncommondescent.com.....more-18154

    Susumu Ohno, 1972,
    Ford Doolittle, 1980,
    Francis Crick & Leslie Orgel, 1980,
    Carl Sagan, 1992
    Kenneth Miller, 1994
    Sydney Brenner, 1998
    Francis Collins, 2006
    Michael Shermer, 2006
    PZ Myers, 2008
    Richard Dawkins, 1979, 1998, 2009
    John Avise, 2010
    Dan Graur et al, 2012, 2013
    Don Prothero, 2013
    T. Ryan Gregory, & Alexander Palazzo, 2014
    http://notascientist.d512.com/...../junk-dna/

    A Short History Of The Junk DNA Argument Of Darwinists

    Haldane’s Dilemma
    Excerpt: Haldane was the first to recognize there was a cost to selection which limited what it realistically could be expected to do. He did not fully realize that his thinking would create major problems for evolutionary theory. He calculated that in man it would take 6 million years to fix just 1,000 mutations (assuming 20 years per generation).,,, Man and chimp differ by at least 150 million nucleotides representing at least 40 million hypothetical mutations (Britten, 2002). So if man evolved from a chimp-like creature, then during that process there were at least 20 million mutations fixed within the human lineage (40 million divided by 2), yet natural selection could only have selected for 1,000 of those. All the rest would have had to been fixed by random drift – creating millions of nearly-neutral deleterious mutations. This would not just have made us inferior to our chimp-like ancestors – it surely would have killed us. Since Haldane’s dilemma there have been a number of efforts to sweep the problem under the rug, but the problem is still exactly the same. ReMine (1993, 2005) has extensively reviewed the problem, and has analyzed it using an entirely different mathematical formulation – but has obtained identical results.
    John Sanford PhD. – “Genetic Entropy and The Mystery of the Genome” – pg. 159-160

    Kimura’s Quandary
    Excerpt: Kimura realized that Haldane was correct,,, He developed his neutral theory in response to this overwhelming evolutionary problem. Paradoxically, his theory led him to believe that most mutations are unselectable, and therefore,,, most ‘evolution’ must be independent of selection! Because he was totally committed to the primary axiom (neo-Darwinism), Kimura apparently never considered his cost arguments could most rationally be used to argue against the Axiom’s (neo-Darwinism’s) very validity.
    John Sanford PhD. – “Genetic Entropy and The Mystery of the Genome” – pg. 161 – 162

    Kimura (1968) developed the idea of “Neutral Evolution”. If “Haldane’s Dilemma” is correct, the majority of DNA must be non-functional.
    – Sanford

    (i.e. neutral theory is actually the result of a theoretical failure of Darwinism within mathematics!)

    A graph featuring ‘Kimura’s Distribution’ being ‘properly used’ is shown in the following video:

    Evolution vs Genetic Entropy – Andy McIntosh – video – 59:27 minute mark
    https://youtu.be/-GLJE4FbHnk?t=3567

    At the 2:45 minute mark of the following video, the mathematical roots of the junk DNA argument, that is still used by many Darwinists today, can be traced through Haldane, Kimura, and Ohno’s work in the late 1950’s, 60’s through the early 70’s:

    What Is The Genome? It’s Not Junk! – Dr. Robert Carter – video – (Notes in video description)
    http://www.metacafe.com/w/8905583

    Carter: Why Evolutionists Need Junk DNA – Robert W. Carter – 2009
    Excerpt: Junk DNA is not just a label that was tacked on to some DNA that seemed to have no function, but it is something that is required by evolutionary theory. Mathematically, there is too much variation, too much DNA to mutate, and too few generations in which to get it all done. This was the essence of Haldane’s work. Without junk DNA, evolutionary theory cannot currently explain how everything works mathematically. Think about it; in the evolutionary model there have only been 3-6 million years since humans and chimps diverged. With average human generation times of 20-30 years, this gives them only 100,000 to 300,000 generations to fix the millions of mutations that separate humans and chimps. This includes at least 35 million single letter differences, over 90 million base pairs of non-shared DNA, nearly 700 extra genes in humans (about 6% not shared with chimpanzees), and tens of thousands of chromosomal rearrangements. Also, the chimp genome is about 13% larger than that of humans, but mostly due to the heterochromatin that caps the chromosome telomeres. All this has to happen in a very short amount of evolutionary time. They don’t have enough time, even after discounting the functionality of over 95% of the genome–but their position becomes grave if junk DNA turns out to be functional. Every new function found for junk DNA makes the evolutionists’ case that much more difficult.
    Robert W. Carter – biologist

    Susumu Ohno, a leader in the field of genetics and evolutionary biology, explained in 1972 in an early study of non-coding DNA that, “they are the remains of nature’s experiments which failed. The earth is strewn with fossil remains of extinct species; is it a wonder that our genome too is filled with the remains of extinct genes?”

    “The chance of acquiring a new function by unrestricted accumulation of mutations, however, should be as small as that of an isolated population emerging triumphant as a new species. Degeneracy is the more likely fate. The creation of every new gene must have been accompanied by many other redundant copies joining the ranks of silent DNA base sequences, and these silent DNA base sequence may now be serving the useful but negative function of spacing those which have succeeded. Triumphs as well as failures of nature’s past experiments appear to be contained in our genome.”
    [From, “So much ‘junk’ DNA in our Genome”, Susumu Ohno, 1972]

    Sternberg traces how the junk DNA argument developed through the mid 1970’s to the early 80’s and beyond in the following article:

    How The Junk DNA Hypothesis Has Changed Since 1980 – Richard Sternberg – October 8, 2009
    Excerpt: Two papers appeared back to back in the journal Nature in 1980: “Selfish Genes, the Phenotype Paradigm and Genome Evolution” by W. Ford Doolittle and Carmen Sapienza and “Selfish DNA: The Ultimate Parasite” by Leslie Orgel and Francis Crick. These laid the framework for thinking about nonprotein-coding regions of chromosomes, judging from how they are cited. What these authors effectively did was advance Dawkins’s 1976 selfish gene idea in such a way that all the genomic DNA evidence available up to that time could be accounted for by a plausible scenario. The thesis presented in both articles is that the only specific function of the vast bulk of “nonspecific” sequences, especially repetitive elements such as transposons, is to replicate themselves — this is the consequence of natural selection operating within genomes, beneath the radar of the cell. These junk sequences, it was postulated, can duplicate and disperse throughout chromosomes because they have little or no effect on the phenotype, save for the occasional mutation that results from their mobility.
    http://www.evolutionnews.org/2.....26421.html

    Biologists are racking their brains trying to think what useful task this apparently surplus DNA is doing. But from the point of view of the selfish genes themselves, there is no paradox. The true “purpose” of DNA is to survive, no more and no less. The simplest way to explain the surplus DNA is to suppose that it is a parasite, or at best a harmless but useless passenger, hitching a ride in the survival machines created by the other DNA.
    …. “creationists…might spend some earnest time speculating on why the Creator should bother to litter genomes with untranslated pseudogenes and junk tandem repeat DNA.”
    Richard Dawkins – Selfish Gene (mid 1970’s)

    Selfish DNA: the ultimate parasite. Orgel LE, Crick FH. – 1980
    The DNA of higher organisms usually falls into two classes, one specific and the other comparatively nonspecific. It seems plausible that most of the latter originates by the spreading of sequences which had little or no effect on the phenotype.
    http://www.ncbi.nlm.nih.gov/pubmed/7366731

    Dr. Wells also gives some historical background:

    Why All the Fuss Over Some Junk? – Jonathan Wells – September 25, 2012
    Excerpt: Some historical context might help. After James Watson and Francis Crick discovered the molecular structure of DNA in 1953, Crick announced that they had found “the secret of life,” a popular formulation of which became “DNA makes RNA makes protein makes us.” But biologists discovered that about 98% of our DNA does not code for protein, and in 1972 Susumu Ohno and David Comings independently used the term “junk” to refer to non-protein-coding DNA (though neither man excluded the possibility that some of it might turn out to be functional).
    Why didn’t biologists simply call non-protein-coding sequences “DNA of unknown function” rather than “junk DNA?” For some, it was because “junk DNA” seemed more suited to the defense of Darwinism and survival of the fittest. In 1976, Richard Dawkins wrote in The Selfish Gene that “the true ‘purpose’ of DNA is to survive, no more and no less. The simplest way to explain the surplus [i.e., non-protein-coding] DNA is to suppose that it is a parasite, or at best a harmless but useless passenger, hitching a ride in the survival machines created by the other DNA.”
    In 1980, W. Ford Doolittle and Carmen Sapienza wrote in Nature (284:601) that many organisms contain “DNAs whose only ‘function’ is survival within genomes,” and that “the search for other explanations may prove, if not intellectually sterile, ultimately futile.” In the same issue of Nature (284:604), Leslie Orgel and Francis Crick wrote that “much DNA in higher organisms is little better than junk,” and its accumulation in the course of evolution “can be compared to the spread of a not-too-harmful parasite within its host.” Since it is unlikely that such DNA has a function, Orgel and Crick concluded, “it would be folly in such cases to hunt obsessively for one.”
    Two biologists then wrote to Nature (285:617,618) expressing their disagreement. Thomas Cavalier-Smith considered it “premature” to dismiss non-protein-coding DNA as junk, and Gabriel Dover wrote that “we should not abandon all hope of arriving at an understanding of the manner in which some sequences might affect the biology of organisms in completely novel and somewhat unconventional ways.” Cavalier-Smith and Dover were not criticizing evolutionary theory; they were merely questioning the claim that non-protein-coding DNA is non-functional.
    After the rise of intelligent design (ID) in the 1990s, “junk DNA” became a favorite weapon against ID in the hands of some Darwinists, including Richard Dawkins and the four bloggers mentioned above. According to ID, it is possible to infer from evidence in nature that some features of the world, including some features of living things, are explained better by an intelligent cause than by unguided natural processes. The Darwinists’ argument was that an intelligent designer would not have filled our genomes with so much junk, but that it could have accumulated as an accidental by-product of unguided evolution. In 2004, Dawkins wrote in A Devil’s Chaplain that much of our genome “consists of multiple copies of junk, ‘tandem repeats,’ and other nonsense which may be useful for forensic detectives but which doesn’t seem to be used in the body itself.” Dawkins suggested that creationists (among whom he included ID advocates) “might spend some earnest time speculating on why the Creator should bother to litter genomes with untranslated pseudogenes and junk tandem repeat DNA.”
    Dawkins continued to rely on junk DNA in his 2009 book The Greatest Show on Earth: The Evidence for Evolution. “It is a remarkable fact,” he wrote, “that the greater part (95 per cent in the case of humans) of the genome might as well not be there, for all the difference it makes.” In particular, pseudogenes “are genes that once did something useful but have now been sidelined and are never transcribed or translated.” Dawkins concluded: “What pseudogenes are useful for is embarrassing creationists. It stretches even their creative ingenuity to make up a convincing reason why an intelligent designer should have created a pseudogene… unless he was deliberately setting out to fool us.”
    http://www.evolutionnews.org/2.....64721.html

