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Genetics

Study: Enzymes act very specifically to control double-strand breaks

At ScienceDaily: "It's like an engine mechanic who has a set of tools at his disposal," Dr. Sung said. "The tool he uses depends on the issue that needs to be repaired. In like fashion, each DNA repair tool in our cells is designed to repair a distinctive type of break in our DNA." Read More ›

Is biology “hiding its deepest mysteries”?

Physics was “hiding its deepest mysteries” thousands of years ago too before anyone uncovered laws for how it works. There are still mysteries in physics, of course, but they are now more basic. The laws are now known. Let's hope the same proves true for biology. Read More ›

Researchers made films to help explain the spliceosome

A friend tells us that Michael Lynch of the Biodesign Institute of Arizona State) has argued that the spliceosome is so complex, because it just couldn’t help being that way. Here’s a question: How did such an explanation get to be called “science”? Read More ›

Squid self-edit their genomes

Open access: Abstract: In eukaryotic cells, with the exception of the specialized genomes of mitochondria and plastids, all genetic information is sequestered within the nucleus. This arrangement imposes constraints on how the information can be tailored for different cellular regions, particularly in cells with complex morphologies like neurons. Although messenger RNAs (mRNAs), and the proteins that they encode, can be differentially sorted between cellular regions, the information itself does not change. RNA editing by adenosine deamination can alter the genome’s blueprint by recoding mRNAs; however, this process too is thought to be restricted to the nucleus. In this work, we show that ADAR2 (adenosine deaminase that acts on RNA), an RNA editing enzyme, is expressed outside of the nucleus in Read More ›

At Justin Brierley’s Unbelievable: The scientific case for Adam and Eve

"He [Swamidass] is joined by atheist biologist Nathan Lents who has given his support to the book, believing that it may help Christians who hold to a traditional understanding of the Adam and Eve story, to also accept evolutionary science. " Read More ›

Expert contra Dawkins, why eugenics wouldn’t really work

David Curtis: We can now measure genetic potential directly from genetic markers and what we know from this is that these genetic predictors perform extremely badly. We can also tell that there are many important, very rare genetic variants which we will never be able to identify. Read More ›