Is Craig Venter’s Synthetic Cell Really Life?
Bioethicist Gregory Kaebnick, Ph.D., has an interesting take on the recently announced synthetic cell created by a team of researchers led by J. Craig Venter at the J. Craig Venter Instititute (JVCI). In a recent article in The Scientist entitled Is the “Synthetic Cell” about Life?, Kaebnick writes:
…the technical accomplishment is not quite what the JCVI press release claimed. It’s hard to see this as a synthetic species, or a synthetic organism, or a synthetic cell; it’s a synthetic genome of Mycoplasma mycoides, which is familiar enough. David Baltimore was closer to the truth when he told the New York Times that the researchers had not created life so much as mimicked it. It might be still more accurate to say that the researchers mimicked one part and borrowed the rest.
The explanation from the Venter camp is that the genome took over the cell, and since the genome is synthetic, therefore the cell is synthetic. But this assumes a strictly top-down control structure that some biologists now question. Why not say instead that the genome and the cell managed to work out their differences and collaborate, or even that the cell adopted the genome (and its identity)? Do we know enough to say which metaphor is most accurate?