    In 1994, the authoritative textbook, Molecular Biology of the Cell, co-authored by National Academy of Sciences president Bruce Alberts, suggested (incorrectly!) that introns are “largely genetic ‘junk'”: Unlike the sequence of an exon, the exact nucleotide sequence of an intron seems to be unimportant. Thus introns have accumulated mutations rapidly during evolution, and it is often possible to alter most of an intron’s nucleotide sequence without greatly affecting gene function. This has led to the suggestion that intron sequences have no function at all and are largely genetic “junk”.
    Soon thereafter, the 1995 edition of Voet & Voet’s Biochemistry textbook explained that “a possibility that must be seriously entertained is that much repetitive DNA serves no useful purpose whatever for its host. Rather, it is selfish or junk DNA, a molecular parasite that, over many generations, has disseminated itself throughout the genome…”

    Will Darwinists try to Rewrite the History of Junk-DNA?
    Excerpt: In 1996, leading origin of life theorist Christian de Duve wrote: “The simplest way to explain the surplus DNA is to suppose that it is a parasite or at best a harmless but useless passenger, hitching a ride in the survival machines created by the other DNA.” (Richard Dawkins makes similar pronouncements that DNA is junk in an article after 1998)
    per ENV

    Another leading biologist, Sydney Brenner argued in a biology journal in 1998 that:

    “The excess DNA in our genomes is junk, and it is there because it is harmless, as well as being useless, and because the molecular processes generating extra DNA outpace those getting rid of it.”

    A decade before ENCODE, John Mattick said the junk DNA argument “may well go down as one of the biggest mistakes in the history of molecular biology.”

    “I think this will come to be a classic story of orthodoxy derailing objective analysis of the facts, in this case for a quarter of a century,” Mattick says. “The failure to recognize the full implications of this—particularly the possibility that the intervening noncoding sequences may be transmitting parallel information in the form of RNA molecules—may well go down as one of the biggest mistakes in the history of molecular biology.”
    (John S. Mattick Scientific American (November, 2003)

  9. 9
    Virgil Cain says:

    Earth to NickMatzke, Both you and larry Moran constantly and consistently misrepresent ID. You also both oversell evolutionism. You have steadfastly refused to say how it was determined that gene duplications are genetic accidents, errors and mistakes.

    Also in what way is neutral theory non-Darwinian seeing that darwin talked about drift in “On the Origins of Species…”? Darwin just didn’t see it as a creative force and rightly so.

  10. 10

    NickMatzke_UD: “typically ‘DARWINISTS’ ASSUMED THAT MOST DNA WAS FUNCTIONAL.”

    What a liar. Darwinists have always, since Darwin, predicted that randomness and evolution would produce a lot of dysfunctional crap. And Darwinists still continuously gleefully point out crappy inefficiency, vestigal uselessness, and junk dna.

    Point out any influential Darwinist who says that “most DNA is functional.” Even in the present day, you cannot point to a single one, otherwise you would have quoted them saying it.

  11. 11
    Barry Arrington says:

    Nick @ 2:

    For your statements to be true, Jerry Coyne would have to not be a Darwinist. Jerry Coyne is a Darwinist. Therefore, your statements is false.

    It really is as simple as that.

  12. 12
    vjtorley says:

    Richard Dawkins on junk DNA:

    https://www.youtube.com/watch?v=_bjKH43pRB0

    At 0:44, discussing the ENCODE results, he declares:

    …Whereas we thought that only a minority of the genome was actually doing something – namely, the minority that actually codes for protein – now we find that actually the majority of it is doing something. What it’s doing i calling into action the protein-coding genes.

    Later (at 1:43) Dawkins says that this result “is exactly what a Darwinist would hope for.” But the video clips show him referring to genes that are “vestigial relics,” during talks he gave only two years earlier (in 2011). How many genes are we talking about? A lot, it seems: he refers to “massive, massive, massive quantities of evidence,” in the genomes of “every species of creature that’s ever been looked at.” Finally, Dawkins exults that the vestigial genes belonging to various kinds of creatures yield the same family tree as the functional genes.

    Selective video editing, you say? Think again. The following quotes from Dawkins are taken from an ENV post (September 20, 2012) by David Klinghoffer, titled, “In Debate, Britain’s Chief Rabbi Tweaks Richard Dawkins with the Myth of “Junk DNA.” Here’s Richard Dawkins in 2009:

    It stretches even their creative ingenuity to make a convincing reason why an intelligent designer should have created a pseudogene — a gene that does absolutely nothing and gives every appearance of being a superannuated version of a gene that used to do something — unless he was deliberately setting out to fool us…
    Leaving pseudogenes aside, it is a remarkable fact that the greater part (95 percent in the case of humans) of the genome might as well not be there, for all the difference it makes.

    And here he is in 2012, after ENCODE announced its results:

    I have noticed that there are some creationists who are jumping on [the ENCODE results] because they think that’s awkward for Darwinism. Quite the contrary it’s exactly what a Darwinist would hope for, to find usefulness in the living world….

    Whereas we thought that only a minority of the genome was doing something, namely that minority which actually codes for protein, and now we find that actually the majority of it is doing something. What it’s doing is calling into action the protein-coding genes. So you can think of the protein-coding genes as being sort of the toolbox of subroutines which is pretty much common to all mammals — mice and men have the same number, roughly speaking, of protein-coding genes and that’s always been a bit of a blow to self-esteem of humanity. But the point is that that was just the subroutines that are called into being; the program that’s calling them into action is the rest [of the genome] which had previously been written off as junk.

    It seems to me that Darwinism is a highly malleable theory.

  13. 13
    Barry Arrington says:

    BA77 provides overwhelming evidence @ 8. Thank you sir.

  14. 14
    Jack Jones says:

    Larry Moran is pathetic. He deletes comments of the opposition that show him up but allows his minions who contribute nothing to the discussion, to attack people for not accepting Moran’s claims as pearls of wisdom that must remain unchallenged.

  15. 15
    Mung says:

    Sorry, but Larry is right on this one.

    The theory did not predict junk DNA, but when junk DNA was discovered, it was exactly what the theory would have predicted.

  16. 16
    Virgil Cain says:

    The “theory” doesn’t predict anything beyond change when change is good and stasis when staying the same is good.

  17. 17
    Zachriel says:

    bornagain: Dawkins, 2009: on “junkDNA” “Junk DNA is just what a Darwinist would expect,”

    Do you have a primary citation for this quote?

  18. 18
    Jack Jones says:

    Virgil said “The “theory” doesn’t predict anything beyond change when change is good and stasis when staying the same is good.”

    Evolution is more of a philosophy that accommodates everything. It is philosophical dogma.

  19. 19
    bFast says:

    Zachriel, I found the source of this quote:

    http://www.evolutionnews.org/2.....64521.html reporting on BBC debate between Dawkins and Jonathan Sacks.

    The evolutionnews.org article states:

    Dawkins goes on:
    Leaving pseudogenes aside, it is a remarkable fact that the greater part (95 percent in the case of humans) of the genome might as well not be there, for all the difference it makes.

    evolutionnews.org then editorializes:

    Junk DNA is just what a Darwinist would expect, in other words.

    While your challenge is correct, Dawkins didn’t appear to say what was attributed to him, the dent you make in the argument is miniscule.

  20. 20
    bornagain says:

    Sorry Zach, I quoted Klinghoffer paraphrasing Dawkins. My mistake. Here is the cite.

    Back in 2009, in The Greatest Show on Earth (pp. 332-333), he was presenting the supposed junkiness of the vast majority of the genome as an assured scientific reality and one that is, in the specific case of “pseudogenes,” “useful for. . . embarrassing creationists.”

    It stretches even their creative ingenuity to make a convincing reason why an intelligent designer should have created a pseudogene — a gene that does absolutely nothing and gives every appearance of being a superannuated version of a gene that used to do something — unless he was deliberately setting out to fool us.

    Dawkins goes on:

    Leaving pseudogenes aside, it is a remarkable fact that the greater part (95 percent in the case of humans) of the genome might as well not be there, for all the difference it makes.

    That was in 2009, just three years ago. Back then, the purported fact that 95 percent of the human genome “might as well not be there” was an embarrassment “for creationists,” whom in typical Darwinian fashion Dawkins conveniently conflates with intelligent-design advocates. Junk DNA is just what a Darwinist would expect, in other words.

    Cut to 2012, and now the evident fact that “junk DNA” isn’t junk at all but is instead vital for life has become “exactly what a Darwinist would hope for,” namely, “to find usefulness in the living world.” That is, heads you lose, tails I win. A wonderful man like Rabbi Sacks would probably have to shed his courtliness for a moment to properly call out Dawkins on this blatant, unacknowledged and suspiciously convenient self-contradiction. Ah well, as we knew already, being a Darwinist means never having to say “I was wrong.”
    http://www.evolutionnews.org/2.....64521.html

    Lest anyone think Dawkins, the author of ‘The Selfish Gene”, did not actually expect junk DNA in that quote, here a few more quotes from Dawkins which people can look up for themselves’

    Richard Dawkins
    The Selfish Gene, page 45
    Oxford University Press, 1976
    “A large fraction of DNA is never translated into protein… Biologists are racking their brains trying to think what useful task this apparently surplus DNA is doing. But from the point of view of the selfish genes themselves, there is no paradox. The true “purpose” of DNA is to survive, no more and no less. The simplest way to explain the surplus DNA is to suppose that it is a parasite, or at best a harmless but useless passenger.”

