Uncommon Descent Serving The Intelligent Design Community

Exon Shuffling, and the Origins of Protein Folds

A frequently made claim in the scientific literature is that protein domains can be readily recombined to form novel folds. In Darwin’s Doubt, Stephen Meyer addresses this subject in detail (see Chapter 11). Over the course of this article, I want to briefly expand on what was said there. Defining Our Terms Before going on, it may be useful for me to define certain key terms and concepts. I will be referring frequently to “exons” and “introns.” Exons are sections of genes that code for proteins; whereas introns are sections of genes that don’t code for proteins. Proteins have multiple structural levels. Primary structure refers to the linear sequence of amino acids comprising the protein chain. When segments within this chain Read More ›

Is Larry Moran a conspiracy theorist?

That’s the only conclusion I can draw, after reading Professor Larry Moran’s latest reply to my post, No evidence for God’s existence, you say? A response to Larry Moran. More on that anon. I will, however, note for the record that Professor Moran has backed down from his original assertion that there is no evidence whatsoever for God’s existence. He now writes: When I say there’s no evidence for the existence of god(s) I mean that there is no “evidence” that stands up to close scrutiny… That brings up the question of what defines “valid evidence.” The short answer is “I don’t know” but I know it when I see it. “I know it when I see it.” Hmm. Where Read More ›