VIDEO: Doug Axe on making odds on getting to a protein by chance in Amino Acid sequence space
In Illustra Media’s Darwin’s Dilemma, there is a clip on proteins as islands of function in amino acid sequence space: https://www.youtube.com/watch?v=h38Xi-Jz9yk Food for thought. As a stimulus to such, let us next note how the bloggist Wintery Knight has given an interesting summary of the challenges involved if a chance-dominated process is invoked for a hypothetical 100-AA polypeptide: But, some will object, it’s not just chance involved! That is, they are appealing to self-organisation and/or mechanical necessity, or incremental complexification — a sort of pre-life evolution. Especially, with RNA acting as a catalyst and potential information store. Mechanical necessity, a forced sequence of bonds, is both counter to what we know of the chemistry of both AA and D/RNA chaining, Read More ›