    Richard Dawkins
    The Information Challenge
    Australian Skeptics, 1998
    In a response to a creationist challenge regarding evolution producing information, Richard Dawkins wrote:
    ” Can we measure the information capacity of that portion of the genome which is actually used? We can at least estimate it. In the case of the human genome it is about 2%?—?considerably less than the proportion of my hard disc that I have ever used since I bought it… The true information content is what’s left when the redundancy has been compressed out of the message, by the theoretical equivalent of Stuffit.”

    and again the 2009 reference

    Richard Dawkins
    The Greatest Show on Earth: The Evidence for Evolution, pages 332-333
    Free Press, 2009
    “What pseudogenes are useful for is embarrassing creationists… Leaving pseudogenes aside, it is a remarkable fact that the greater part (95 per cent in the case of humans) of the genome might as well not be there, for all the difference it makes. The neutral theory applies even to many of the genes in the remaining 5 per cent–the genes that are read and used…. None of this is to downgrade the all-important tip of the iceberg–the minority of mutations that are not neutral.”
    http://notascientist.d512.com/.....na/sources

    i.e. Dawkins was wrong!

  21. 21
    Zachriel says:

    bFast: While your challenge is correct, Dawkins didn’t appear to say what was attributed to him, the dent you make in the argument is miniscule.

    The reason it’s relevant is because the view was ascribed to a “Darwinist”, which is not in the original quote.

  22. 22
    Zachriel says:

    bornagain: Junk DNA is just what a Darwinist would expect, in other words.

    No, not in other words. Darwinism is a word with several related meanings, but most often refers to someone who thinks that evolution proceeds primarily by natural selection. A Darwinist would generally accept some vestigialism in the genome, but many would probably think that it gets weeded out over time, rather than accumulating.

  23. 23
    bornagain says:

    So now, apparently to draw attention away from the elephant in the living room, Zach claims Dawkins is not a Darwinist?

    Incredible!

    Yes folks, this is absurdity dealt with day in and day out from Darwinists.

    Matthew 23:24
    You blind guides! You strain out a gnat but swallow a camel.

  24. 24
    Zachriel says:

    bornagain: Zach claims Dawkins is not a Darwinist?

    Didn’t say that. Dawkins takes a gene-centric view of Darwinism.

  25. 25
    Andre says:

    Zachriel

    Watch the debate and hear with your own ears

  26. 26
    bornagain says:

    Zachriel, whatever splitting hairs view you want to adopt on Darwinism, it is still wrong.

    Primarily the reason Darwinism, and all its current many headed snake versions, are wrong is because the reductive materialism upon which Darwinism rests is now empirically shown to be wrong.

    The empirical falsification of Darwinism is as such. Darwinian presuppositions hold that all the information, (and even consciousness), in life is merely an ‘emergent’ property of a material basis, but it is now found that beyond space and time, non-local, ‘quantum information’, which is not reducible to a material basis, is in molecular biology.

    First, it is important to learn that ‘non-local’, beyond space and time, quantum entanglement (A. Aspect, A. Zeilinger, etc..) can be used as a ‘quantum information channel’,,,

    Quantum Entanglement and Information
    Quantum entanglement is a physical resource, like energy, associated with the peculiar nonclassical correlations that are possible between separated quantum systems. Entanglement can be measured, transformed, and purified. A pair of quantum systems in an entangled state can be used as a quantum information channel to perform computational and cryptographic tasks that are impossible for classical systems. The general study of the information-processing capabilities of quantum systems is the subject of quantum information theory.
    http://plato.stanford.edu/entries/qt-entangle/

    And this non-local quantum information is now found in molecular biology on a massive scale, in every DNA and Protein molecule

    Classical and Quantum Information in DNA – Elisabeth Rieper – video (Longitudinal Quantum Information along the entire length of DNA discussed at the 19:30 minute mark; at 24:00 minute mark Dr Rieper remarks that practically the whole DNA molecule can be viewed as quantum information with classical information embedded within it)
    https://youtu.be/2nqHOnVTxJE?t=1176

    Classical and Quantum Information Channels in Protein Chain – Dj. Koruga, A. Tomi?, Z. Ratkaj, L. Matija – 2006
    Abstract: Investigation of the properties of peptide plane in protein chain from both classical and quantum approach is presented. We calculated interatomic force constants for peptide plane and hydrogen bonds between peptide planes in protein chain. On the basis of force constants, displacements of each atom in peptide plane, and time of action we found that the value of the peptide plane action is close to the Planck constant. This indicates that peptide plane from the energy viewpoint possesses synergetic classical/quantum properties. Consideration of peptide planes in protein chain from information viewpoint also shows that protein chain possesses classical and quantum properties. So, it appears that protein chain behaves as a triple dual system: (1) structural – amino acids and peptide planes, (2) energy – classical and quantum state, and (3) information – classical and quantum coding. Based on experimental facts of protein chain, we proposed from the structure-energy-information viewpoint its synergetic code system.
    http://www.scientific.net/MSF.518.491

    Quantum coherent-like state observed in a biological protein for the first time – October 13, 2015
    Excerpt: If you take certain atoms and make them almost as cold as they possibly can be, the atoms will fuse into a collective low-energy quantum state called a Bose-Einstein condensate. In 1968 physicist Herbert Fröhlich predicted that a similar process at a much higher temperature could concentrate all of the vibrational energy in a biological protein into its lowest-frequency vibrational mode. Now scientists in Sweden and Germany have the first experimental evidence of such so-called Fröhlich condensation (in proteins).,,,
    The real-world support for Fröhlich’s theory (for proteins) took so long to obtain because of the technical challenges of the experiment, Katona said.
    http://phys.org/news/2015-10-q.....otein.html

    Of related note, like entanglement, quantum coherence is a ‘non-local’, beyond space and time, effect:

    Coherence and nonlocality
    Usually quantum nonlocality is discussed in terms of correlated multiparticle systems such as those discussed by John Bell in his famous 1964 theorem and then later clarified by GHZ, David Mermin and others.
    But more striking and significant is the qualitative nonlocal phenomena associated with coherent states,,,,
    In fact, theoretically these two kinds of nonlocality have precisely the same basis: the unmeasured singlet state uncovered by EPR is a coherent ‘pure state’ despite its spacial extension, and when the parts are realized in a measurement (a la Bell) this coherence is harvested or cashed in.
    Whereas the “EPR” connections are ephemeral and fragile, some forms of nonlocal coherence are robust.
    http://www.nonlocal.com/hbar/n.....rence.html

    And although Naturalists have proposed various, far fetched, naturalistic scenarios to try to get around the Theistic implications of quantum non-locality, none of the ‘far fetched’ naturalistic solutions, in themselves, are compatible with the reductive materialism that undergirds neo-Darwinian thought.

    “[while a number of philosophical ideas] may be logically consistent with present quantum mechanics, …materialism is not.”
    Eugene Wigner
    Quantum Physics Debunks Materialism – video playlist
    https://www.youtube.com/watch?list=PL1mr9ZTZb3TViAqtowpvZy5PZpn-MoSK_&v=4C5pq7W5yRM

    Why Quantum Theory Does Not Support Materialism By Bruce L Gordon, Ph.D
    Excerpt: The underlying problem is this: there are correlations in nature that require a causal explanation but for which no physical explanation is in principle possible. Furthermore, the nonlocalizability of field quanta entails that these entities, whatever they are, fail the criterion of material individuality. So, paradoxically and ironically, the most fundamental constituents and relations of the material world cannot, in principle, be understood in terms of material substances. Since there must be some explanation for these things, the correct explanation will have to be one which is non-physical – and this is plainly incompatible with any and all varieties of materialism.
    http://www.4truth.net/fourtrut.....8589952939

    Thus, as far as empirical science itself is concerned, Neo-Darwinism is falsified in its claim that the information in molecular biology is ‘emergent’ from a reductive material basis.

    If Darwinism were a real science, instead of a religion for atheists, this finding, (as well as many other findings in the past), should have relegated Darwinism to the dustbin of disproven scientific theories

    Snake bites its own body after head is severed – video
    http://www.metro.us/news/video.....Dy6SDAQ4w/

    Top 10 Most Famous Scientific Theories (That Turned out to be Wrong)
    http://www.toptenz.net/top-10-.....-wrong.php

  27. 27
    Carpathian says:

    Barry,

    The irony….

    Jack Jones:

    Larry Moran is pathetic. He deletes comments of the opposition that show him up but allows his minions who contribute nothing to the discussion, to attack people for not accepting Moran’s claims as pearls of wisdom that must remain unchallenged.

  28. 28
    bFast says:

    Zachriel, “Darwinism … often refers to someone who thinks that evolution proceeds primarily by natural selection.”

    Zachriel, “Darwinism is a word with several related meanings.”

    Yes, Zachriel, the latter is correct. Darwinism is a word with several related meanings. You know right well which meaning is used by the supporters of this site. For you to disrespect that position is just equivocation, obfuscation.

    From dictionary of bfast:

    Darwinism:
    a: Those who propose that non-foresighted variation + natural selection, along with its products, can explain all of life.
    b: Someone who thinks that evolution proceeds primarily by natural selection.

    For the purposes of productive dialog, please use definition a above for all general discussion purposes on this blog. Then productivity may happen, rather than a bunch of equivocation.

  29. 29
    Virgil Cain says:

    Darwin only said that the appearance of design was to be attributed to natural selection. He wrote about random drift but he knew it isn’t a creative mechanism. So yes, drift is part of Darwinism and neo-Darwinism and has been since 1859.

  30. 30
    Virgil Cain says:

    Zachriel:

    A Darwinist would generally accept some vestigialism in the genome, but many would probably think that it gets weeded out over time, rather than accumulating.

    A Darwinist can accept as much junk DNA as is allowed, ie isn’t fatal.

  31. 31
    Zachriel says:

    bFast: Darwinism:
    a: Those who propose that non-foresighted variation + natural selection, along with its products, can explain all of life.

    As evolutionary theory only concerns the diversification of life and not its origin, that would not be a suitable definition.

    Why do IDers insist up on the term Darwinism, which only leads to confusion?

  32. 32
    bFast says:

    Zachriel, “As evolutionary theory only concerns the diversification of life and not its origin, that would not be a suitable definition.”

    RRRRR, Error!

    While it is true that OOL is the purview of a different branch of science, those who hold to the Darwinian model hold to the assumption that RV+NS explains the origin of life as well as its development.

    Zachriel, “Why do IDers insist up on the term Darwinism, which only leads to confusion?”

    A term is needed. I have asked frequently for another term. Your side has offered such loaded responses as “evolutionary scientists”. A bit wordy, but mostly a very loaded term.

    When we write Darwinist, you know exactly what we mean. Therefore the confusion is in your determination to declare it confusing, not with our term.

