Intelligent Design

Elaborated Tunnel Architectures in Enzyme Systems point to a designed setup

Elaborated Tunnel Architectures in Enzyme Systems point to a designed setup https://reasonandscience.catsboard.com/t2062-proteins-how-they-provide-striking-evidence-of-design#9672 RNA and DNA belong to the four basic building blocks of life. They are complex macromolecules made of three constituents: the base, the backbone, which is the ribose five-carbon sugar, and phosphate, the moiety which permits DNA polymerization and catenation of monomers, to Read More…

Intelligent Design

An updated ( but not exhaustive) list of how to detect intelligent design

How to recognize the signature of (past) intelligent action https://reasonandscience.catsboard.com/t2805-how-to-recognize-the-signature-of-past-intelligent-action Claim: Herbert Spencer:  “Those who cavalierly reject the Theory of Evolution, as not adequately supported by facts, seem quite to forget that their own theory is supported by no facts at all.” Reply: Contrasting and comparing “intended” versus “accidental” arrangements leads us to the notion of design. Read More…

Intelligent Design

Review: J. W. Thornton (2022): Simple mechanisms for the evolution of protein complexity

Review: J. W. Thornton (2022): Simple mechanisms for the evolution of protein complexity https://reasonandscience.catsboard.com/t2706-main-topics-on-proteins-and-protein-synthesis#9622 Proteins are tiny models of biological complexity: specific interactions among their many amino acids cause proteins to fold into elaborate structures, assemble with other proteins into higher-order complexes, and change their functions and structures upon binding other molecules.  Comment: Merriam-Webster describes the word “elaborate” as: “planned Read More…

Intelligent Design

Extreme genome repair, and remarkable morphogenesis by self-assembly point to design

Extreme genome repair, and remarkable morphogenesis by self-assembly point to design https://reasonandscience.catsboard.com/t2061p275-my-articles#9626 Extreme Genome Repair (2009): If its naming had followed, rather than preceded, molecular analyses of its DNA, the extremophile bacterium Deinococcus radiodurans might have been called Lazarus. After shattering of its 3.2 Mb genome into 20–30 kb pieces by desiccation or a high dose of Read More…

Intelligent Design

How would a Last Universal Common Ancestor not have gone extinct because of mutations?

Let’s suppose there was a first Last Universal Common Ancestor (LUCA) or a small population of it. How did it overcome deleterious harmful mutations, in order not to go extinct?   M.LYNCH (2003): Although uncertainties remain with respect to the form of the mutational-effect distribution, a great deal of evidence from several sources strongly suggests that the Read More…