Intelligent Design

Controlling the waves of dynamic, far from equilibrium states: the NF-kB system of transcription regulation.

I have recently commented on another thread: about a paper that (very correctly) describes cells as dynamic, far from equilibrium systems, rather than as “traditional” machines. That is true. But, of course, the cell implements the same functions as complex machines do, and much more. My simple point is that, to do that, you need […]

Intelligent Design

Mechanosensing and Mechanotransduction: how cells touch their world.

Fig. 1: Cnidaria are probably one of the most ancient phyla of known Metazoa.   Metazoa, or multicellular organisms, are one of the amazing “novelties” in natural history. At some point, single eukaryotic cells begin to be organized in a new, incredibly complex plan: a multicellular organism. It is well known and understood that one […]

Intelligent Design

Isolated complex functional islands in the ocean of sequences: a model from English language, again.

      A few days ago, Denyse published the following, very interesting, OP: Laszlo Bencze offers an analogy to current claims about evolution: Correcting an F grade paper Considering that an example is often better than many long discussions, I have decided to use part of the analogy presented there by philopsopher and photographer Laszlo […]

Intelligent Design

Defending Intelligent Design theory: Why targets are real targets, probabilities real probabilities, and the Texas Sharp Shooter fallacy does not apply at all.

      The aim of this OP is to discuss in some order and with some completeness a few related objections to ID theory which are in a way connected to the argument that goes under the name of Texas Sharp Shooter Fallacy, sometimes used as a criticism of ID. The argument that the […]

Intelligent Design

What are the limits of Random Variation? A simple evaluation of the probabilistic resources of our biological world

Coming from a long and detailed discussion about the limits of Natural Selection, here: What are the limits of Natural Selection? An interesting open discussion with Gordon Davisson I realized that some attention could be given to the other great protagonist of the neo-darwinian algorithm: Random Variation (RV). For the sake of clarity, as usual, […]

Intelligent Design

What are the limits of Natural Selection? An interesting open discussion with Gordon Davisson

An interesting discussion, still absolutely open, has taken place in the last few days between Gordon Davisson and me on the thread: What? Only an “extremely occasional” mutation is beneficial? But Darwinism… ? Some very good friends, like Dionisio, Mung and Origenes, seem to have appreciated the discussion, which indeed has touched important issues. Origenes […]

Intelligent Design

Interesting proteins: DNA-binding proteins SATB1 and SATB2

With this OP, I am starting a series (I hope) of articles whose purpose is to present interesting proteins which can be of specific relevance to ID theory, for their functional context and evolutionary history. DNA-binding protein SATB1 SATB1 (accession number Q01826) is a very intriguing molecule. Let’s start with some information we can find at […]

Intelligent Design

The amazing level of engineering in the transition to the vertebrate proteome: a global analysis

As a follow-up to my previous post: The highly engineered transition to vertebrates: an example of functional information analysis I am presenting here some results obtained by a general application, expanded to the whole human proteome, of the procedure already introduced in that post. Main assumptions. The aim of the procedure is to measure a well defined […]

Information Intelligent Design

The highly engineered transition to vertebrates: an example of functional information analysis

In the recent thread “That’s gotta hurt” Bill Cole states: I think over the next few years 3 other origins (my note: together with OOL), will start to be recognized as equally hard to explain: The origin of eukaryotic cell: difficult to explain the origin of the spliceosome, the nuclear pore complex and chromosome structure. […]

Genetics Genomics Intelligent Design

Information jumps again: some more facts, and thoughts, about Prickle 1 and taxonomically restricted genes.

  My previous post about information jumps, based on the example of the Prickle 1 protein, has generated a very interesting discussion, still ongoing. I add here some more thoughts about an aspect which has not been really analyzed in the first post, and which can probably contribute to the discussion. I will give here […]