    Lastly: ” “Darwinism” is a compact, four-syllable term for “modern evolutionary theory,” Jerry Coyne. If its good enough for the great guru Coyne, it is good enough for me.

  33. 33
    Zachriel says:

    bFast: While it is true that OOL is the purview of a different branch of science, those who hold to the Darwinian model hold to the assumption that RV+NS explains the origin of life as well as its development.

    That’s not necessarily the case. Someone can support evolutionary theory without making such a claim about the origin of life.

    bFast: A term is needed.

    Philosophical naturalists may be what you are looking for.

    bFast: “Darwinism” is a compact, four-syllable term for “modern evolutionary theory,” Jerry Coyne.

    Unfortunately, it leads to confusion. Furthermore, it is not the same as the definition you just provided.

    bFast: When we write Darwinist, you know exactly what we mean.

    No. It varies too much between people. Moran reserves it for those who think most of evolution is explained by natural selection, which is how it is mostly used in biology. Bornagain uses it to refer to “reductive materialism”. You claim it refers to all aspects of life including its origin. Coyne argues it should refer to modern evolutionary theory.

  34. 34
    Larry Moran says:

    The quotation from Francis Collins is irrelevant. What he’s saying is that IF there is junk DNA THEN mutations will accumulate in that stretch of DNA.

    The reason they will occur and become fixed is because they are neutral with respect to selection so they will be fixed by random genetic drift.

    Collins says that this is predicted by Darwin’s theory but this is clearly false since Darwin never described such a situation. It’s also false according to the glossary entry on “Darwinism” since there’s no mention there of neutral alleles or random genetic drift.

    Besides, Francis Collins reverted to the traditional “Darwinist” view of complex genomes over a decade ago. He now believes that most of the human genome is functional and that we shouldn’t use the term “junk DNA.”

    Classical pseudogenes are a minor exception. They are junk but they make up less than 1% of the genome if you only count exons. They just don’t count for very much in the junk DNA debate. Even encode acknowledges them.

  35. 35
    bFast says:

    “Moran reserves … ”
    I don’t include Moran in the camp of “we”. Moran’s position is infantile.

    Bornagain uses it to refer to “reductive materialism”
    How does “reductive materialism” differ from my definition?

    “Coyne argues it should refer to modern evolutionary theory.” And how does that differ to my definition with the exception of scope? (One could argue that by including OOL, I have stepped beyond the scope of MET.) Oh, and, is there any evidence anywhere that Coyne holds any view of OOL other than the definition I use when referring to Darwinism?

  36. 36
    Larry Moran says:

    The quotation from Jerry Coyne is about pseudogenes. Again, this is a minor part of the junk DNA debate. Jerry is saying that when a gene is rendered inactive by mutation it is not immediately purged from the genome. This seems pretty obvious—I don’t know anyone who thinks otherwise.

    I think we can all understand why new pseudogenes don’t disappear right away but the question is why do they persist for millions of years?

    That’s a problem for Darwinists because carrying that extra DNA is costly and should be selected against by natural selection. They persist because they are effectively neutral in populations with a small population size like mammals. They are invisible to natural selection and will only be eliminated by random genetic drift—a low probability event. They are purged from bacterial genomes because bacterial species have huge population sizes.

    This concept is not covered in the glossary entry on “Darwinism” so I assume that it’s something the ID version of Darwinism can’t explain.

    Of course, this has nothing to do with the real debate over junk DNA because pseudogenes are a minor player in that debate.

    One thing puzzles me, though. Barry Arrington said …

    This statement [by Elizabeth Liddle] is breathtakingly false. Let us take just one example. For years Darwinists touted “junk DNA” as not just any evidence but powerful, practically irrefutable evidence for the Darwinian hypothesis. ID proponents disagreed and argued that the evidence would ultimately demonstrate function.

    Not only did both hypotheses make testable predictions, the Darwinist prediction turned out to be false and the ID prediction turned out to be confirmed.

    If the discussion is going to focus on pseudogenes then what is Barry’s stance?

    Does he believe that there’s no such thing as pseudogenes and all of them has been shown to be functional according to ID predictions? That’s the implication from what he said to Elizabeth Liddle and the fact that he concentrates on pseudogenes in this post.

    So, is it fair to say that ID proponents reject the idea of pseudogenes and claim that they all have a function? Is that in conflict with the kind of Darwinism described in the glossary or is it compatible with a strong emphasis on the role of natural selection?

    If pseudogenes are really pseudogenes, do ID proponents admit that at least some parts of the genome are junk? What part of the glossary entry on “Darwinism” predicts such a thing?

  37. 37
    Virgil Cain says:

    Zachriel:

    Someone can support evolutionary theory without making such a claim about the origin of life.

    How? If the OoL was designed then organisms were designed to evolve. Only if the OoL was due to physicochemical processes would we say that is how evolution proceeds.

  38. 38
    Virgil Cain says:

    Pseudogenes- if evolution proceeds by breaking things and keeping them around then I am sure everyone can understand the problem.

  39. 39
    Larry Moran says:

    Barry Arrington says,

    No, I did not say that Darwinism predicted junk DNA. I said Darwinists said the theory predicted junk DNA, and as I demonstrated above, they did. And no, I did not say that junk DNA is strong evidence for the Darwinian hypothesis. Those same Darwinists made that claim. I said exactly the opposite, i.e., that ID proponents disagreed.

    This seems like unnecessary quibbling to me. True, you said that “Darwinists” predicted junk DNA not that “Darwinism” predicted junk DNA.

    Presumably you have in mind some sort of Venn diagram where there’s an incomplete overlap between “Darwinists” and proponents of “Darwinism.”

    When I said …

    Barry Arrington says that Darwinism predicted junk DNA and that junk DNA is strong evidence of the Darwinian hypothesis.

    I did not mean to imply that YOU predicted junk DNA and YOU think that junk DNA is strong evidence of Darwinism.

    Nor did I mean to imply that anyone but “Darwinists” make such a claim, according to YOUR view of the field. I’m not sure what your problem is. Do you think that Darwinists are wrong and Darwinism DOESN’T predict the existence of junk DNA? Do you think that the “Darwinists” are wrong and junk DNA is NOT strong evidence of Darwinism?

    Because if that’s what you think then we agree. Junk DNA refutes Darwinism.

    Problem is, no true “Darwinist” will disagree.

    It’s all very confusing. Can you answer my questions?

  40. 40
    Virgil Cain says:

    Larry Moran doesn’t understand darwinism:

    That’s a problem for Darwinists because carrying that extra DNA is costly…

    What is that cost, Larry? Please show your work.

    Thanks to the ever efficient intelligent design of ATP synthase my bet is the cost is low and unnoticed. But that is because the alleged junk is actually used for something and the cost accounted for.

    …and should be selected against by natural selection.

    Whatever is good enough gets to survive and reproduce, Larry. Natural selection isn’t an anal-retentive perfectionist. It doesn’t optimize. It eliminates and due to cooperation what gets eliminated is often those that have no chance at all.

    Natural selection is just the only mechanism posited to explain the appearance of design in living organisms. Drift boils down to luck and there is only so much luck science can accept in an explanation.

  41. 41
    Virgil Cain says:

    Zachriel:

    Why do IDers insist up on the term Darwinism, which only leads to confusion?

    Why do evos insist up on the term evolutionary theory, which only leads to confusion (because there isn’t any such thing)?

  42. 42
    Jack Jones says:

    “Why do evos insist up on the term evolutionary theory, which only leads to confusion (because there isn’t any such thing)?”

    Spot on Mr Cain.

    When Evolutionists can’t agree on what the theory is, then it is ridiculous for evolutionists to use the term “evolutionary theory”

  43. 43
    Larry Moran says:

    Virgil Cain asks,

    What is that cost, Larry? Please show your work.

    The cost of a new gene

    Lynch and Marinov show that the cost is significant in bacterial populations but insignificant in the populations of large multicellular species.

    It’s perfectly understandable according to modern evolutionary theory that includes population genetics, Neutral Theory, and random genetic drift.

    How do you account for the purging of short non-functional DNA sequences in bacteria but not in mammals? Can you show me where that fits into your understanding of Darwinism as outlined in the glossary?

    Please try hard to answer the question.

  44. 44
    Virgil Cain says:

    Larry Moran:

    Lynch and Marinov show that the cost is significant in bacterial populations but insignificant in the populations of large multicellular species.

    So it isn’t costly.

    It’s perfectly understandable according to modern evolutionary theory that includes population genetics, Neutral Theory, and random genetic drift.

    Can you please reference this modern evolutionary theory so we can read what it says?

    How do you account for the purging of short non-functional DNA sequences in bacteria but not in mammals?

    Bacteria don’t need extra DNA to fill for the DNA coils. They don’t need extra memory for the added programming required to run eukaryotes. They are streamlined for fast reproduction. Spiegelman’s monster applies.

    Mammals have introns and exons. This is for alternative splicing. They have their DNA wrapped into coils and the extra DNA is used for spacing along those coils.

  45. 45
    Virgil Cain says:

    My apologies to John Lennon:

    Imagine all mutations
    It’s easy if you try
    With no limitations
    They gave us you & I
    Imagine all mutations occurring every day

    Imagine there’s no mutant
    It isn’t hard to do
    Exact clones to kill or die for
    And equilibrium too
    Imagine all that stasis clogging up the tree

    You may say it’s evolution
    When it is all said and done
    Natural selection is just impotent
    And drift gets nothing done

    (work in progress)

  46. 46
    bornagain says:

    It is interesting to note that Darwinists have been postulating, theorizing, and hypothesizing, galore for years as to how information just might arise by unguided material processes, but in all this postulating, theorizing, and hypothesizing galore, by Darwinists you will never find an empirical demonstration of unguided material processes ever actually creating any information.

    In other words, all the postulating, theorizing, and hypothesizing, galore by Darwinists is all smoke and mirrors to cover up the embarrassing fact that material processes cannot create information.

    Just one observed instance of unguided material processes creating non-trivial functional information would falsify ID.

