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Different psychiatric disorders linked to the same genes?


File:DNA simple.svg From Mark Fischetti at Scientific American:

Bipolar disorder, for example, was more similar to schizophrenia than to major depression even though clinicians may link bipolar disorder and depression, based on their symptoms. These insights could possibly reveal new treatments, says neurogeneticist Daniel Geschwind of the University of California, Los Angeles, one of the investigators. More.

It’s becoming increasingly evident (see the stories below) that a great deal of what we need to know about a person (or any life form) is not in their genes.

See also: At PLOS: “Genes – way weirder than you thought”

Bale monkeys more closely related to sister species than same species in different locationsThe “biological species concept” is yet another textbook dead zone.

Girl got mostly a double set of her dad’s genes, is almost a twin. She has some problems but she is 11 years old. Yes, that was the sound of another lectern splintering in the near distance.

Almost one in five genes’ coding status is unresolved Researchers: We believe that the three reference databases currently overestimate the number of human coding genes by at least 2000, complicating and adding noise to large-scale biomedical experiments.


Do all genes affect every complex trait? Veronique Greenwood: The roots of many traits, from how tall you are to your susceptibility to schizophrenia, are far more tangled. In fact, they may be so complex that almost the entire genome may be involved in some way


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