Defending our Civilization

Inimitable: Food for thought. U/D: When it reaches the pharmacy . . . U/D May 19, another Lozano interview: And, oh yes, breaking 1: Mr Trump is praising — yes, I am NOT using, “touting” — a promising vaccination. Announcement by the firm, here. Breaking, no 2, courtesy Daily Mail as usual: Of course, the now standard, it’s risky is in the subheads. U/D: Video: Compare our Texas Doctor’s remarks. And then, there is the latest from Dr Raoult: Whose report do you believe, why? END

As Cardinal Pell has been recently cleared, perhaps some may be willing to learn from this telling vid: No, Virginia, you do not get a world from no-thing. END

Let’s look at daily confirmed cases: and at a seven-day rolling average for deaths: South Korea seems to have beaten this wave. Several advanced countries show a stubborn plateau, which is reflected in the linear ongoing growth. It is not confined to the US, we need to learn from the Koreans; who BTW are HCQ users. The “mesa” for China underscores the observation that Chinese data has to be regarded with care. END

There is a report that Azithromycin is far more than an antibiotic. Some may wish to watch an interview with Dr. Michael Lisanti on antibiotics for COVID-19 and cancer. But — without endorsing as “proved” fact — let’s cut to the chase scene: COVID-19 coronavirus is particularly dangerous for the elderly or those with aging-related senescent illnesses like diabetes, cancer, heart disease, and lung disease. As Professor Lisanti said in a statement on his new paper in the journal Aging, “If you look at the host receptors of COVID-19, they are related to senescence. Two proteins have been proposed to be the cellular receptors of COVID-19: one is CD26 – a marker of senescence, and the other, ACE-2, is also Read More ›

Ventilators are a key treatment for Covid-19, and there has been a wave of interest concerning development of low-cost ventilators; especially with a projected Covid-19 wave in excess of 100 millions for Africa. Here, then, is the Israel developed AmboVent, one of something like 300 fast-track initiatives to develop such globally: Video: This is of course one of several designs pivoting on the nearly ubiquitous manual respirator bulb, as per a suggestion that has been on the table for some time. Now we see a [near-?] commercial product. Video on the suggestion: Their blurb: The AmboVent initiative is led, by the Israeli Air Force (IAF) 108 electronic depot in partnership with Magen David Adom (MDA) (Israel’s red cross). The R&D Read More ›

Jerry has again hit gold, and so here is Dr Didier Raoult, in his own voice, with English sub-titles: Let us view and discuss. U/D: it will be helpful to take time to follow this video also, where others have a say. (As time permits, I will put up some screen captures as updates below.) Let us view and let us think together. END F/N: Let me stack screen shots, first, who and what we are dealing with: Next, the study: Note, for reference, its approval: Research protocol approved by the ANSM [= “Agence Nationale de Sécurité du Médicament et des Produits de Santé (ANSM)”, i.e. National Agency for the Safety of Medicines and Health Products] and the Île-de-France CPP Read More ›

Jerry drew our attention last night to a radio interview by Dr Vladimir Zelenko. In this interview, he summarises his approach and rationale, giving results and making several announcements. (Unfortunately, the media cannot be embedded at UD as it is not YT. Kindly, go here; and make sure your browser has no active ad blocker.) On listening last night, here are my first observations on highlight points: Brazil and Israel are doing his early treatment, clinical diagnosis (backed up by nasal swab test), outpatient-oriented dosage for vulnerable patients protocol, ALT-1. He has treated 405 in that profile and sees 95% reduction on the expected death rate for the n-BAU baseline. He points out that the Raoult [by implication] protocol, which Read More ›

It is clear that we need to re-think how we go about doing science to warrant approaches to the pandemic. So, allow me to headline a comment from the double-blind thread: KF, 16: >> I am also thinking back to the old “Scientific Method” summary we were taught in schools and its roots in Newton’s Opticks, Query 31: As in Mathematicks, so in Natural Philosophy, the Investigation of difficult Things by the Method of Analysis, ought ever to precede the Method of Composition. This Analysis consists in making Experiments and Observations, and in drawing general Conclusions from them by Induction, and admitting of no Objections against the Conclusions, but such as are taken from Experiments, or other certain Truths. For Read More ›