    The Origin of Information: How to Solve It – Perry Marshall
    Where did the information in DNA come from? This is one of the most important and valuable questions in the history of science. Cosmic Fingerprints has issued a challenge to the scientific community:
    “Show an example of Information that doesn’t come from a mind. All you need is one.”
    “Information” is defined as digital communication between an encoder and a decoder, using agreed upon symbols. To date, no one has shown an example of a naturally occurring encoding / decoding system, i.e. one that has demonstrably come into existence without a designer.
    A private equity investment group is offering a technology prize for this discovery. We will financially reward and publicize the first person who can solve this;,,, To solve this problem is far more than an object of abstract religious or philosophical discussion. It would demonstrate a mechanism for producing coding systems, thus opening up new channels of scientific discovery. Such a find would have sweeping implications for Artificial Intelligence research.
    http://cosmicfingerprints.com/solve/

    The Law of Physicodynamic Incompleteness – David L. Abel
    Excerpt: “If decision-node programming selections are made randomly or by law rather than with purposeful intent, no non-trivial (sophisticated) function will spontaneously arise.”
    If only one exception to this null hypothesis were published, the hypothesis would be falsified. Falsification would require an experiment devoid of behind-the-scenes steering. Any artificial selection hidden in the experimental design would disqualify the experimental falsification. After ten years of continual republication of the null hypothesis with appeals for falsification, no falsification has been provided.
    The time has come to extend this null hypothesis into a formal scientific prediction:
    “No non trivial algorithmic/computational utility will ever arise from chance and/or necessity alone.”
    https://www.academia.edu/Documents/in/The_Law_of_Physicodynamic_Incompleteness

    Whereas ID can easily be falsified by experimental observation, Darwinists, on the other hand, have no such falsification criteria:

    “The National Academy of Sciences has objected that intelligent design is not falsifiable, and I think that’s just the opposite of the truth. Intelligent design is very open to falsification. I claim, for example, that the bacterial flagellum could not be produced by natural selection; it needed to be deliberately intelligently designed. Well, all a scientist has to do to prove me wrong is to take a bacterium without a flagellum, or knock out the genes for the flagellum in a bacterium, go into his lab and grow that bug for a long time and see if it produces anything resembling a flagellum. If that happened, intelligent design, as I understand it, would be knocked out of the water. I certainly don’t expect it to happen, but it’s easily falsified by a series of such experiments.
    Now let’s turn that around and ask, How do we falsify the contention that natural selection produced the bacterial flagellum? If that same scientist went into the lab and knocked out the bacterial flagellum genes, grew the bacterium for a long time, and nothing much happened, well, he’d say maybe we didn’t start with the right bacterium, maybe we didn’t wait long enough, maybe we need a bigger population, and it would be very much more difficult to falsify the Darwinian hypothesis.
    I think the very opposite is true. I think intelligent design is easily testable, easily falsifiable, although it has not been falsified, and Darwinism is very resistant to being falsified. They can always claim something was not right.”
    – Dr Michael Behe

    “Now, one can’t have it both ways. One can’t say both that ID is unfalsifiable (or untestable) and that there is evidence against it. Either it is unfalsifiable and floats serenely beyond experimental reproach, or it can be criticized on the basis of our observations and is therefore testable. The fact that critical reviewers advance scientific arguments against ID (whether successfully or not) shows that intelligent design is indeed falsifiable.

    In fact, my argument for intelligent design is open to direct experimental rebuttal. Here is a thought experiment that makes the point clear. In Darwin’s Black Box (Behe 1996) I claimed that the bacterial flagellum was irreducibly complex and so required deliberate intelligent design. The flip side of this claim is that the flagellum can’t be produced by natural selection acting on random mutation, or any other unintelligent process. To falsify such a claim, a scientist could go into the laboratory, place a bacterial species lacking a flagellum under some selective pressure (for mobility, say), grow it for ten thousand generations, and see if a flagellum–or any equally complex system–was produced. If that happened, my claims would be neatly disproven.”
    Michael Behe
    – clipped from: Confirmation of intelligent design predictions
    http://reasonandscience.heaven.....redictions

    Without such a rigid falsification criteria, Darwinian evolution, sans Popper, does not even really qualify as a science:

    “In so far as a scientific statement speaks about reality, it must be falsifiable; and in so far as it is not falsifiable, it does not speak about reality.”
    Karl Popper – The Two Fundamental Problems of the Theory of Knowledge (2014 edition), Routledge

    “On the other hand, I disagree that Darwin’s theory is as `solid as any explanation in science.; Disagree? I regard the claim as preposterous. Quantum electrodynamics is accurate to thirteen or so decimal places; so, too, general relativity. A leaf trembling in the wrong way would suffice to shatter either theory. What can Darwinian theory offer in comparison?”
    – Berlinski, D., “A Scientific Scandal?: David Berlinski & Critics,” Commentary, July 8, 2003

    Also of note, despite all the mathematical theorizing that Moran prides himself in, the fact of the matter is that Darwinian evolution has no rigid mathematical basis to test against:

    Active Information in Metabiology – Winston Ewert, William A. Dembski, Robert J. Marks II – 2013
    Except page 9: Chaitin states [3], “For many years I have thought that it is a mathematical scandal that we do not have proof that Darwinian evolution works.” In fact, mathematics has consistently demonstrated that undirected Darwinian evolution does not work.,,
    Consistent with the laws of conservation of information, natural selection can only work using the guidance of active information, which can be provided only by a designer.
    http://bio-complexity.org/ojs/.....O-C.2013.4

    Chaitin is quoted at 10:00 minute mark of following video in regards to Darwinism lack of a mathematical proof – Dr. Marks also comments on the honesty of Chaitin in personally admitting that his long sought after mathematical proof for Darwinian evolution failed to deliver the goods.

    On Algorithmic Specified Complexity by Robert J. Marks II – video
    https://www.youtube.com/watch?v=No3LZmPcwyg&feature=player_detailpage#t=600

    WHAT SCIENTIFIC IDEA IS READY FOR RETIREMENT? Evolution is True – Roger Highfield – January 2014
    Excerpt:,,, Whatever the case, those universal truths—’laws’—that physicists and chemists all rely upon appear relatively absent from biology.
    Little seems to have changed from a decade ago when the late and great John Maynard Smith wrote a chapter on evolutionary game theory for a book on the most powerful equations of science: his contribution did not include a single equation.
    http://www.edge.org/response-detail/25468

    “It is our contention that if ‘random’ is given a serious and crucial interpretation from a probabilistic point of view, the randomness postulate is highly implausible and that an adequate scientific theory of evolution must await the discovery and elucidation of new natural laws—physical, physico-chemical, and biological.”
    Murray Eden, “Inadequacies of Neo-Darwinian Evolution as a Scientific Theory,” Mathematical Challenges to the Neo-Darwinian Interpretation of Evolution, editors Paul S. Moorhead and Martin M. Kaplan, June 1967, p. 109.

    Pauli’s ideas on mind and matter in the context of contemporary science – Harald Atmanspacher
    Excerpt: “In discussions with biologists I met large difficulties when they apply the concept of ‘natural selection’ in a rather wide field, without being able to estimate the probability of the occurrence in a empirically given time of just those events, which have been important for the biological evolution. Treating the empirical time scale of the evolution theoretically as infinity they have then an easy game, apparently to avoid the concept of purposesiveness. While they pretend to stay in this way completely ‘scientific’ and ‘rational,’ they become actually very irrational, particularly because they use the word ‘chance’, not any longer combined with estimations of a mathematically defined probability, in its application to very rare single events more or less synonymous with the old word ‘miracle.’”
    Wolfgang Pauli (pp. 27-28)
    http://www.igpp.de/english/tda/pdf/paulijcs8.pdf

    ID suffers no such embarrassment as Darwinian evolution suffers for having no rigid mathematical basis within science

    Evolutionary Computing: The Invisible Hand of Intelligence – June 17, 2015
    Excerpt: William Dembski and Robert Marks have shown that no evolutionary algorithm is superior to blind search — unless information is added from an intelligent cause, which means it is not, in the Darwinian sense, an evolutionary algorithm after all. This mathematically proven law, based on the accepted No Free Lunch Theorems, seems to be lost on the champions of evolutionary computing. Researchers keep confusing an evolutionary algorithm (a form of artificial selection) with “natural evolution.” ,,,
    Marks and Dembski account for the invisible hand required in evolutionary computing. The Lab’s website states, “The principal theme of the lab’s research is teasing apart the respective roles of internally generated and externally applied information in the performance of evolutionary systems.” So yes, systems can evolve, but when they appear to solve a problem (such as generating complex specified information or reaching a sufficiently narrow predefined target), intelligence can be shown to be active. Any internally generated information is conserved or degraded by the law of Conservation of Information.,,,
    What Marks and Dembski prove is as scientifically valid and relevant as Gödel’s Incompleteness Theorem in mathematics. You can’t prove a system of mathematics from within the system, and you can’t derive an information-rich pattern from within the pattern.,,,
    http://www.evolutionnews.org/2.....96931.html

  47. 47
    Daniel King says:

    He [Darwin] wrote about random drift but he knew it isn’t a creative mechanism. So yes, drift is part of Darwinism and neo-Darwinism and has been since 1859.

    You made that up.

    Prove it.

  48. 48
    Virgil Cain says:

    Darwin, 1859

  49. 49
    Larry Moran says:

    Virgil Cain says,

    Mammals have introns and exons. This is for alternative splicing.

    How do you know this? Did some “Darwinists” tell you about alternative splicing? Why do you believe them when you don’t believe anything else they say?

    What if it turns out that only a small percentage of mammalian genes are alternatively spliced, do you have another theory?

    Alternative Splicing and Why IDiots Don’t Understand How Science Works

    How much intron sequence is needed for alternative splicing? I have estimated that it’s no more than 80 bp. That only accounts for a tiny percentage of the human genome.

    Why Do the IDiots Have So Much Trouble Understanding Introns?

  50. 50
    Larry Moran says:

    Virgil Cain says,

    Darwin only said that the appearance of design was to be attributed to natural selection. He wrote about random drift but he knew it isn’t a creative mechanism. So yes, drift is part of Darwinism and neo-Darwinism and has been since 1859.

    If it’s important, maybe you should ask Barry Arrington to put it into the glossary entry on “Darwinism” so everyone will know that this is what Darwin said?

    As for drift being creative, have you read …

    Constructive Neutral Evolution (CNE)

    Do you understand it? Is it part of your “Darwinism” theory?

    I’m not asking to to accept or believe in something like constructive neutral evolution but you should at least know about it before you say what you think evolutionary biologists believe. It’s simply not true to say that natural selection is the only possible, unguided, way to create the appearance of design and complexity.

  51. 51
    bornagain says:

    constructive neutral evolution

    Michael Behe on the theory of constructive neutral evolution – February 2012
    Excerpt: I don’t mean to be unkind, but I think that the idea seems reasonable only to the extent that it is vague and undeveloped; when examined critically it quickly loses plausibility. The first thing to note about the paper is that it contains absolutely no calculations to support the feasibility of the model. This is inexcusable.
    – Michael Behe
    http://www.uncommondescent.com.....evolution/

  52. 52
    bornagain says:

    Alternative splicing is another evidence that falsifies Darwinian evolution.

