Researchers: “More than one-fourth of human proteins are one substitution away from containing a significant MAW, with the majority of replacements being predicted harmful.” Just above that, they say “This suggests that their absence is due to negative selection.” That’s a lot of negative selection going on. It feels somewhat like saying “The plagiarism checker provided considerable negative selection for the inappropriate use of others’ work.” Sure it did but that’s what it was designed to do.
Tag: proteins
Of 70,000 hitherto unknown viruses in the human gut, over 40% of proteins had no clear function
The reader comments that viruses cannot afford to carry around much non-functioning nucleic acid. More likely, the 43% that are mystery proteins do have a function. If even viruses are much more complex than we expect, what chance that all these complex systems arose by natural selection acting on random mutations (Darwinism)?
Film clip on the probability of a protein forming by chance passes 500k views
xcerpt: Putting the probabilities together means adding the exponents. The probability of getting a properly folded chain of one-handed amino acids, joined by peptide bonds, is one chance in 10^74+45+45, or one in 10^164 (Meyer, p. 212). This means that, on average, you would need to construct 10^164 chains of amino acids 150 units long to expect to find one that is useful.
Flap over use of term “intelligent design” in PNAS paper
It’s possible that what Phillips means by “positive Darwinian selection” is random selection that looks a lot like design. The sin is in actually using words that imply that that IS what it looks like. Just when it looks like they’ve hammered everything into submission, another bulge appears.
Protein found inside a meteorite
But then what are the chances that some of this stuff came from Earth in the first place? If there is indeed a road, the traffic might be going both ways.
Large and giant virus proteins not linked to any known virus lineage
So giant viruses often boost host metabolism instead of destroying it and “the team was still unable to link 20,000 major capsid proteins of large and giant viruses to any known virus lineage”? Creation ex nihilo? Hey, don’t laugh.. Look, these days, they can’t even get mouse or human sperm to buy into Darwinism. Why would giant viruses care?
Will setting proteins to music help us understand them?
Re proteins: “They have their own language, and we don’t know how it works,” he says. “We don’t know what makes a silk protein a silk protein or what patterns reflect the functions found in an enzyme. We don’t know the code.”
Nobody went downhill faster than DNA
Remember when everything you ever were or would be was
in your DNA? Now it’s proteins.
Researchers propose computer model of protein that may have existed when life began
At Rutgers: How did life arise on Earth? Rutgers researchers have found among the first and perhaps only hard evidence that simple protein catalysts – essential for cells, the building blocks of life, to function – may have existed when life began. Their study of a primordial peptide, or short protein, is published in the Read More…
Decidedly unDarwinian admissions re proteins
Philip Cunningham writes to note for us such moments in the literature: Abstract: (open access) Why life persists at the edge of chaos is a question at the very heart of evolution. Here we show that molecules taking part in biochemical processes from small molecules to proteins are critical quantum mechanically. Electronic Hamiltonians of biomolecules Read More…