DNA damage

From ScienceDaily: When a building is damaged, a general contractor often oversees various subcontractors — framers, electricians, plumbers and drywall hangers — to ensure repairs are done in the correct order and on time. Similarly, when DNA is damaged, a molecular general contractor oversees a network of genetic subcontractors to ensure that the diverse cellular tasks needed to protect and repair the genome are carried out correctly and on time. Scientists have known for some time that a master gene named SOG1 acts like a general contractor for repair, coordinating with various genetic subcontractors of the plant cell to mount an effective DNA damage response. But, it wasn’t clear which specific genes were among the subcontractors, nor how SOG1 interacted Read More ›