    First off, codes must be implemented top down. It is physically impossible to evolve a code from the bottom up. All of our empirical evidence confirms this fact. In fact, so solid is this scientific fact that Perry Marshall has organized a 3 million dollar prize for the first person who can prove to the contrary that codes can possibly evolve in a bottom up Darwinian fashion without a mind.
    In other words, it ain’t going to happen. A technical way of understanding this fact is ‘Shannon channel capacity’

    “Because of Shannon channel capacity that previous (first) codon alphabet had to be at least as complex as the current codon alphabet (DNA code), otherwise transferring the information from the simpler alphabet into the current alphabet would have been mathematically impossible”
    Donald E. Johnson – Bioinformatics: The Information in Life

    But an easier way of understanding why a code will never evolve in a gradual bottom up Darwinian fashion is elucidated by Dawkins himself:

    Venter vs. Dawkins on the Tree of Life – and Another Dawkins Whopper – March 2011
    Excerpt:,,, But first, let’s look at the reason Dawkins gives for why the code must be universal:
    “The reason is interesting. Any mutation in the genetic code itself (as opposed to mutations in the genes that it encodes) would have an instantly catastrophic effect, not just in one place but throughout the whole organism. If any word in the 64-word dictionary changed its meaning, so that it came to specify a different amino acid, just about every protein in the body would instantaneously change, probably in many places along its length. Unlike an ordinary mutation…this would spell disaster.” (2009, p. 409-10)
    OK. Keep Dawkins’ claim of universality in mind, along with his argument for why the code must be universal, and then go here (linked site listing 23 variants of the genetic code).
    Simple counting question: does “one or two” equal 23? That’s the number of known variant genetic codes compiled by the National Center for Biotechnology Information. By any measure, Dawkins is off by an order of magnitude, times a factor of two.
    http://www.evolutionnews.org/2.....44681.html

    The bottom line is that if any code is ‘randomly changed’ in part, it throws a huge monkey wrench into the code and will be ‘instantly catastrophic’, to use Richard Dawkins most appropriate term, to the species thus rendering gradual change to the code impossible.
    In other words, the entire code must be implemented ‘top down’!
    Please note, this is not randomly changing sequences within the code that we are talking about, this is talking about making changes to a code itself.

    The reason I bring this non-evolvability of codes up is because of alternative splicing codes.
    Namely, alternative splicing codes are found to be ‘species-specific’.

    First off, there is an alternative splicing code:

    Deciphering the splicing code – May 2010
    Excerpt: Here we describe the assembly of a ‘splicing code’, which uses combinations of hundreds of RNA features to predict tissue-dependent changes in alternative splicing for thousands of exons. The code determines new classes of splicing patterns, identifies distinct regulatory programs in different tissues, and identifies mutation-verified regulatory sequences.,,,
    http://www.nature.com/nature/j.....09000.html

    Breakthrough: Second Genetic Code Revealed – May 2010
    Excerpt: The paper is a triumph of information science that sounds reminiscent of the days of the World War II codebreakers. Their methods included algebra, geometry, probability theory, vector calculus, information theory, code optimization, and other advanced methods. One thing they had no need of was evolutionary theory,,,
    http://crev.info/content/break.....e_revealed

    Researchers Crack ‘Splicing Code,’ Solve a Mystery Underlying Biological Complexity – May 2010
    Excerpt: “Understanding a complex biological system is like understanding a complex electronic circuit. Our team ‘reverse-engineered’ the splicing code using large-scale experimental data generated by the group,”
    http://www.sciencedaily.com/re.....133252.htm

    Secondly, alternative splicing is astonishing:

    Researchers Crack ‘Splicing Code,’ Solve a Mystery Underlying Biological Complexity
    Excerpt: “For example, three neurexin genes can generate over 3,000 genetic messages that help control the wiring of the brain,” says Frey. “Previously, researchers couldn’t predict how the genetic messages would be rearranged, or spliced, within a living cell,” Frey said. “The splicing code that we discovered has been successfully used to predict how thousands of genetic messages are rearranged differently in many different tissues.
    http://www.sciencedaily.com/re.....133252.htm

    Design In DNA – Alternative Splicing, Duons, and Dual coding genes – video (5:05 minute mark)
    http://www.youtube.com/watch?v=Bm67oXKtH3s#t=305

    The Extreme Complexity Of Genes – Dr. Raymond G. Bohlin – video
    http://www.metacafe.com/watch/8593991/

    Time to Redefine the Concept of a Gene? – Sept. 10, 2012
    Excerpt: As detailed in my second post on alternative splicing, there is one human gene that codes for 576 different proteins, and there is one fruit fly gene that codes for 38,016 different proteins!
    While the fact that a single gene can code for so many proteins is truly astounding, we didn’t really know how prevalent alternative splicing is. Are there only a few genes that participate in it, or do most genes engage in it? The ENCODE data presented in reference 2 indicates that at least 75% of all genes participate in alternative splicing. They also indicate that the number of different proteins each gene makes varies significantly, with most genes producing somewhere between 2 and 25.
    Based on these results, it seems clear that the RNA transcripts are the real carriers of genetic information. This is why some members of the ENCODE team are arguing that an RNA transcript, not a gene, should be considered the fundamental unit of inheritance.
    http://networkedblogs.com/BYdo8

    Landscape of transcription in human cells – Sept. 6, 2012
    Excerpt: Here we report evidence that three-quarters of the human genome is capable of being transcribed, as well as observations about the range and levels of expression, localization, processing fates, regulatory regions and modifications of almost all currently annotated and thousands of previously unannotated RNAs. These observations, taken together, prompt a redefinition of the concept of a gene.,,,
    Isoform expression by a gene does not follow a minimalistic expression strategy, resulting in a tendency for genes to express many isoforms simultaneously, with a plateau at about 10–12 expressed isoforms per gene per cell line.
    http://www.nature.com/nature/j.....11233.html

  53. 53
    bornagain says:

    Thirdly, the alternative splicing code is ‘species-specific’

    Canadian Team Develops Alternative Splicing Code from Mouse Tissue Data
    Excerpt: “Our method takes as an input a collection of exons and surrounding intron sequences and data profiling how those exons are spliced in different tissues,” Frey and his co-authors wrote. “The method assembles a code that can predict how a transcript will be spliced in different tissues.”
    http://www.genomeweb.com/infor.....issue-data

    And yet these supposed ‘junk intron sequences’, that Darwinists use to ignore (as Moran is desperately trying to do now), that were used to decipher the splicing code of different tissue types in an organism, are found to be exceptionally different between chimpanzees and Humans:

    Modern origin of numerous alternatively spliced human introns from tandem arrays – 2006
    Excerpt: A comparison with orthologous regions in mouse and chimpanzee suggests a young age for the human introns with the most-similar boundaries. Finally, we show that these human introns are alternatively spliced with exceptionally high frequency.
    http://www.pnas.org/content/104/3/882.full

    Characterization and potential functional significance of human-chimpanzee large INDEL variation – October 2011
    Excerpt:,,, we categorized human-chimpanzee INDEL (Insertion, Deletion) variation mapping in or around genes and determined whether this variation is significantly correlated with previously determined differences in gene expression.
    Results: Extensive, large INDEL (Insertion, Deletion) variation exists between the human and chimpanzee genomes. This variation is primarily attributable to retrotransposon insertions within the human lineage. There is a significant correlation between differences in gene expression and large human-chimpanzee INDEL variation mapping in genes or in proximity to them.
    http://www.mobilednajournal.co.....3-2-13.pdf

    Jonathan Wells comments on the fallacious ‘Darwinian Logic’, within the preceding paper, that falsely tried to attribute the major differences that were found in INDEL variation to unguided Darwinian processes:

    Darwinian Logic: The Latest on Chimp and Human DNA – Jonathan Wells – October 2011
    Excerpt: Protein-coding regions of DNA in chimps and humans are remarkably similar — 98%, by many estimates — and this similarity has been used as evidence that the two species are descended from a common ancestor. Yet chimps and humans are very different anatomically and behaviorally, and even thirty years ago some biologists were speculating that those differences might be due to non-protein-coding regions, which make up about 98% of chimp and human DNA. (In other words, the 98% similarity refers to only 2% of the genome.) Now a research team headed by John F. McDonald at Georgia Tech has published evidence that large segments of non-protein-coding DNA differ significantly between chimps and humans,,,, If the striking similarities in protein-coding DNA point to the common ancestry of chimps and humans, why don’t dissimilarities in the much more abundant non-protein-coding DNA point to their separate origins?
    http://www.evolutionnews.org/2.....52291.html

    This following, more recent, paper also found that Alternative Splicing patterns are ‘species specific’:

    Evolution by Splicing – Comparing gene transcripts from different species reveals surprising splicing diversity. – Ruth Williams – December 20, 2012
    Excerpt: A major question in vertebrate evolutionary biology is “how do physical and behavioral differences arise if we have a very similar set of genes to that of the mouse, chicken, or frog?”,,,
    A commonly discussed mechanism was variable levels of gene expression, but both Blencowe and Chris Burge,,, found that gene expression is relatively conserved among species.
    On the other hand, the papers show that most alternative splicing events differ widely between even closely related species. “The alternative splicing patterns are very different even between humans and chimpanzees,” said Blencowe.,,,
    http://www.the-scientist.com/?.....plicing%2F

    Gene Regulation Differences Between Humans, Chimpanzees Very Complex – Oct. 17, 2013
    Excerpt: Although humans and chimpanzees share,, similar genomes, previous studies have shown that the species evolved major differences in mRNA (messenger RNA) expression levels.,,,
    http://www.sciencedaily.com/re.....144632.htm