Shortly after I posted yesterday on whether placebo based studies are properly a gold standard, one of our common objectors, JT, linked the Guardian. Perhaps, he did not realise just how aptly it illustrates my point. I therefore responded, as I now headline as a shop window case- in- point illustration of what is going wrong with medical testing, linked statistics and linked ethics . . . not to mention, too much of the media and the way we tend to think: This is part of why I have written as I have in the OP: [Guardian, annotated:] >>The French doctor Didier Raoult has claimed [–> has reported, on now almost 3,000 patients, under a test protocol approved by relevant Read More ›

As we have seen in recent weeks as Covid-19 and Hydrochloroquine cocktail treatments have been on the table, there is a clear tendency to view and treat double-blind placebo controlled testing as a “gold standard” yardstick and to then use such to discount and dismiss whatever does not “measure up” such as Professor Raoult’s work over in France. I will now argue in outline that such an attitude is selectively hyperskeptical, seriously ethically, epistemologically and logically flawed, and sets up a crooked yardstick. It is a commonplace in Medical research that arguably more lives were saved, net, than perished through the tainted medical studies in the Nazi death camps. However, the taint was seen as so serious that a programme Read More ›

Prof Raoult’s web site hosts an interesting map, under the title, “Pays où l’hydroxychloroquine est recommandée”: India, of course, has the further approval for prophylaxis. That’s significant, as talk on vaccines tends to point to 12 – 18 months and double-blind, placebo controlled tests in progress or about to start in the US look likely to take more than a year. Meanwhile, OWID tracks how time to double to current number of deaths — probably the best statistic — is continuing to stretch out: (Notice, the S-curves and driving impulses.) Likewise, we can see the daily cases clearly peaking (for THIS wave . . . notice, Wave 2 for China and even an uptick to a Wave 3): This is Read More ›

HT, BA77, here is a plot of CFR vs median age, with size of bubble keyed to number of fatalities: In this context, Prof Didier Raoult’s 1061 case study’s low fatality rate for elderly persons, 0.5% as reported, seems quite significant. Related, here is the Chinese CDC report on CFR by age: Then, we may note Raoult’s observed pattern for treatment: I trust these will be helpful. END

Recently, we here at UD saw that global trend lines are curving over from exponential growth in new Covid-19 cases. Likewise, health authorities have been talking of the US and the UK peaking in perhaps ten days. Where I am, we are still growing: one, two, five, nine total. (And no, Black the Ripper is not credibly a Covid-19 case.) Here’s a graphic that gives pause, with labelled phases — recall, the crest of new infections is the inflexion point on the growing arm of the S-curve of cumulative cases: But, the further consideration is, onward waves triggered by fresh outbreaks or new strains once lock-downs . . . which cannot be long sustained . . . are relaxed: These Read More ›

. . . and, they expect a secondary wave. Sermo is a global Doctors’ forum site, which allows building of a global consensus of Physicians. As a part of its efforts, it has had a “statistically significant” survey of over 6,000 doctors, regarding Covid-19. Excerpting the just linked report: Largest Statistically Significant Study by 6,200 Multi-Country Physicians on COVID-19 Uncovers Treatment Patterns and Puts Pandemic in Context April 2, 2020 Sermo Reports on Hydroxychloroquine Efficacy, Rise in Prophylaxis Use; Over 80% Expect 2nd Outbreak New York, New York – April 2, 2020 – Widespread confusion, conflicting reports, inconsistent testing, and off-indication use of existing and experimental drugs has resulted in no single source of information from the frontlines. To create a Read More ›

Here is a panel discussion for a rapidly organised conference: We need to hear this, where 44 million donated tablets are already in hand. END