    ,,,Alternative splicing,,, may contribute to species differences – December 21, 2012
    Excerpt: After analyzing vast amounts of genetic data, the researchers found that the same genes are expressed in the same tissue types, such as liver or heart, across mammalian species. However, alternative splicing patterns—which determine the segments of those genes included or excluded—vary from species to species.,,,
    The results from the alternative splicing pattern comparison were very different. Instead of clustering by tissue, the patterns clustered mostly by species. “Different tissues from the cow look more like the other cow tissues, in terms of splicing, than they do like the corresponding tissue in mouse or rat or rhesus,” Burge says. Because splicing patterns are more specific to each species, it appears that splicing may contribute preferentially to differences between those species, Burge says,,,
    Excerpt of Abstract: To assess tissue-specific transcriptome variation across mammals, we sequenced complementary DNA from nine tissues from four mammals and one bird in biological triplicate, at unprecedented depth. We find that while tissue-specific gene expression programs are largely conserved, alternative splicing is well conserved in only a subset of tissues and is frequently lineage-specific. Thousands of previously unknown, lineage-specific, and conserved alternative exons were identified;
    http://phys.org/news/2012-12-e.....wires.html

    Of related interest: The position and organization of genes on the chromosome is not arbitrary

    Refereed scientific article on DNA argues for irreducible complexity – October 2, 2013
    Excerpt: This paper published online this summer is a true mind-blower showing the irreducible organizational complexity (author’s description) of DNA analog and digital information, that genes are not arbitrarily positioned on the chromosome etc.,,
    ,,,First, the digital information of individual genes (semantics) is dependent on the the intergenic regions (as we know) which is like analog information (syntax). Both types of information are co-dependent and self-referential but you can’t get syntax from semantics. As the authors state, “thus the holistic approach assumes self-referentiality (completeness of the contained information and full consistency of the different codes) as an irreducible organizational complexity of the genetic regulation system of any cell”. In short, the linear DNA sequence contains both types of information. Second, the paper links local DNA structure, to domains, to the overall chromosome configuration as a dynamic system keying off the metabolic signals of the cell. This implies that the position and organization of genes on the chromosome is not arbitrary,,,
    http://www.christianscientific.....complexity

  54. 54
    Virgil Cain says:

    Larry Moran:

    How do you know this? Did some “Darwinists” tell you about alternative splicing? Why do you believe them when you don’t believe anything else they say?

    Sorry but I only accept what there is evidence for.

    What if it turns out that only a small percentage of mammalian genes are alternatively spliced, do you have another theory?

    All I know is natural selection can’t account for it. Drift can’t account for it. Neutral theory can’t account for it and creative neutral theory can’t account for it.

    Did you read your own article on creative neutral theory? It is all contingent serendipity! Is that really your idea of science?

    But I digress, I don’t know the number of different proteins in the human body. The number of genes is 20,000(ish) but I have read varying numbers on the protein side. And not knowing enough about the design of the genome I couldn’t say why only a small fraction would utilize alternative splicing.

    But if you think that natural selection and drift- creative or not- can produce a spliceosome it is up to you to come up with some way to test that claim.

    Thank you for telling me that there are scientists who actually think that contingent serendipity/constructive neutral evolution, is a viable mechanism for creating adaptations. Please let Futuyma know as all his textbooks proudly proclaim that NS is the only known mechanism to produce adaptations. Unfortunately we don’t even have evidence that it can. It is all done by proclamation- “Natural selection is the only mechanism capable of producing adaptations. Here are some adaptations produced by natural selection.”

    Now he has to add contingent serendipity.

  55. 55
    Virgil Cain says:

    Daniel pufferfish @ 47-

    Variations neither useful nor injurious would not be affected by natural selection, and would be left either a fluctuating element, as perhaps we see in certain polymorphic species, or would ultimately become fixed, owing to the nature of the organism and the nature of the conditions.- On the Origins of Species sixth edition chapter 4, end of paragraph 1

    Variations neither useful nor injurious would not be affected by natural selection, and would be left a fluctuating element, as perhaps we see in the species called polymorphic.- first edition

  56. 56
    Andre says:

    Ha! So genetic drift is Darwinian. Larry Moran is a Darwinist and that is a fact. Does the avarage Darwinist know what facts are?

  57. 57
    goodusername says:

    Ha! So genetic drift is Darwinian.

    What does that even mean? How are you defining “Darwinian”? Do you equate Darwinian with “evolutionary”? If not, is there any evolutionary change that you wouldn’t say is Darwinian?

  58. 58
    Andre says:

    Goodusername

    Non-Darwinian evolution;

    Lamarckism
    Orthogenesis
    Deterministic Evolution

    There are examples of non-Darwinian evolution, I personally agree with Lamarckism or better known today as Epigenetics.

    http://www.sciencedaily.com/re.....141448.htm

  59. 59
    bFast says:

    Andre, Lamarican evolution surely has some validity. However, it is a mechanism that is presumably developed via the magic of RM+NS. I know of nobody who seriously sees lamaricanism to be the fundamental driving force of evolution.

    Orthogenesis and Deterministic Evolution are bosom buddies. The are variants of the front loading hypothesis. They are telic, presumed to be “designed to evolve”.

    goodusername, “Do you equate Darwinian with “evolutionary”?” No. Evolution is change over time. As such we all have evolutionary views. Darwinian is “via purely natural processes”, specifically the processes of random (non-foresighted) variation + natural selection. RM+NS are presumed to be capable of developing sub-processes including human genetic engineering. (All of human engineering actually.)

  60. 60
    goodusername says:

    Andre,

    Well, that answer makes your comment #56 even more puzzling.

    Darwin wrote quite a bit defending the inheritance of acquired characteristics and “use and disuse inheritance”.
    And he even developed the pangenesis hypothesis as a mechanism for how such inheritance could work.

    Off the top of my head, I can’t think of any reference to drift in Origin, but there is a statement in Descent that I believe could be interpreted as backing the idea of drift, although I think most see the idea of drift as originating in the 1930s.

    But somehow drift is Darwinian and Lamarckism isn’t?

    Darwin believed that he came up with a mechanism for evolution (selection), but also believed there were many other mechanisms, including inheritance of acquired characteristics, and possibly drift, but didn’t see the former as part of his mechanism, and almost certainly wouldn’t see the latter as part of his mechanism (after all, it’s the opposite of selection!)

  61. 61

    @bornagain wrote: “It is physically impossible to evolve a code from the bottom up.”

    Coding is simply a form of mathematics, and mathematics is ordered by the zero. Fundamentally mathematics is universal, and code is also universal.

    In mathematical theory the 1 is derived by rewriting the 0. So then you have 2 different symbols, which have the same information content, which means they have a boolean relationship. Then you can do the binary 0101010111110 computercode.

    Variations in codes, it doesn’t apply to the basic structure of the code. In every code 5-2=3

    So to say the structure of the code follows from the ordering by 0, which is a law of the universe. The basic structure is neither evolved, nor chosen top down. One cannot intelligently decide the rules in 5-2 = 3 nor evolve the rules in 5-2=3 by selection.

  62. 62
    Zachriel says:

    bFast: I don’t include Moran in the camp of “we”. Moran’s position is infantile.

    Moran’s position is conventional. In biology, darwinian evolution generally refers to evolution by natural selection.

    bFast: Bornagain uses it to refer to “reductive materialism” How does “reductive materialism” differ from my definition?

    Because reductive materialism is a philosophical position, that everything can be reduced to material mechanisms, while your definition only refers to life. So someone might believe the Big Bang is beyond natural explanation, but “propose that non-foresighted variation + natural selection, along with its products, can explain all of life.”

    When talking about evolutionary theory, while implicitly using a definition of darwinism that means {to you} “reductive materialism”, is just asking for confusion.

    bFast: “Coyne argues it should refer to modern evolutionary theory.” And how does that differ to my definition with the exception of scope?

    The exception of scope IS a difference in definition.

    Per your definition, this paper is incoherent; King & Jukes, Non-Darwinian Evolution, Science 1969: “Most evolutionary change in proteins may be due to neutral mutations and genetic drift. Darwinism is so well established that it is difficult to think of evolution except in terms of selection …”

  63. 63
    bornagain says:

    Funny, a person on the street has no problem whatsoever knowing what someone means when they say Darwinian evolution. Namely, that all life arose via undirected material processes via common descent. But ironically highly educated Darwinists find it necessary to separate Darwinian evolution into different camps so as to protect it from falsification by junk DNA.
    Interestingly, the squabble now degenerates into how much junk DNA and natural selection makes you a true Darwinist and how much does not.

    I’m sure hard numbers for distinguishing true Darwinists from untrue Darwinists will be forthcoming in another 100 years or so. 🙂

  64. 64
    Virgil Cain says:

    Darwin refutes Zachriel:

    Variations neither useful nor injurious would not be affected by natural selection, and would be left either a fluctuating element, as perhaps we see in certain polymorphic species, or would ultimately become fixed, owing to the nature of the organism and the nature of the conditions.- On the Origins of Species sixth edition chapter 4, end of paragraph 1

  65. 65
    nkendall says:

    Dr. Moran,

    If you could. Please offer the 3 best pieces of evidence that you feel demonstrate, beyond any doubt, that evolution occurs strictly through random mutation and natural selection. Simply list the reason and briefly describe why you feel it supports neo-darwinism. Please provide brief discussion points here rather than referring to some other forum. If you need to reference some recent research paper, that’s fine. But explain why it supports your point.

    Thanks, regards.

  66. 66
    Andre says:

    Goodusername

    It is well known that Darwin borrowed that from Lamarck.

  67. 67
    Zachriel says:

    Andre: It is well known that Darwin borrowed that from Lamarck.

    It is well known that Darwin marshaled evidence from many different scientists in many different fields of study.

  68. 68
    Andre says:

    Zachriel

    And that is why the charge that he plagiarised others still haunts his legacy.

  69. 69
    Zachriel says:

    Andre: And that is why the charge that he plagiarised others still haunts his legacy.

    The work of other scientists are regularly cited in his published papers.

  70. 70
    EugeneS says:

    MN #61,

    I don’t think you are right in saying that code is reducible to mere ordering or sorting. Code (=rules, function) is inherently richer than the law-like necessity producing ordering/sorting. The laws of nature can produce only redundant regularity, randomness and transitions between the two. Functional sequences are always an artifact.

    See “Relationship between Random Sequence Complexity, Ordered Sequence Complexity and Functional Sequence Complexity”, chapter in “The First Gene”, D. Abel et. al. 2011.

  71. 71
    Andre says:

    Zachriel

    And allot of others he did not cite….

  72. 72
    Zachriel says:

    Andre: And allot of others he did not cite….

    Did you want to be specific?

  73. 73
    Larry Moran says:

    nkendall asks,

    If you could. Please offer the 3 best pieces of evidence that you feel demonstrate, beyond any doubt, that evolution occurs strictly through random mutation and natural selection.

    Why in the world would I do that?

    I don’t believe that “evolution occurs strictly through random mutation and natural selection.”

    Do you not understand anything I’ve been saying?

  74. 74
    bFast says:

    Larry Moran, “I don’t believe that “evolution occurs strictly through random mutation and natural selection.””
    Of course you do. You believe that natural selection plays no role in most random mutations, so you believe approximately, “most evolution occurs strictly through random mutation.” Isn’t that your theory?

    Your view differs from that of mainstream neo-Darwinism in that you place significantly more weight on random mutation, and significantly (even hugely) less weight on natural selection. However, from everything I have read from you, there remain only these two mechanisms.

  75. 75
    nkendall says:

    Fair enough Mr. Moran…It seems you have embraced the neutral theory and perhaps this “Constructive neutral theory of evolution” (CNE)? I have looked at that a bit. But even the neutral theory requires selection at some point, right? I don’t think you could do a standing vertical jump up the steep side of Mr. Improbable. The proposal (it really isn’t a theory) strikes me as something someone dreamed up during a DMT trip.

    I was not able to find any substance to it in my admittedly quick look. Do you have anything more specific to look at? Any evidence? It appears to be a collection of stories and a whole less plausible than the “just so” stories.

    I did see Michael Behe’s critique of it.

    http://behe.uncommondescent.co.....omplexity/.

    Have you commented on that?

    In addition to the problems he cites, it strikes me as extraordinarily unlikely, given the ubiquity of convergent and parallel evolution, that you could have the same collection of innumerable series of serendipitous neutral changes occurring which just happen to be pulled together–somehow–into a very useful complex function and in fact along with several novel functions at the same time and do so over and over again. Simon Conway Morris seems to rely on the power of small changes and especially natural selection to explain how the same sets of complex features could evolve time and time again. For example the transition of the reptile to mammals which he says occurred a few times and perhaps several times.

    Larry, I am afraid that by embracing this neutral drift theory, you have cast aside your good sense and that you, yourself will be adrift in the marketplace of ideas, isolated on an island of thought, just like one of your a nascent genes…forlorned on a small island in the vast fitness landscape.

  76. 76
    bFast says:

    nkendall, “the transition of the reptile to mammals which he [Simon Conway Morris] says occurred a few times and perhaps several times.” What is your source on this. I couldn’t find it by googling “morris reptile mammal”. I’d like to see what he has to say exactly.

  77. 77
    Mung says:

    bfast:

    Your view differs from that of mainstream neo-Darwinism in that you place significantly more weight on random mutation, and significantly (even hugely) less weight on natural selection.

    I don’t know if we can say that. Larry seems to be no great fan of Mutation-Driven Evolution. What else is there? Intelligent Design?

  78. 78
    nkendall says:

    bFast,

    Sorry for the delay I had a bit of trouble with the math problem Barry challenged me with in order to start typing here. Anyway…

    You may not find such a statement from Morris. This was something he shared with me in an email exchange shortly after I bought his book “Life’s Solutions”. I asked him about it because I read somewhere that this transition had occurred at least twice. I think it was a response to Ken Miller’s book “Finding Darwin’s God” which mentions that transition as a knock down proof of neo-darwinism. (I found it quite lacking…still a lot of gaps and lots of new features meaning new cell types and new proteins; a few sketches doesn’t cut it for me.) Morris was very responsive and after thanking me for buying his book, offered his regrets for not including any discussion on this transition. He said he had to consult with a colleague to say for sure how many times the transition occurred. I could probably dig around and find the email but it would be a lot of effort. In conveying what he said above, I used the word “perhaps” I think Morris actually used the word “probably” [the transition occurred several times]. I was being cautious.

    In any case I don’t know how you can square convergence with a neutral theory. Wouldn’t it be the case that these mutations that some day will become a valuable part of a new complex feature would have to occur multiple times given that they would be more likely to be lost (more likely compared to mutation / selection)? Actually I don’t know how you can square convergence with good old fashion mutation / selection but that is what Morris and others seem to be suggesting.

    Convergence for me is one of the most powerful pieces of evidence for intelligent design especially when you hear of things like the eye of the octopus and the ocelloid of the warnowiids.

  79. 79
    Larry Moran says:

    bFast says,

    Your view differs from that of mainstream neo-Darwinism in that you place significantly more weight on random mutation, and significantly (even hugely) less weight on natural selection. However, from everything I have read from you, there remain only these two mechanisms.

    You’ve been reading my comments and blog posts for years and you still think that?

    No wonder I call some of you IDiots. You deserve it.

  80. 80
    Mung says:

    Larry, other than mutation-driven evolution, what is left?

    The right amount of mutations at just the right time?

  81. 81
    bFast says:

    Spit it out, Larry Moran, what other mechanism is there? (Please understand, of course, that when I refer to mutation, I don’t simply mean “point mutation”, I mean any change to DNA that was the result of happenstance.)

  82. 82
    Box says:

    Moran:

    bfast: (…) there remain only these two mechanisms [mutation and natural selection].

    You’ve been reading my comments and blog posts for years and you still think that? No wonder I call some of you IDiots. You deserve it.

    I’m an even worse IDiot. In my understanding of any Darwinian theory the one and only source for novelty is (happenstance) mutation. After effects like natural selection and drift are anti-creative; they remove information.

  83. 83
    EugeneS says:

    Larry Moran,

    “Why in the world would I do that?”

    Indeed, why in the world?

    That one was my personal marker, professor Moran, from which I decided I would make my opinion. Of course, it’s not important to you, but just so you know your credibility has plummeted to zero.

  84. 84
    Zachriel says:

    EugeneS: Indeed, why in the world?

    He was asked a question loaded with a premise with which he disagreed.

    nkendall: Convergence for me is one of the most powerful pieces of evidence for intelligent design especially when you hear of things like the eye of the octopus and the ocelloid of the warnowiids.

    Biologists, from Darwin on, have considered it evidence of natural selection, and there is independent evidence to support the contention.

  85. 85
    EugeneS says:

    Zachriel @84,

    Why then did he not use the opportunity to type a couple of sentences explaining the gist of his argument? A true scientist, in my opinion, has a different attitude to educating the audience. If this is the passion of their life and profession, they should welcome every opportunity to promote knowledge.

    Credibility zero.

    In contrast, how many people just here at this blog patiently repeated themselves over and over again laying out their arguments!

  86. 86
    nkendall says:

    Zachriel at 84

    “Biologists, from Darwin on, have considered it evidence of natural selection, and there is independent evidence to support the contention.”

    What is the independent evidence?

    Convergent and parallel evolution are evidence for intelligent design. The same complex things happening over and over again is a pattern, a pattern of complexity. Recurring patterns of complexity sounds like the result of intelligent planning; it evokes foresight in my mind. Only through tortured logic could a neo-darwinist claim they are evidence of selection.

    Convergent and parallel evolution are an embarrassment to neo-darwinism. That’s why Gould went to such trouble to deny it. And that’s why darwinists seldom mention that the eye evolved so many times and why I had to dig so hard to find out that the reptile to mammal transition occurred multiple times. Convergent evolution is a label for their ignorance. But I do agree that of the two mechanisms offered by neo-darwinism–mutation and selection–selection has the best hope of explaining convergent evolution. But its a faint hope at that.

  87. 87
    Zachriel says:

    nkendall: What is the independent evidence?

    While no single thread can be separated completely from the tapestry of evolutionary history, consider the case of the convergence of prestin, a mammalian motor-protein involved in high-frequency hearing. When we plot its phylogeny, the phylogeny seems to place bats and whales together, contrary to their overall morphological phylogeny; but when we plot the phylogeny of non-synonymous substitutions, the standard phylogeny is revealed.

    nkendall: Convergent and parallel evolution are evidence for intelligent design.

    Intelligent design does not explain why the phylogeny of non-synonymous substitutions matches the morphological phylogeny, but it follows naturally from branching descent, and evolution by natural selection.

    nkendall: Convergent and parallel evolution are an embarrassment to neo-darwinism. That’s why Gould went to such trouble to deny it.

    Gould accepted convergence, but argued that convergence does not imply that evolution always follows predictable paths.

  88. 88
    nkendall says:

    Zachriel at 87

    Your comment is general. How many clades are you talking about? How many sample species within each clade? How many genes within those clades? And how many amino acid differences within each “gene?” I guess I would have to see the data. But my understanding is that there are stark differences between the phylogenies derived from morphology vs those derived from genetics, right?

    In any case, the point you are making, if true, only applies to Intelligent Design adherents who deny common descent. But Intelligent Design is agnostic, generally, on common descent, as am I. If you had asked by 5 years ago, I would have said common descent was a slam dunk. But now after the torrent of research coming out of ENCODE, I am not so sure and I am not even sure it matters…orphan genes, de novo genes, microRNAs, repeats all of which differ markedly between species (or families). I suspect that these things are more difficult to explain for evolutionists than your point about phylogeny matching between the genotype and the phenotype (in specific cases) is for those who don’t accept common descent.

    Regarding your comment about Gould and convergent evolution…of course many more examples of convergence are known now than 15-20 years ago when the Gould-Morris debate over convergence was raging. I think Gould might be a bit more circumspect about contingency were he alive today. What do you think? Isn’t it clear that many very complex things seem to occur over and over again…doesn’t that strike you as the result of a plan with a goal?

  89. 89
    Zachriel says:

    nkendall: Your comment is general.

    Prestin is specific, not general.

    nkendall: How many clades are you talking about? How many sample species within each clade? How many genes within those clades? And how many amino acid differences within each “gene?” I guess I would have to see the data.

    See Li et al., The hearing gene Prestin unites echolocating bats and whales, Current Biology 2010.
    http://www.cell.com/cms/attach.....5/mmc1.pdf
    (Figure S1)

    nkendall: But my understanding is that there are stark differences between the phylogenies derived from morphology vs those derived from genetics, right?

    Overall morphology, as well as overall genetics, places bats and whales on distant branches of the mammalian tree, but prestin stands out against this pattern, with the bat and whale prestin proteins closely resembling one another.

    nkendall: In any case, the point you are making, if true, only applies to Intelligent Design adherents who deny common descent.

    Intelligent Design doesn’t explain the pattern of synonymous substitutions, that is, unless Intelligent Design is empirically indistinguishable from old-fashioned evolution.

    nkendall: I think Gould might be a bit more circumspect about contingency were he alive today.

    Contingency is directly observed. See Blount et al., Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli, PNAS 2008. The scientific question concerns the relative importance of necessity and contingency in the history of evolution.

Leave a Reply